Seminoma laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Laboratory findings consistent with the diagnosis of seminoma include Complete blood count (CBC), white blood cells, red blood cells, and platelets. Kidney function tests is used before and after orchiectomy. Serum tumor marker tests are generally used to check the response to cancer treatment. The following tumor markers may be measured for testicular seminoma.Laboratory findings consistent with the diagnosis of seminoma include abnormal serum tumor marker levels (LDH, HCG). Some patients with seminoma may have elevated concentration of LDH. Among some patients with seminoma may have elevated concentration of human chorionic gonadotropin (hCG). Blood tests may detect the presence of placental alkaline phosphatase (PLAP) among 50% of patients with seminoma.

Laboratory Findings

Complete Blood Count

Complete blood count (CBC) measures the number and quality of white blood cells, red blood cells, and platelets.

Blood Chemistry Tests

Tumor Marker Tests

  • Serum tumor marker tests are generally used to check the response to cancer treatment. The following tumor markers may be measured for testicular seminoma.

References

  1. Milose JC, Filson CP, Weizer AZ, Hafez KS, Montgomery JS (December 2011). "Role of biochemical markers in testicular cancer: diagnosis, staging, and surveillance". Open Access J Urol. 4: 1–8. doi:10.2147/OAJU.S15063. PMC 3818947. PMID 24198649.
  2. Lempiäinen A, Sankila A, Hotakainen K, Haglund C, Blomqvist C, Stenman UH (July 2014). "Expression of human chorionic gonadotropin in testicular germ cell tumors". Urol. Oncol. 32 (5): 727–34. doi:10.1016/j.urolonc.2013.11.007. PMID 24502963.
  3. Koshida K, Uchibayashi T, Yamamoto H, Hirano K (January 1996). "Significance of placental alkaline phosphatase (PLAP) in the monitoring of patients with seminoma". Br J Urol. 77 (1): 138–42. PMID 8653285.

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