Antiphospholipid syndrome primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Feham Tariq, MD [2]

Overview

Primary Prevention

In addition to anticoagulation, attention should be paid to minimizing the contribution of reversible risk factors for recurrent thrombosis. During the perioperative period, this may include minimizing the period when patients are off anticoagulation, initiating early ambulation, and other measures to reduce venous stasis Randomized controlled trials have addressed the secondary prevention of thromboses. These trials include APLASA[1],

References

  1. Erkan D, Harrison MJ, Levy R, Peterson M, Petri M, Sammaritano L; et al. (2007). "Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: a randomized, double-blind, placebo-controlled trial in asymptomatic antiphospholipid antibody-positive individuals". Arthritis Rheum. 56 (7): 2382–91. doi:10.1002/art.22663. PMID 17599766.

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