Parotitis differential diagnosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Differentiating Parotitis from Other Diseases
Parotitis must be differentiated from the following diseases:
| Disease | Findings |
|---|---|
| Retropharyngeal abscess | Presents with neck pain, stiff neck, torticollis and may include enlarged cervical lymph nodes, fever, malaise, stridor, and barking cough. Requires tonsillectomy and use of antibiotics.[1] |
| Angioneurotic edema | Presents with swelling of the dermis, subcutaneous, mucosa and submucosal tissues. Can occur in the upper respiratory system and result in stridor and respiratory arrest, requiring emergency treatment. Acquired angioneurotic edema results from an allergic reaction and be treated with epinephrine.[2] |
| Typhoid fever | Presents with fever, headache, rash, gastrointestinal symptoms, with lymphadenopathy, relative bradycardia, cough and leucopenia and sometimes sore throat. Blood and stool culture can confirm the presence of the causative bacteria. |
| Malaria | Presents with acute fever, headache and sometimes diarrhea (children). A blood smears must be examined for malaria parasites. The presence of parasites does not exclude a concurrent viral infection. An antimalarial should be prescribed as an empiric therapy. |
| Lassa fever | Disease onset is usually gradual, with fever, sore throat, cough, pharyngitis, and facial edema in the later stages. Inflammation and exudation of the pharynx and conjunctiva are common. |
| Yellow fever and other Flaviviridae | Present with hemorrhagic complications. Epidemiological investigation may reveal a pattern of disease transmission by an insect vector. Virus isolation and serological investigation serves to distinguish these viruses. Confirmed history of previous yellow fever vaccination will rule out yellow fever. |
| Others | Viral hepatitis, leptospirosis, rheumatic fever, typhus, and mononucleosis can produce signs and symptoms that may be confused with Ebola in the early stages of infection. |
References
- ↑ Craig FW, Schunk JE (2003). "Retropharyngeal abscess in children: clinical presentation, utility of imaging, and current management". Pediatrics. 111 (6 Pt 1): 1394–8. PMID 12777558.
- ↑ Cicardi M, Zanichelli A (2010). "Acquired angioedema". Allergy Asthma Clin Immunol. 6 (1): 14. doi:10.1186/1710-1492-6-14. PMC 2925362. PMID 20667117.