ADAM9: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Disintegrin and metalloproteinase domain-containing protein 9''' is an [[enzyme]] that in humans is encoded by the ''ADAM9'' [[gene]].<ref name="pmid8647900">{{cite journal | vauthors = Weskamp G, Kratzschmar J, Reid MS, Blobel CP | title = MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains | journal = J Cell Biol | volume = 132 | issue = 4 | pages = 717–26 |date=Jul 1996| pmid = 8647900 | pmc = 2199860 | doi =10.1083/jcb.132.4.717  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8754| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = ADAM metallopeptidase domain 9 (meltrin gamma)
| HGNCid = 216
| Symbol = ADAM9
| AltSymbols =; MCMP; KIAA0021; MDC9; Mltng
| OMIM = 602713
| ECnumber = 
| Homologene = 20824
| MGIid = 105376
| Function = {{GNF_GO|id=GO:0004222 |text = metalloendopeptidase activity}} {{GNF_GO|id=GO:0005178 |text = integrin binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0017124 |text = SH3 domain binding}} {{GNF_GO|id=GO:0019901 |text = protein kinase binding}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005887 |text = integral to plasma membrane}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0006508 |text = proteolysis}} {{GNF_GO|id=GO:0007243 |text = protein kinase cascade}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8754
    | Hs_Ensembl = ENSG00000168615
    | Hs_RefseqProtein = NP_001005845
    | Hs_RefseqmRNA = NM_001005845
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 38973662
    | Hs_GenLoc_end = 39081934
    | Hs_Uniprot = Q13443
    | Mm_EntrezGene = 11502
    | Mm_Ensembl = ENSMUSG00000031555
    | Mm_RefseqmRNA = NM_007404
    | Mm_RefseqProtein = NP_031430
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 8
    | Mm_GenLoc_start = 26415157
    | Mm_GenLoc_end = 26482450
    | Mm_Uniprot = Q3UG15
  }}
}}
'''ADAM metallopeptidase domain 9 (meltrin gamma)''', also known as '''ADAM9''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8754| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes a member of the ADAM ([[a disintegrin and metalloprotease]] domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom [[disintegrin]]s, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with [[SH3 domain]]-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced [[ectodomain]] shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.<ref name="entrez">{{cite web | title = Entrez Gene: ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8754| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
ADAM9 has been shown to [[Protein-protein interaction|interact]] with:
* [[MAD2L2]],<ref name = pmid10527948>{{cite journal | date = Nov 1999 | vauthors = Nelson KK, Schlöndorff J, Blobel CP | title = Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta | journal = Biochem. J. | volume = 343 | issue = Pt 3| pages = 673–80 | pmid = 10527948 | pmc = 1220601 | doi = 10.1042/0264-6021:3430673}}</ref>
* [[SH3GL2]],<ref name = pmid10531379/> and
* [[SNX9]]<ref name = pmid10531379>{{cite journal | date = Oct 1999 | vauthors = Howard L, Nelson KK, Maciewicz RA, Blobel CP | title = Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1 | journal = J. Biol. Chem. | volume = 274 | issue = 44 | pages = 31693–9 | pmid = 10531379 | doi = 10.1074/jbc.274.44.31693}}</ref>
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Mazzocca A, Coppari R, De Franco R, Cho JY, Libermann TA, Pinzani M, Toker A | title = A secreted form of ADAM9 promotes carcinoma invasion through tumor-stromal interactions | journal = Cancer Res. | volume = 65 | issue = 11 | pages = 4728–38 |date=June 2005| pmid = 15930291 | doi = 10.1158/0008-5472.CAN-04-4449 | url = | issn = }}
| citations =
*{{cite journal  | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27–35 |year= 1995 |pmid= 7584026 |doi=10.1093/dnares/1.1.27 |display-authors=etal}}
*{{cite journal | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. |journal=DNA Res. |volume=1 |issue= 1 |pages= 27-35 |year= 1995 |pmid= 7584026 |doi= }}
*{{cite journal  | vauthors=Nomura N, Miyajima N, Sazuka T |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47–56 |year= 1995 |pmid= 7584028 |doi=10.1093/dnares/1.1.47 |display-authors=etal}}
*{{cite journal  | author=Nomura N, Miyajima N, Sazuka T, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1 (supplement). |journal=DNA Res. |volume=1 |issue= 1 |pages= 47-56 |year= 1995 |pmid= 7584028 |doi=  }}
*{{cite journal  | vauthors=McKie N, Dallas DJ, Edwards T |title=Cloning of a novel membrane-linked metalloproteinase from human myeloma cells. |journal=Biochem. J. |volume=318 |issue=  2|pages= 459–62 |year= 1996 |pmid= 8809033 |doi=  | pmc=1217643  |display-authors=etal}}
*{{cite journal  | author=Weskamp G, Krätzschmar J, Reid MS, Blobel CP |title=MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains. |journal=J. Cell Biol. |volume=132 |issue= 4 |pages= 717-26 |year= 1996 |pmid= 8647900 |doi=  }}
*{{cite journal  | vauthors=McKie N, Edwards T, Dallas DJ |title=Expression of members of a novel membrane linked metalloproteinase family (ADAM) in human articular chondrocytes. |journal=Biochem. Biophys. Res. Commun. |volume=230 |issue= 2 |pages= 335–9 |year= 1997 |pmid= 9016778 |doi= 10.1006/bbrc.1996.5957 |display-authors=etal}}
*{{cite journal  | author=McKie N, Dallas DJ, Edwards T, ''et al.'' |title=Cloning of a novel membrane-linked metalloproteinase from human myeloma cells. |journal=Biochem. J. |volume=318 ( Pt 2) |issue=  |pages= 459-62 |year= 1996 |pmid= 8809033 |doi=  }}
*{{cite journal  | vauthors=Izumi Y, Hirata M, Hasuwa H |title=A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. |journal=EMBO J. |volume=17 |issue= 24 |pages= 7260–72 |year= 1999 |pmid= 9857183 |doi= 10.1093/emboj/17.24.7260 | pmc=1171072 |display-authors=etal}}
*{{cite journal  | author=McKie N, Edwards T, Dallas DJ, ''et al.'' |title=Expression of members of a novel membrane linked metalloproteinase family (ADAM) in human articular chondrocytes. |journal=Biochem. Biophys. Res. Commun. |volume=230 |issue= 2 |pages= 335-9 |year= 1997 |pmid= 9016778 |doi= 10.1006/bbrc.1996.5957 }}
*{{cite journal  | vauthors=Roghani M, Becherer JD, Moss ML |title=Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. |journal=J. Biol. Chem. |volume=274 |issue= 6 |pages= 3531–40 |year= 1999 |pmid= 9920899 |doi=10.1074/jbc.274.6.3531  |display-authors=etal}}
*{{cite journal  | author=Izumi Y, Hirata M, Hasuwa H, ''et al.'' |title=A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. |journal=EMBO J. |volume=17 |issue= 24 |pages= 7260-72 |year= 1999 |pmid= 9857183 |doi= 10.1093/emboj/17.24.7260 }}
*{{cite journal  | vauthors=Nelson KK, Schlöndorff J, Blobel CP |title=Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta. |journal=Biochem. J. |volume=343 |issue=  3|pages= 673–80 |year= 2000 |pmid= 10527948 |doi= 10.1042/0264-6021:3430673| pmc=1220601 }}
*{{cite journal  | author=Roghani M, Becherer JD, Moss ML, ''et al.'' |title=Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity. |journal=J. Biol. Chem. |volume=274 |issue= 6 |pages= 3531-40 |year= 1999 |pmid= 9920899 |doi= }}
*{{cite journal  | vauthors=Howard L, Nelson KK, Maciewicz RA, Blobel CP |title=Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. |journal=J. Biol. Chem. |volume=274 |issue= 44 |pages= 31693–9 |year= 1999 |pmid= 10531379 |doi=10.1074/jbc.274.44.31693 }}
*{{cite journal  | author=Nelson KK, Schlöndorff J, Blobel CP |title=Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta. |journal=Biochem. J. |volume=343 Pt 3 |issue=  |pages= 673-80 |year= 2000 |pmid= 10527948 |doi=  }}
*{{cite journal  | vauthors=Zhou M, Graham R, Russell G, Croucher PI |title=MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 574–80 |year= 2001 |pmid= 11162558 |doi= 10.1006/bbrc.2000.4155 }}
*{{cite journal  | author=Howard L, Nelson KK, Maciewicz RA, Blobel CP |title=Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1. |journal=J. Biol. Chem. |volume=274 |issue= 44 |pages= 31693-9 |year= 1999 |pmid= 10531379 |doi=  }}
*{{cite journal  | vauthors=Namba K, Nishio M, Mori K |title=Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes. |journal=Cell. Immunol. |volume=213 |issue= 2 |pages= 104–13 |year= 2002 |pmid= 11831872 |doi= 10.1006/cimm.2001.1873 |display-authors=etal}}
*{{cite journal  | author=Zhou M, Graham R, Russell G, Croucher PI |title=MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin. |journal=Biochem. Biophys. Res. Commun. |volume=280 |issue= 2 |pages= 574-80 |year= 2001 |pmid= 11162558 |doi= 10.1006/bbrc.2000.4155 }}
*{{cite journal  | vauthors=Eto K, Huet C, Tarui T |title=Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions. |journal=J. Biol. Chem. |volume=277 |issue= 20 |pages= 17804–10 |year= 2002 |pmid= 11882657 |doi= 10.1074/jbc.M200086200 |display-authors=etal}}
*{{cite journal  | author=Namba K, Nishio M, Mori K, ''et al.'' |title=Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes. |journal=Cell. Immunol. |volume=213 |issue= 2 |pages= 104-13 |year= 2002 |pmid= 11831872 |doi= 10.1006/cimm.2001.1873 }}
*{{cite journal  | vauthors=Lim JM, Lee JH, Wee WR, Joo CK |title=Downregulated expression of ADAM9 in anterior polar cataracts. |journal=Journal of cataract and refractive surgery |volume=28 |issue= 4 |pages= 697–702 |year= 2002 |pmid= 11955914 |doi=10.1016/S0886-3350(01)01236-6 }}
*{{cite journal  | author=Eto K, Huet C, Tarui T, ''et al.'' |title=Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions. |journal=J. Biol. Chem. |volume=277 |issue= 20 |pages= 17804-10 |year= 2002 |pmid= 11882657 |doi= 10.1074/jbc.M200086200 }}
*{{cite journal  | vauthors=Hotoda N, Koike H, Sasagawa N, Ishiura S |title=A secreted form of human ADAM9 has an alpha-secretase activity for APP. |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 2 |pages= 800–5 |year= 2002 |pmid= 12054541 |doi= 10.1016/S0006-291X(02)00302-9 }}
*{{cite journal  | author=Lim JM, Lee JH, Wee WR, Joo CK |title=Downregulated expression of ADAM9 in anterior polar cataracts. |journal=Journal of cataract and refractive surgery |volume=28 |issue= 4 |pages= 697-702 |year= 2002 |pmid= 11955914 |doi=  }}
*{{cite journal  | vauthors=Amour A, Knight CG, English WR |title=The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. |journal=FEBS Lett. |volume=524 |issue= 1–3 |pages= 154–8 |year= 2002 |pmid= 12135759 |doi=10.1016/S0014-5793(02)03047-8 |display-authors=etal}}
*{{cite journal  | author=Hotoda N, Koike H, Sasagawa N, Ishiura S |title=A secreted form of human ADAM9 has an alpha-secretase activity for APP. |journal=Biochem. Biophys. Res. Commun. |volume=293 |issue= 2 |pages= 800-5 |year= 2002 |pmid= 12054541 |doi= 10.1016/S0006-291X(02)00302-9 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Amour A, Knight CG, English WR, ''et al.'' |title=The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs. |journal=FEBS Lett. |volume=524 |issue= 1-3 |pages= 154-8 |year= 2002 |pmid= 12135759 |doi=  }}
*{{cite journal  | vauthors=Mohan S, Thompson GR, Amaar YG |title=ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts |journal=Biochemistry |volume=41 |issue= 51 |pages= 15394–403 |year= 2003 |pmid= 12484779 |doi=10.1021/bi026458q |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Asai M, Hattori C, Szabó B |title=Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 1 |pages= 231–5 |year= 2003 |pmid= 12535668 |doi=10.1016/S0006-291X(02)02999-6 |display-authors=etal}}
*{{cite journal  | author=Mohan S, Thompson GR, Amaar YG, ''et al.'' |title=ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts. |journal=Biochemistry |volume=41 |issue= 51 |pages= 15394-403 |year= 2003 |pmid= 12484779 |doi=  }}
*{{cite journal  | vauthors=O'Shea C, McKie N, Buggy Y |title=Expression of ADAM-9 mRNA and protein in human breast cancer |journal=Int. J. Cancer |volume=105 |issue= 6 |pages= 754–61 |year= 2003 |pmid= 12767059 |doi= 10.1002/ijc.11161 |display-authors=etal}}
*{{cite journal  | author=Asai M, Hattori C, Szabó B, ''et al.'' |title=Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase. |journal=Biochem. Biophys. Res. Commun. |volume=301 |issue= 1 |pages= 231-5 |year= 2003 |pmid= 12535668 |doi=  }}
*{{cite journal  | vauthors=Grützmann R, Lüttges J, Sipos B |title=ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma |journal=Br. J. Cancer |volume=90 |issue= 5 |pages= 1053–8 |year= 2004 |pmid= 14997207 |doi= 10.1038/sj.bjc.6601645  | pmc=2409625 |display-authors=etal}}
*{{cite journal  | author=O'Shea C, McKie N, Buggy Y, ''et al.'' |title=Expression of ADAM-9 mRNA and protein in human breast cancer. |journal=Int. J. Cancer |volume=105 |issue= 6 |pages= 754-61 |year= 2003 |pmid= 12767059 |doi= 10.1002/ijc.11161 }}
*{{cite journal  | author=Grützmann R, Lüttges J, Sipos B, ''et al.'' |title=ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. |journal=Br. J. Cancer |volume=90 |issue= 5 |pages= 1053-8 |year= 2004 |pmid= 14997207 |doi= 10.1038/sj.bjc.6601645 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
==External links==
{{WikiDoc Sources}}
* [http://AtlasGeneticsOncology.org/Genes/ADAM9ID573ch8p11.html ADAM9] on the [[Atlas of Genetics and Cytogenetics in Oncology and Haematology|Atlas of Genetics and Oncology]]
* {{UCSC gene info|ADAM9}}
 
{{Metalloproteinases}}
 
[[Category:Peptidase]]
[[Category:EC 3.4.24]]
 
 
{{gene-8-stub}}

Latest revision as of 17:48, 29 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

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Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Disintegrin and metalloproteinase domain-containing protein 9 is an enzyme that in humans is encoded by the ADAM9 gene.[1][2]

Function

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.[2]

Interactions

ADAM9 has been shown to interact with:

References

  1. ↑ Weskamp G, Kratzschmar J, Reid MS, Blobel CP (Jul 1996). "MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains". J Cell Biol. 132 (4): 717–26. doi:10.1083/jcb.132.4.717. PMC 2199860. PMID 8647900.
  2. ↑ 2.0 2.1 "Entrez Gene: ADAM9 ADAM metallopeptidase domain 9 (meltrin gamma)".
  3. ↑ Nelson KK, Schlöndorff J, Blobel CP (Nov 1999). "Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta". Biochem. J. 343 (Pt 3): 673–80. doi:10.1042/0264-6021:3430673. PMC 1220601. PMID 10527948.
  4. ↑ 4.0 4.1 Howard L, Nelson KK, Maciewicz RA, Blobel CP (Oct 1999). "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1". J. Biol. Chem. 274 (44): 31693–9. doi:10.1074/jbc.274.44.31693. PMID 10531379.

Further reading

External links


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