Acrodermatitis chronica atrophicans history and symptoms: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
No edit summary
 
(16 intermediate revisions by the same user not shown)
Line 3: Line 3:
{{ACA}}
{{ACA}}
==Overview==
==Overview==
 
History of [[tick bite]], [[Lyme disease|erythema migrans]] or other [[symptoms]] of [[lyme disease]], and [[rheumatology|rheumatological]] [[symptoms]] have been presented in [[patients]] with [[acrodermatitis chronica atrophicans]]. Since there could be several years between the [[tick]] [[bite]] and development of [[skin]] lesions, absence of [[tick]] [[bite]] in [[patients]]' history never exclude the [[diagnosis]]. [[Symptoms]] and different forms of [[skin]] involvement in [[acrodermatitis chronica atrophicans]] are dependent to duration of the [[disease]]. [[Symptoms]], such as sclerotic [[skin]] changes, [[pain]] and burning, [[edema]] and [[B symptoms|constitutional symptoms]] have been observed in [[acrodermatitis chronica atrophicans]]. Half of [[patients]] with [[acrodermatitis chronica atrophicans]] experience [[symptoms]] of [[peripheral neuropathy]], such as [[paresthesia]] and [[hypesthesia]]. [[Symptoms]] of [[peripheral neuropathy]] can occure at the exact site of [[acrodermatitis chronica atrophicans]]'s lesion or at other sites. Involvement of [[leg|lower limb]] is more common compared to the [[upper limb]]. In some cases episodic [[knee]] [[joint]] [[effusion]] has been observed.
==History and Symptoms==
==History and Symptoms==
===History===
===History===
The following are some of the common findings in [[patients]]' history:<ref name="pmid3577484">{{cite journal| author=Asbrink E, Hovmark A, Olsson I| title=Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients. | journal=Zentralbl Bakteriol Mikrobiol Hyg A | year= 1986 | volume= 263 | issue= 1-2 | pages= 253-61 | pmid=3577484 | doi=10.1016/s0176-6724(86)80128-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3577484  }} </ref><ref name="pmid6084922">{{cite journal| author=Asbrink E, Hovmark A, Hederstedt B| title=The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer. | journal=Acta Derm Venereol | year= 1984 | volume= 64 | issue= 6 | pages= 506-12 | pmid=6084922 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6084922  }} </ref>
The following are some of the common findings in [[patients]]' history:<ref name="pmid3577484">{{cite journal| author=Asbrink E, Hovmark A, Olsson I| title=Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients. | journal=Zentralbl Bakteriol Mikrobiol Hyg A | year= 1986 | volume= 263 | issue= 1-2 | pages= 253-61 | pmid=3577484 | doi=10.1016/s0176-6724(86)80128-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3577484  }} </ref><ref name="pmid6084922">{{cite journal| author=Asbrink E, Hovmark A, Hederstedt B| title=The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer. | journal=Acta Derm Venereol | year= 1984 | volume= 64 | issue= 6 | pages= 506-12 | pmid=6084922 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6084922  }} </ref><ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695  }} </ref><ref name="pmid33085436">{{cite journal| author=| title=StatPearls | journal= | year= 2021 | volume=  | issue=  | pages=  | pmid=33085436 | doi= | pmc= | url= }} </ref>
*[[Tick bite]]  
*[[Tick bite]]  
**Since there could be several years between the [[tick]] [[bite]] and development of [[skin]] lesions, absence of [[tick]] [[bite]] in [[patients]]' history is not meaningful alone.
**Since there could be several years between the [[tick]] [[bite]] and development of [[skin]] lesions, absence of [[tick]] [[bite]] in [[patients]]' history never exclude the [[diagnosis]].
**Based on a study done on 693 [[patients]] with [[acrodermatitis chronica atrophicans]] approximately 85% remembered a [[tick]] [[bite]].  
*[[Lyme disease|Erythema migrans]]
*[[Lyme disease|Erythema migrans]]
**Some of the [[patients]] in a study experienced [[Erythema Migrans|erythema migrans]] 6 months to 8 years before [[acrodermatitis chronica atrophicansis]] development.
**Some of the [[patients]] in a study experienced [[Erythema Migrans|erythema migrans]] 6 months to 8 years before [[acrodermatitis chronica atrophicansis]] development.
Line 17: Line 16:


===Symptoms===
===Symptoms===
*It usually involves [[Extension (kinesiology)|extensor surfaces]] of the [[Limb (anatomy)|acral regions of limbs]] beginning with an [[inflammatory]] stage (bluish red discoloration and [[edema]] followed by an atrophic phase. [[Sclerosis|Sclerotic]] [[skin]] plaques may also develop.  
*[[Symptoms]] and different forms of [[skin]] involvement in [[acrodermatitis chronica atrophicans]] are dependent to duration of the [[disease]].<ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695  }} </ref>
*It usually involves [[Extension (kinesiology)|extensor surfaces]] of the [[Limb (anatomy)|acral regions of limbs]] beginning with an [[inflammatory]] stage (bluish red discoloration and [[edema]] followed by an [[atrophy|atrophic phase]]).  
*[[Sclerosis|Sclerotic]] [[skin]] plaques may also develop.  
*[[Acrodermatitis chronica atrophicans]] can progress and cause [[wrinkle]].
*[[Acrodermatitis chronica atrophicans]] can progress and cause [[wrinkle]].
*The following are [[symptoms]] have been observed in [[acrodermatitis chronica atrophicans]]:<ref name="pmid3577484">{{cite journal| author=Asbrink E, Hovmark A, Olsson I| title=Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients. | journal=Zentralbl Bakteriol Mikrobiol Hyg A | year= 1986 | volume= 263 | issue= 1-2 | pages= 253-61 | pmid=3577484 | doi=10.1016/s0176-6724(86)80128-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3577484  }} </ref><ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695  }} </ref>
*The following are [[symptoms]] have been observed in [[acrodermatitis chronica atrophicans]]:<ref name="pmid3577484">{{cite journal| author=Asbrink E, Hovmark A, Olsson I| title=Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients. | journal=Zentralbl Bakteriol Mikrobiol Hyg A | year= 1986 | volume= 263 | issue= 1-2 | pages= 253-61 | pmid=3577484 | doi=10.1016/s0176-6724(86)80128-6 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3577484  }} </ref><ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695 }} </ref><ref name="KaminskyMaisonobe2020">{{cite journal|last1=Kaminsky|first1=Anne-Laure|last2=Maisonobe|first2=Thierry|last3=Lenglet|first3=Timothée|last4=Psimaras|first4=Dimitri|last5=Debs|first5=Rabab|last6=Viala|first6=Karine|title=Confirmed cases of Neuroborreliosis with involvement of peripheral nervous system|journal=Medicine|volume=99|issue=40|year=2020|pages=e21986|issn=0025-7974|doi=10.1097/MD.0000000000021986}}</ref><ref name="Muller2012">{{cite journal|last1=Muller|first1=Kurt E.|title=Damage of Collagen and Elastic Fibres by Borrelia Burgdorferi – Known and New Clinical and Histopathological Aspects|journal=The Open Neurology Journal|volume=6|issue=1|year=2012|pages=179–186|issn=1874205X|doi=10.2174/1874205X01206010179}}</ref><ref name="pmid32512846">{{cite journal| author=Scott JD| title=Presentation of Acrodermatitis Chronica Atrophicans Rashes on Lyme Disease Patients in Canada. | journal=Healthcare (Basel) | year= 2020 | volume= 8 | issue= 2 | pages=  | pmid=32512846 | doi=10.3390/healthcare8020157 | pmc=7349802 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32512846 }} </ref>
**Sclerotic [[skin]] lesions
**Sclerotic [[skin]] lesions
**[[Pain]]
**[[Pain]] and burning
**[[Edema]]
**[[Edema]]
**[[Wrinkles]]
**[[Wrinkles]]
**[[B symptoms|Constitutional symptoms]]
**[[Peripheral neuropathy]] (develop in half of [[patients]])
***Such as [[paresthesia]] and [[hypesthesia]]
***Some [[patients]] develop [[symptoms]] related to [[peripheral neuropathy]] at the exact site of [[acrodermatitis chronica atrophicans]]'s lesion, nevertheless there are other [[patients]] that experienced these [[symptoms]] at other sites.
***Most of the times it presents as asymmetric distal sensory disturbance, which could be [[pain|painful]] or [[pain|painless]].
**[[Arthropathy]]
**[[B symptoms|Constitutional symptoms]] (such as [[fever]] and [[fatigue]])
**[[Joint]] deformities
**[[Joint]] deformities
**Band-like [[induration]] on [[Limb (anatomy)|extremities]]
*Based on a study done on 693 [[patients]] suffering from [[acrodermatitis chronica atrophicans]]:<ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695  }} </ref>
*Based on a study done on 693 [[patients]] suffering from [[acrodermatitis chronica atrophicans]]:<ref name="pmid33550695">{{cite journal| author=Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F| title=Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients. | journal=J Intern Med | year= 2021 | volume=  | issue=  | pages=  | pmid=33550695 | doi=10.1111/joim.13266 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33550695  }} </ref>
**Involvement of [[leg|lower limb]] (70%) has been more common compared to [[upper limb]] (45.2%).
**Involvement of [[leg|lower limb]] (70%) has been more common compared to [[upper limb]] (45.2%).
**In 42.4% of cases acral involvement occurred bilaterally.  
**In 42.4% of cases acral involvement occurred bilaterally.  
**Only 2 among 693 [[patients]] had [[skin]] involvement on areas other than [[Limb (anatomy)|extremities]].
**Only 2 among 693 [[patients]] had [[skin]] involvement on areas other than [[Limb (anatomy)|extremities]].
**Less than 3% of studied [[patients]] had [[symptoms]] such as [[Nodule (medicine)|nodule]], [[arthritis]], [[muscle atrophy]], [[joint]] deformities and [[paresis]].
**Less than 3% of studied [[patients]] had [[symptoms]] such as [[Nodule (medicine)|nodule]], [[arthritis]], [[itch|itching]], [[muscle atrophy]], [[joint]] deformities and [[paresis]].  
**Small fraction of [[patients]] didn't experience any [[skin]] discoloration and their main presentations were [[edema]] and [[atrophy|atrophic changes]].
*In some cases episodic [[knee]] [[joint]] [[effusion]] has been observed.<ref name="pmid32512846">{{cite journal| author=Scott JD| title=Presentation of Acrodermatitis Chronica Atrophicans Rashes on Lyme Disease Patients in Canada. | journal=Healthcare (Basel) | year= 2020 | volume= 8 | issue= 2 | pages=  | pmid=32512846 | doi=10.3390/healthcare8020157 | pmc=7349802 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32512846  }} </ref>
*In some cases [[symptoms]] such as [[Personality|personality changes]] have been reported due to involvement of central nervous system.<ref name="pmid32512846">{{cite journal| author=Scott JD| title=Presentation of Acrodermatitis Chronica Atrophicans Rashes on Lyme Disease Patients in Canada. | journal=Healthcare (Basel) | year= 2020 | volume= 8 | issue= 2 | pages=  | pmid=32512846 | doi=10.3390/healthcare8020157 | pmc=7349802 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=32512846  }} </ref>


==References==
==References==

Latest revision as of 11:06, 17 June 2021

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]

Acrodermatitis chronica atrophicans Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating Acrodermatitis chronica atrophicans from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Acrodermatitis chronica atrophicans history and symptoms On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Acrodermatitis chronica atrophicans history and symptoms

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Acrodermatitis chronica atrophicans history and symptoms

CDC on Acrodermatitis chronica atrophicans history and symptoms

Acrodermatitis chronica atrophicans history and symptoms in the news

Blogs on Acrodermatitis chronica atrophicans history and symptoms

Directions to Hospitals Treating Type page name here

Risk calculators and risk factors for Acrodermatitis chronica atrophicans history and symptoms

Overview

History of tick bite, erythema migrans or other symptoms of lyme disease, and rheumatological symptoms have been presented in patients with acrodermatitis chronica atrophicans. Since there could be several years between the tick bite and development of skin lesions, absence of tick bite in patients' history never exclude the diagnosis. Symptoms and different forms of skin involvement in acrodermatitis chronica atrophicans are dependent to duration of the disease. Symptoms, such as sclerotic skin changes, pain and burning, edema and constitutional symptoms have been observed in acrodermatitis chronica atrophicans. Half of patients with acrodermatitis chronica atrophicans experience symptoms of peripheral neuropathy, such as paresthesia and hypesthesia. Symptoms of peripheral neuropathy can occure at the exact site of acrodermatitis chronica atrophicans's lesion or at other sites. Involvement of lower limb is more common compared to the upper limb. In some cases episodic knee joint effusion has been observed.

History and Symptoms

History

The following are some of the common findings in patients' history:[1][2][3][4]

Symptoms

References

  1. ↑ 1.0 1.1 Asbrink E, Hovmark A, Olsson I (1986). "Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients". Zentralbl Bakteriol Mikrobiol Hyg A. 263 (1–2): 253–61. doi:10.1016/s0176-6724(86)80128-6. PMID 3577484.
  2. ↑ Asbrink E, Hovmark A, Hederstedt B (1984). "The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer". Acta Derm Venereol. 64 (6): 506–12. PMID 6084922.
  3. ↑ 3.0 3.1 3.2 3.3 Ogrinc K, Maraspin V, Lusa L, Cerar Kišek T, Ružić-Sabljić E, Strle F (2021). "Acrodermatitis chronica atrophicans: clinical and microbiological characteristics of a cohort of 693 Slovenian patients". J Intern Med. doi:10.1111/joim.13266. PMID 33550695 Check |pmid= value (help).
  4. ↑ "StatPearls". 2021. PMID 33085436 Check |pmid= value (help).
  5. ↑ Kaminsky, Anne-Laure; Maisonobe, Thierry; Lenglet, Timothée; Psimaras, Dimitri; Debs, Rabab; Viala, Karine (2020). "Confirmed cases of Neuroborreliosis with involvement of peripheral nervous system". Medicine. 99 (40): e21986. doi:10.1097/MD.0000000000021986. ISSN 0025-7974.
  6. ↑ Muller, Kurt E. (2012). "Damage of Collagen and Elastic Fibres by Borrelia Burgdorferi – Known and New Clinical and Histopathological Aspects". The Open Neurology Journal. 6 (1): 179–186. doi:10.2174/1874205X01206010179. ISSN 1874-205X.
  7. ↑ 7.0 7.1 7.2 Scott JD (2020). "Presentation of Acrodermatitis Chronica Atrophicans Rashes on Lyme Disease Patients in Canada". Healthcare (Basel). 8 (2). doi:10.3390/healthcare8020157. PMC 7349802 Check |pmc= value (help). PMID 32512846 Check |pmid= value (help).

Template:WH Template:WS

Retrieved from "https://www.wikidoc.org/index.php?title=Acrodermatitis_chronica_atrophicans_history_and_symptoms&oldid=1704416"