2C-T-8: Difference between revisions

Jump to navigation Jump to search
m (Protected "2C-T-8": Protecting pages from unwanted edits ([edit=sysop] (indefinite) [move=sysop] (indefinite)))
 
m (Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}))
 
Line 52: Line 52:


==Reference==
==Reference==
{{reflist}}
{{reflist|2}}


==External links==
==External links==

Latest revision as of 13:48, 4 September 2012


2C-T-8
Chemical name (2-{4-[(cyclopropylmethyl)thio]-2,5-dimethoxyphenyl}ethanamine
Chemical formula C14H21NO2S
Molecular mass 267.387 g/mol
Melting point ?
CAS numbers 207740-27-0
SMILES COc2cc(SCC1CC1)c(cc2CCN)OC
Chemical structure of 2C-T-8
File:2C-T-8-3d-sticks.png

2C-T-8 is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen.

Chemistry

The full name of the chemical is 2,5-dimethoxy-4-cyclopropylmethylthiophenethylamine. The compound is reported to have a bad taste and smell.

Effects

In his book PIHKAL (Phenethylamines I Have Known and Loved), Shulgin lists the dosage range as 30 to 50 mg. 2C-T-8 is generally taken orally, and effects typically last 10 to 15 hours. Experiences have varied between insight and creativity at low doses to hypersensitivity and paranoia at higher doses. A "thinking-connection" that is characteristic of the 2C-T group is evident in this chemical in stark contrast to the "pure euphoria" of phenethylamines such as MDMA.[1]

Legality

2C-T-8 is unscheduled and uncontrolled in the United States, but possession and sales of 2C-T-8 will probably be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7. However, 2C-T-8, unlike many other phenethylamines has not been sold by internet retailers. In the wake of Operation Web Tryp in July 2004, the issue of possession and sales of 2C-T-8 and other similar chemicals will probably be resolved in the courtroom as will the fate of this rare but unique psychedelic. There have been no reported deaths from 2C-T-8.

Pharmacology

The mechanism that produces 2C-T-8’s hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

Dangers

The toxicity of 2C-T-8 is not well documented. 2C-T-8 is somewhat less potent than 2C-T-7, but it may be expected that at higher doses it would display similar toxicity to that of other phenethylamines of the 2C-T family. Other phenethylamine derivatives substituted with an alkylthio group at the 4 position such as 2C-T-7 and 4-MTA are known to act as selective monoamine oxidase A inhibitors, a side effect which can lead to lethal serotonin syndrome when they are combined with stimulant drugs.

There have been no confirmed deaths due to 2C-T-8[citation needed], though this may in part be due to its rarity and limited usage. Of the 2C-T family, there have been a few confirmed deaths due to 2C-T-7, which involved either insufflating large (30mg+) doses[1][2] and in one case an unknown oral dose was combined with 200mg MDMA[3].

Popularity

2C-T-8 is unknown on the black market. Limited accounts of 2C-T-8 can be found in the book PiHKAL.

Reference

External links

Template:Hallucinogen-stub

Template:Hallucinogenic phenethylamines Template:PiHKAL

Template:WikiDoc Sources