Sandbox:Hannan
Myeloproliferative neoplasms (MPN) | Clinical manifestations | Diagnosis | Other features | |||||||||||
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Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | |||||||||
WBCs | RBCs | Platelets | ||||||||||||
Chronic myeloid leukemia
(CML), BCR-ABL1+ |
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Bone marrow aspirate and unilateral biopsy with conventional cytogenetics and flow cytometry | ||||||||||
Leukocytosis | Left shift | Myelocytic bulge | Blasts | Others | ||||||||||
Chronic neutrophilic leukemia (CNL) | ||||||||||||||
Polycythemia vera (PV) | ||||||||||||||
Primary myelofibrosis (PMF)
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Essential thrombocythemia (ET) | ||||||||||||||
Chronic eosinophilic leukemia, not otherwise specified (NOS) | ||||||||||||||
MPN, unclassifiable | ||||||||||||||
Mastocytosis |
Other myeloid neoplasm and acute leukemia | Clinical manifestations | Diagnosis | Other features | ||||
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Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | ||
Myeloid/lymphoid neoplasms with eosinophilia and rearrangement of
PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2
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Myelodysplastic/myeloproliferative neoplasms (MDS/MPN)
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Myelodysplastic syndromes (MDS)
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Acute myeloid leukemia (AML) and related neoplasms
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Blastic plasmacytoid dendritic cell neoplasm | |||||||
Acute leukemias of ambiguous lineage
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B-lymphoblastic leukemia/lymphoma
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T-lymphoblastic leukemia/lymphoma
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