Patent foramen ovale platypnoea orthodeoxia syndrome

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Patent Foramen Ovale Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [3]

Overview

The platypnea–orthodeoxia syndrome is characterized by subjective dyspnoea and objective hypoxemia on assuming an upright posture. The syndrome can be seen in inter-atria shunting like patent foramen ovale. In the case of PFO, the upright posture may increase shunting via the redirection of inferior vena cava (IVC) inflow towards the IAS. The syndrome is also seen in conditions like right pneumonectomy, enlarged aortic root and prominent Eustachian valve


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