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==Overview==
==Overview==
[[Chest X-ray]] is a sensitive [[diagnostic]] test for inhalation [[anthrax]].  [[Chest X-ray]] abnormalities associated with inhalation [[anthrax]] include [[mediastinal widening]], paratracheal fullness, [[pleural effusion]]s, parenchymal infiltrates, and [[mediastinal]] [[lymphadenopathy]].


==Chest X Ray==
==Chest X Ray==
* The earliest detectable specific finding indicative of inhalational anthrax is [[mediastinal widening]] on posteroanterior chest X-rays. However, mediastinal widening is common in patients presenting at the emergency department.<ref>{{cite book | last = Turnbull | first = Peter | title = Anthrax in humans and animals | publisher = World Health Organization | location = Geneva, Switzerland | year = 2008 | isbn = 9789241547536 }}</ref>


===Inhalational Anthrax===
* [[Lymphatic]] stasis resulting from the damaged [[lymph nodes]] leads to dilatation of [[pulmonary]] [[lymphatics]] which originate in the [[pleura]] and drain towards the [[hilum]], following interlobular septa in association with [[blood vessels]]. The [[lymphatic]] stasis manifests as an early onset [[pleural effusion]] and peripheral infiltrates, representing thickened bronchovascular bundles, detectable on [[chest X-ray]]. These findings mark fully developed initial stage illness.<ref>{{cite book | last = Turnbull | first = Peter | title = Anthrax in humans and animals | publisher = World Health Organization | location = Geneva, Switzerland | year = 2008 | isbn = 9789241547536 }}</ref>
 
* The earliest detectable specific finding indicative of inhalational anthrax is [[mediastinal widening]] on posteroanterior chest X-rays. However, mediastinal widening is not a rare finding in a series of patients presenting at a emergency department.
 
* Lymphatic stasis resulting from the damaged lymph nodes leads to dilatation of pulmonary [[lymphatics]] which originate in the pleura and drain towards the hilum, following interlobular septa in association with blood vessels. The lymphatic stasis manifests as an early onset [[pleural effusion]] and peripheral infiltrates, representing thickened bronchovascular bundles, detectable on chest X-ray. These findings mark fully developed initial stage illness.
 
* Ultimately, the bacteria escape from the damaged [[lymph node]]s and invade the blood stream via the thoracic duct. Once the [[bacteremia]] and associated [[toxemia]] reach a critical level, the severe symptoms characteristic of the acute phase illness are manifest. During the acute phase illness, damage of the lung tissue becomes apparent on X-ray. This damage results from the action of [[anthrax toxin]] on the [[endothelium]] of the lung’s capillary bed. Primary damage of the lung is not normally a feature of the initial phase illness and primary pulmonary infection is an uncommon presentation.
 
* The X-ray picture of the lung appears to be a very sensitive diagnostic aid with multiple abnormalities, including [[mediastinal widening]], paratracheal fullness, [[pleural effusion]]s, parenchymal infiltrates, and mediastinal [[lymphadenopathy]].<ref>{{cite book | last = Turnbull | first = Peter | title = Anthrax in humans and animals | publisher = World Health Organization | location = Geneva, Switzerland | year = 2008 | isbn = 9789241547536 }}</ref>


==Image Gallery==
==Image Gallery==
<gallery>
<gallery>
Image:Anthrax CXR01.jpg|This right-lateral chest x-ray revealed evidence of a pulmonic infection 4 days after this patient had been exposed to the bacillus, Bacillus anthracis, the cause of the disease known as anthrax. <SMALL><SMALL>''[http://phil.cdc.gov/phil/  Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
Image:Anthrax CXR01.jpg|This right-lateral chest x-ray revealed evidence of a pulmonic infection 4 days after this patient had been exposed to the bacillus, Bacillus anthracis, the cause of the disease known as anthrax. <SMALL><SMALL>''[http://phil.cdc.gov/phil/  Adapted from Public Health Image Library (PHIL), Centers for Disease Control and Prevention.]''<ref name="PHIL">{{Cite web | title = Public Health Image Library (PHIL), Centers for Disease Control and Prevention | url = http://phil.cdc.gov/phil/}}</ref></SMALL></SMALL>
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[[Category:Zoonoses]]
[[Category:Zoonoses]]
[[Category:Medical disasters]]
[[Category:Medical disasters]]
[[Category:Emergency mdicine]]
[[Category:Up-To-Date]]
[[Category:Infectious disease]]
[[Category:Infectious disease]]
[[Category:Dermatology]]
[[Category:Pulmonology]]
[[Category:Gastroenterology]]

Latest revision as of 20:25, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Chest X-ray is a sensitive diagnostic test for inhalation anthrax. Chest X-ray abnormalities associated with inhalation anthrax include mediastinal widening, paratracheal fullness, pleural effusions, parenchymal infiltrates, and mediastinal lymphadenopathy.

Chest X Ray

  • The earliest detectable specific finding indicative of inhalational anthrax is mediastinal widening on posteroanterior chest X-rays. However, mediastinal widening is common in patients presenting at the emergency department.[1]

Image Gallery

References

  1. Turnbull, Peter (2008). Anthrax in humans and animals. Geneva, Switzerland: World Health Organization. ISBN 9789241547536.
  2. Turnbull, Peter (2008). Anthrax in humans and animals. Geneva, Switzerland: World Health Organization. ISBN 9789241547536.
  3. 3.0 3.1 3.2 3.3 3.4 "Public Health Image Library (PHIL), Centers for Disease Control and Prevention".