Extramammary Paget's disease other diagnostic studies
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Differentiating Extramammary Paget's disease from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Other Diagnostic Studies
Biopsy
The diagnosis of EMPD requires a high degree of clinical suspicion which should be followed by skin biopsy and pathologic correlation. Skin biopsy to evaluate possible EMPD in patients in whom ongoing therapy is ineffective should be performed. As there are several other genital skin diseases that may appear similar, skin biopsy of the lesion is performed to get an accurate diagnosis of extramammary Paget disease. The presence of Paget cells along with other histological findings confirms diagnosis. To distinguish Paget's disease from early melanoma, special stains may be necessary. See extramammary Paget disease pathology. Because EMPD extends beyond the visibly involved margins, involved skin should be examined by using transverse frozen sections or serial vertical sections.
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