Pheochromocytoma historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2] Ifrah Fatima, M.B.B.S[3]

Overview

Adrenal pheochromocytoma and its typical clinical presentation was first described by Frankel in 1886. The term pheochromocytoma was coined by Ludwig Pick in 1912. In 1926, Cesar Roux in Switzerland, Charles H. Mayo in the United States, and Isidor Papo in Yugoslavia were the first surgeons to successfully remove pheochromocytomas. An autopsy revealed President Eisenhower had a 1.5-cm pheochromocytoma in the left adrenal gland.

Historical Perspective

Discovery

Landmark Events in the Development of Treatment Strategies

  • In 1926, Cesar Roux in Switzerland, Charles H. Mayo in the United States, and Isidor Papo in Yugoslavia were the first surgeons to successfully remove pheochromocytomas. [2] [3]

Famous Cases

The following are a few famous cases of pheochromocytoma:

References

  1. Else T (2015). "15 YEARS OF PARAGANGLIOMA: Pheochromocytoma, paraganglioma and genetic syndromes: a historical perspective". Endocr Relat Cancer. 22 (4): T147–59. doi:10.1530/ERC-15-0221. PMID 26273101.
  2. Kantorovich V, Pacak K (2010). "Pheochromocytoma and paraganglioma". Prog Brain Res. 182: 343–73. doi:10.1016/S0079-6123(10)82015-1. PMC 4714594. PMID 20541673.
  3. Kudva YC, Sawka AM, Young WF (2003). "Clinical review 164: The laboratory diagnosis of adrenal pheochromocytoma: the Mayo Clinic experience". J Clin Endocrinol Metab. 88 (10): 4533–9. doi:10.1210/jc.2003-030720. PMID 14557417.
  4. Schmoldt A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. PMID doi.org/10.1016/j.amjcard.2006.12.043 Check |pmid= value (help).