Red eye resident survival guide (pediatrics): Difference between revisions

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==Overview==
==Overview==
[[Chest pain|Red eye]] is defined as a [[Discomfort|symptom of red eye]] as the major clinical finding. A detailed history, baseline [[ophthalmological]] tests, and accompanying manifestations can narrow down the differential diagnosis. The duration and laterality of symptoms (uni- vs. bilateral) and the intensity of [[pain]]<ref name="AguileraChen2016">{{cite journal|last1=Aguilera|first1=Zenia P.|last2=Chen|first2=Pauline L.|title=Eye Pain in Children|journal=Pediatrics in Review|volume=37|issue=10|year=2016|pages=418–425|issn=0191-9601|doi=10.1542/pir.2015-0096}}</ref> are the main [[criteria]] allowing the differentiation of non-critical changes that can be cared for by a [[General practitioners|general practitioner]] from diseases calling for elective referral to an [[ophthalmologist]] and eye emergencies requiring urgent [[ophthalmic]] surgery.<ref name="pmid28530180">Frings A, Geerling G, Schargus M (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28530180 Red Eye: A Guide for Non-specialists.] ''Dtsch Arztebl Int'' 114 (17):302-312. [http://dx.doi.org/10.3238/arztebl.2017.0302 DOI:10.3238/arztebl.2017.0302] PMID: [https://pubmed.gov/: 28530180 : 28530180]</ref><ref name="pmid20082509">Cronau H, Kankanala RR, Mauger T (2010) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=20082509 Diagnosis and management of red eye in primary care.] ''Am Fam Physician'' 81 (2):137-44. PMID: [https://pubmed.gov/PMID: 20082509 PMID: 20082509]</ref>
[[Chest pain|Red eye]] is defined as a [[Discomfort|symptom of red eye]] as the major clinical finding. A detailed history, baseline [[ophthalmological]] tests, and accompanying manifestations can narrow down the differential diagnosis. The duration and laterality of symptoms (uni- vs. bilateral) and the intensity of [[pain]] are the main [[criteria]] allowing the differentiation of non-critical changes that can be cared for by a [[General practitioners|general practitioner]] from diseases calling for elective referral to an [[ophthalmologist]] and eye emergencies requiring urgent [[ophthalmic]] surgery.


[[Red eye]] is one of the most common [[ophthalmologic]] conditions in the primary care setting. [[Inflammation]] of almost any part of the eye, including the [[lacrimal glands]] and [[eyelids]], or faulty tear film can lead to [[red eye]]. [[Primary care physician|Primary care]] physicians often effectively manage [[red eye]], although knowing when to refer patients to an [[ophthalmologist]] is crucial.
[[Red eye]] is one of the most common [[ophthalmologic]] conditions in the primary care setting. [[Inflammation]] of almost any part of the eye, including the [[lacrimal glands]] and [[eyelids]], or faulty tear film can lead to [[red eye]]. [[Primary care physician|Primary care]] physicians often effectively manage [[red eye]], although knowing when to refer patients to an [[ophthalmologist]] is crucial.
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==Causes==
==Causes==
===Life Threatening Causes===
===Life Threatening Causes===
Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.<ref name="pmidPMID: 16564769">{{cite journal| author=Wirbelauer C| title=Management of the red eye for the primary care physician. | journal=Am J Med | year= 2006 | volume= 119 | issue= 4 | pages= 302-6 | pmid=PMID: 16564769 | doi=10.1016/j.amjmed.2005.07.065 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16564769  }}</ref>
Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.


*[[globe ruptures]] or perforations
*[[globe ruptures]] or perforations
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*'''Carotid–cavernous sinus fistula'''
*'''Carotid–cavernous sinus fistula'''


===Common Causes<ref name="pmid285301802">Frings A, Geerling G, Schargus M (2017) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=28530180 Red Eye: A Guide for Non-specialists.] ''Dtsch Arztebl Int'' 114 (17):302-312. [http://dx.doi.org/10.3238/arztebl.2017.0302 DOI:10.3238/arztebl.2017.0302] PMID: [https://pubmed.gov/: 28530180 : 28530180]</ref><ref name="pmid27304768">Pflipsen M, Massaquoi M, Wolf S (2016) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=27304768 Evaluation of the Painful Eye.] ''Am Fam Physician'' 93 (12):991-8. PMID: [https://pubmed.gov/PMID: 27304768 PMID: 27304768]</ref><ref name="pmid24852155">Wong MM, Anninger W (2014) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=24852155 The pediatric red eye.] ''Pediatr Clin North Am'' 61 (3):591-606. [http://dx.doi.org/10.1016/j.pcl.2014.03.011 DOI:10.1016/j.pcl.2014.03.011] PMID: [https://pubmed.gov/PMID: 24852155 PMID: 24852155]</ref><ref name="pmid16564769">Wirbelauer C (2006) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=16564769 Management of the red eye for the primary care physician.] ''Am J Med'' 119 (4):302-6. [http://dx.doi.org/10.1016/j.amjmed.2005.07.065 DOI:10.1016/j.amjmed.2005.07.065] PMID: [https://pubmed.gov/PMID: 16564769 PMID: 16564769]</ref><ref name="IsmailAdel2020">{{cite journal|last1=Ismail|first1=M.|last2=Adel|first2=A.|title=Prediction of
===Common Causes<ref name="RainsburyCambridge2016">{{cite journal|last1=Rainsbury|first1=Paul G|last2=Cambridge|first2=Kate|last3=Selby|first3=Stephen|last4=Lochhead|first4=Jonathan|title=Red eyes in children: red flags and a case to learn from|journal=British Journal of General Practice|volume=66|issue=653|year=2016|pages=633–634|issn=0960-1643|doi=10.3399/bjgp16X688309}}</ref>===
α
-decay chains and cluster radioactivity of
121300–304
and  
122302–306
isotopes using the double-folding potential|journal=Physical Review C|volume=101|issue=2|year=2020|issn=2469-9985|doi=10.1103/PhysRevC.101.024607}}</ref>===


==== infectious<ref name="Høvding2008">{{cite journal|last1=Høvding|first1=Gunnar|title=Acute bacterial conjunctivitis|journal=Acta Ophthalmologica|volume=86|issue=1|year=2008|pages=5–17|issn=1755375X|doi=10.1111/j.1600-0420.2007.01006.x}}</ref>====
==== infectious====


*[[Bacterial conjunctivitis]]
*[[Bacterial conjunctivitis]]
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==FIRE: Focused Initial Rapid Evaluation==
==FIRE: Focused Initial Rapid Evaluation==
Patients with the [[primary symptom]] of a [[red eye]] are commonly seen in [[pediatric]] [[primary care]] clinics. The differential diagnoses of a [[red eye]] are broad, but with a succinct history and [[physical examination]], the diagnosis can be readily identified in many patients. Identifying conditions that threaten vision and understanding the [[urgency]] of referral to an [[ophthalmologist]] is paramount. Some [[systemic diseases]] such as [[leukemia]], [[sarcoidosis]], and [[juvenile idiopathic arthritis]] can present with the chief symptom of a [[red eye]]. Finally, [[trauma]], ranging from mild to severe, often [[precipitates]] an office visit with a [[red eye]], and thus understanding the signs that raise concern for a [[ruptured globe]] is essential. In the [[primary care]] setting, with a focused [[History and Physical examination|history]], a few simple examination techniques, and an appreciation of the differential diagnosis, one can feel confident in managing patients with acute [[red eyes]].<ref name="pmid26796813">Petersen EE, Staples JE, Meaney-Delman D, Fischer M, Ellington SR, Callaghan WM | display-authors=etal (2016) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=26796813 Interim Guidelines for Pregnant Women During a Zika Virus Outbreak--United States, 2016.] ''MMWR Morb Mortal Wkly Rep'' 65 (2):30-3. [http://dx.doi.org/10.15585/mmwr.mm6502e1 DOI:10.15585/mmwr.mm6502e1] PMID: [https://pubmed.gov/PMID: 26796813 PMID: 26796813]</ref><ref name="SinghGalvis2018">{{cite journal|last1=Singh|first1=Gagandeep|last2=Galvis|first2=Alvaro|last3=Das|first3=Samrat|title=Case 1: Eye Discharge in a 10-day-old Neonate Born by Cesarean Delivery|journal=Pediatrics in Review|volume=39|issue=4|year=2018|pages=210–210|issn=0191-9601|doi=10.1542/pir.2016-0090}}</ref><ref name="AzariBarney2013">{{cite journal|last1=Azari|first1=Amir A.|last2=Barney|first2=Neal P.|title=Conjunctivitis|journal=JAMA|volume=310|issue=16|year=2013|pages=1721|issn=0098-7484|doi=10.1001/jama.2013.280318}}</ref><ref name="BieloryO’Brien2012">{{cite journal|last1=Bielory|first1=Brett P.|last2=O’Brien|first2=Terrence P.|last3=Bielory|first3=Leonard|title=Management of seasonal allergic conjunctivitis: guide to therapy|journal=Acta Ophthalmologica|volume=90|issue=5|year=2012|pages=399–407|issn=1755375X|doi=10.1111/j.1755-3768.2011.02272.x}}</ref><ref name="CheungChee2012">{{cite journal|last1=Cheung|first1=Chui Ming Gemmy|last2=Chee|first2=Soon-Phaik|title=Posterior Scleritis in Children: Clinical Features and Treatment|journal=Ophthalmology|volume=119|issue=1|year=2012|pages=59–65|issn=01616420|doi=10.1016/j.ophtha.2011.09.030}}</ref><ref name="GuptaDhawan2010">{{cite journal|last1=Gupta|first1=Noopur|last2=Dhawan|first2=Anuradha|last3=Beri|first3=Sarita|last4=D'souza|first4=Pamela|title=Clinical spectrum of pediatric blepharokeratoconjunctivitis|journal=Journal of American Association for Pediatric Ophthalmology and Strabismus|volume=14|issue=6|year=2010|pages=527–529|issn=10918531|doi=10.1016/j.jaapos.2010.09.013}}</ref><ref name="Kaufman2011">{{cite journal|last1=Kaufman|first1=Herbert E|title=Adenovirus advances: new diagnostic and therapeutic options|journal=Current Opinion in Ophthalmology|volume=22|issue=4|year=2011|pages=290–293|issn=1040-8738|doi=10.1097/ICU.0b013e3283477cb5}}</ref><ref name="KhajaPogrebniak2015">{{cite journal|last1=Khaja|first1=Wassia A.|last2=Pogrebniak|first2=Alexander E.|last3=Bolling|first3=James P.|title=Combined orbital proptosis and exudative retinal detachment as initial manifestations of acute myeloid leukemia|journal=Journal of American Association for Pediatric Ophthalmology and Strabismus|volume=19|issue=5|year=2015|pages=479–482|issn=10918531|doi=10.1016/j.jaapos.2015.05.018}}</ref><ref name="pmid24906667">LaMattina K, Thompson L (2014) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=24906667 Pediatric conjunctivitis.] ''Dis Mon'' 60 (6):231-8. [http://dx.doi.org/10.1016/j.disamonth.2014.03.002 DOI:10.1016/j.disamonth.2014.03.002] PMID: [https://pubmed.gov/PMID: 24906667 PMID: 24906667]</ref><ref name="pmid10">Schmoldt A, Benthe HF, Haberland G (1975) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10 Digitoxin metabolism by rat liver microsomes.] ''Biochem Pharmacol'' 24 (17):1639-41. PMID: [https://pubmed.gov/https://doi.org/10.3109/02713683.2014.964419 https://doi.org/10.3109/02713683.2014.964419]</ref><ref name="pmid15993231">Rose PW, Harnden A, Brueggemann AB, Perera R, Sheikh A, Crook D | display-authors=etal (2005) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=15993231 Chloramphenicol treatment for acute infective conjunctivitis in children in primary care: a randomised double-blind placebo-controlled trial.] ''Lancet'' 366 (9479):37-43. [http://dx.doi.org/10.1016/S0140-6736(05)66709-8 DOI:10.1016/S0140-6736(05)66709-8] PMID: [https://pubmed.gov/PMID: 15993231 PMID: 15993231]</ref><ref name="pmid26517055">Tappeiner C, Klotsche J, Schenck S, Niewerth M, Minden K, Heiligenhaus A (2015) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=26517055 Temporal change in prevalence and complications of uveitis associated with juvenile idiopathic arthritis:data from a cross-sectional analysis of a prospective nationwide study.] ''Clin Exp Rheumatol'' 33 (6):936-44. PMID: [https://pubmed.gov/PMID: 26517055 PMID: 26517055]</ref><ref name="pmid22071229">Teo L, Mehta JS, Htoon HM, Tan DT (2012) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=22071229 Severity of pediatric blepharokeratoconjunctivitis in Asian eyes.] ''Am J Ophthalmol'' 153 (3):564-570.e1. [http://dx.doi.org/10.1016/j.ajo.2011.08.037 DOI:10.1016/j.ajo.2011.08.037] PMID: [https://pubmed.gov/PMID: 22071229 PMID: 22071229]</ref><ref name="pmid23177360">Wieringa WG, Wieringa JE, ten Dam-van Loon NH, Los LI (2013) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=23177360 Visual outcome, treatment results, and prognostic factors in patients with scleritis.] ''Ophthalmology'' 120 (2):379-86. [http://dx.doi.org/10.1016/j.ophtha.2012.08.005 DOI:10.1016/j.ophtha.2012.08.005] PMID: [https://pubmed.gov/PMID: 23177360 PMID: 23177360]</ref><ref name="pmid21705879">Wong VW, Lai TY, Chi SC, Lam DS (2011) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=21705879 Pediatric ocular surface infections: a 5-year review of demographics, clinical features, risk factors, microbiological results, and treatment.] ''Cornea'' 30 (9):995-1002. [http://dx.doi.org/10.1097/ICO.0b013e31820770f4 DOI:10.1097/ICO.0b013e31820770f4] PMID: [https://pubmed.gov/PMID: 21705879 PMID: 21705879]</ref>
Patients with the [[primary symptom]] of a [[red eye]] are commonly seen in [[pediatric]] [[primary care]] clinics. The differential diagnoses of a [[red eye]] are broad, but with a succinct history and [[physical examination]], the diagnosis can be readily identified in many patients. Identifying conditions that threaten vision and understanding the [[urgency]] of referral to an [[ophthalmologist]] is paramount. Some [[systemic diseases]] such as [[leukemia]], [[sarcoidosis]], and [[juvenile idiopathic arthritis]] can present with the chief symptom of a [[red eye]]. Finally, [[trauma]], ranging from mild to severe, often [[precipitates]] an office visit with a [[red eye]], and thus understanding the signs that raise concern for a [[ruptured globe]] is essential. In the [[primary care]] setting, with a focused [[History and Physical examination|history]], a few simple examination techniques, and an appreciation of the differential diagnosis, one can feel confident in managing patients with acute [[red eyes]].


==Complete Diagnostic Approach==
==Complete Diagnostic Approach==
localised, diffused and perikeratic injection. <ref name="pmidPMID: 18506971">{{cite journal| author=Sauer A, Speeg-Schatz C, Bourcier T| title=[Red eye in children]. | journal=Rev Prat | year= 2008 | volume= 58 | issue= 4 | pages= 353-7 | pmid=PMID: 18506971 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18506971  }}</ref>
localised, diffused and perikeratic injection.  


Shown below is an algorithm summarizing the diagnosis of <nowiki>[[red eye]]</nowiki> according the the [ Nelson Essentials of Pediatrics .] guidelines. <ref name="pmid12592117">Teoh DL, Reynolds S (2003) [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12592117 Diagnosis and management of pediatric conjunctivitis.] ''Pediatr Emerg Care'' 19 (1):48-55. [http://dx.doi.org/10.1097/00006565-200302000-00014 DOI:10.1097/00006565-200302000-00014] PMID: [https://pubmed.gov/PMID: 12592117 PMID: 12592117]</ref>
Shown below is an algorithm summarizing the diagnosis of <nowiki>[[red eye]]</nowiki> according the the [ Nelson Essentials of Pediatrics .] guidelines.  
<br />
<br />
{| class="wikitable"
{| class="wikitable"
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Shown below is an algorithm summarizing the treatment of <nowiki>[[Red eye ]]</nowiki> according the the [American family physician ] guidelines.
Shown below is an algorithm summarizing the treatment of <nowiki>[[Red eye ]]</nowiki> according the the [American family physician ] guidelines.


Good hygiene, such as meticulous hand washing, is important in decreasing the spread of acute viral conjunctivitis.<ref name="pmidPMID: 179708232">{{cite journal| author=Høvding G| title=Acute bacterial conjunctivitis. | journal=Acta Ophthalmol | year= 2008 | volume= 86 | issue= 1 | pages= 5-17 | pmid=PMID: 17970823 | doi=10.1111/j.1600-0420.2007.01006.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17970823  }}</ref><ref name="pmidPMID: 10922425">{{cite journal| author=Leibowitz HM| title=The red eye. | journal=N Engl J Med | year= 2000 | volume= 343 | issue= 5 | pages= 345-51 | pmid=PMID: 10922425 | doi=10.1056/NEJM200008033430507 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10922425  }}</ref>
Good hygiene, such as meticulous hand washing, is important in decreasing the spread of acute viral conjunctivitis.


Any ophthalmic antibiotic may be considered for the treatment of acute bacterial conjunctivitis because they have similar cure rates.<ref name="pmidPMID: 2540136">{{cite journal| author=| title=Trimethoprim-polymyxin B sulphate ophthalmic ointment versus chloramphenicol ophthalmic ointment in the treatment of bacterial conjunctivitis--a review of four clinical studies. The Trimethoprim-Polymyxin B Sulphate Ophthalmic Ointment Study Group. | journal=J Antimicrob Chemother | year= 1989 | volume= 23 | issue= 2 | pages= 261-6 | pmid=PMID: 2540136 | doi=10.1093/jac/23.2.261 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2540136  }}</ref> <ref name="pmidPMID: 17652708">{{cite journal| author=Protzko E, Bowman L, Abelson M, Shapiro A, AzaSite Clinical Study Group| title=Phase 3 safety comparisons for 1.0% azithromycin in polymeric mucoadhesive eye drops versus 0.3% tobramycin eye drops for bacterial conjunctivitis. | journal=Invest Ophthalmol Vis Sci | year= 2007 | volume= 48 | issue= 8 | pages= 3425-9 | pmid=PMID: 17652708 | doi=10.1167/iovs.06-1413 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17652708  }}</ref>
Any ophthalmic antibiotic may be considered for the treatment of acute bacterial conjunctivitis because they have similar cure rates.  


Mild allergic conjunctivitis may be treated with an over-the-counter antihistamine/vasoconstrictor agent, or with a more effective second-generation topical histamine H1 receptor antagonist.<ref name="pmidPMID: 30366797">{{cite journal| author=Varu DM, Rhee MK, Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ | display-authors=etal| title=Conjunctivitis Preferred Practice Pattern®. | journal=Ophthalmology | year= 2019 | volume= 126 | issue= 1 | pages= P94-P169 | pmid=PMID: 30366797 | doi=10.1016/j.ophtha.2018.10.020 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30366797  }}</ref>
Mild allergic conjunctivitis may be treated with an over-the-counter antihistamine/vasoconstrictor agent, or with a more effective second-generation topical histamine H1 receptor antagonist.


<ref name="pmidPMID: 30366798">{{cite journal| author=Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ, Lin A, Rhee MK | display-authors=etal| title=Dry Eye Syndrome Preferred Practice Pattern®. | journal=Ophthalmology | year= 2019 | volume= 126 | issue= 1 | pages= P286-P334 | pmid=PMID: 30366798 | doi=10.1016/j.ophtha.2018.10.023 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30366798  }}</ref>Anti-inflammatory agents (e.g., topical cyclosporine [Restasis]), topical corticosteroids, and systemic omega-3 fatty acids are appropriate therapies for moderate dry eye.
Anti-inflammatory agents (e.g., topical cyclosporine [Restasis]), topical corticosteroids, and systemic omega-3 fatty acids are appropriate therapies for moderate dry eye.


Patients with chronic blepharitis who do not respond adequately to eyelid hygiene and topical antibiotics may benefit from an oral tetracycline or doxycycline.
Patients with chronic blepharitis who do not respond adequately to eyelid hygiene and topical antibiotics may benefit from an oral tetracycline or doxycycline.
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{{familytree/end}}
{{familytree/end}}


==Do's<ref name="BalHollingworth2005">{{cite journal|last1=Bal|first1=Sharon K|last2=Hollingworth|first2=Gary R|title=Red eye|journal=BMJ|volume=331|issue=7514|year=2005|pages=438|issn=0959-8138|doi=10.1136/bmj.331.7514.438}}</ref>==
==Do's==


** Your most important task is to detect potentially serious ocular presentations for immediate referral of the patient to an [[ophthalmologist]] and treatment. Conditions requiring referral to an [[ophthalmologist]] are [[orbital cellulitis]], [[hyphaema]], [[scleritis]], [[iritis]] or [[uveitis]], acute angle closure [[glaucoma]], and corneal abrasions (unless very superficial).
** Your most important task is to detect potentially serious ocular presentations for immediate referral of the patient to an [[ophthalmologist]] and treatment. Conditions requiring referral to an [[ophthalmologist]] are [[orbital cellulitis]], [[hyphaema]], [[scleritis]], [[iritis]] or [[uveitis]], acute angle closure [[glaucoma]], and corneal abrasions (unless very superficial).
** Use caution when prescribing steroids: you should exclude the possibility of herpetic keratitis.
** Use caution when prescribing steroids: you should exclude the possibility of herpetic keratitis.
** Ocular [[pain]]<ref name="AguileraChen20162">{{cite journal|last1=Aguilera|first1=Zenia P.|last2=Chen|first2=Pauline L.|title=Eye Pain in Children|journal=Pediatrics in Review|volume=37|issue=10|year=2016|pages=418–425|issn=0191-9601|doi=10.1542/pir.2015-0096}}</ref> and change in [[vision]] are two extremely specific warning signs of eye pathology, and unless you are absolutely certain of a [[benign]] diagnosis you must refer him for [[Ophthalmologicals|ophthalmological]] assessment if he has these.
** Ocular [[pain]] and change in [[vision]] are two extremely specific warning signs of eye pathology, and unless you are absolutely certain of a [[benign]] diagnosis you must refer him for [[Ophthalmologicals|ophthalmological]] assessment if he has these.


==Don'ts==
==Don'ts==
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Revision as of 12:13, 9 August 2020


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Eman Alademi, M.D.[2]

Red eye resident survival guide (pediatrics) Microchapters
Overview
Causes
FIRE
Diagnosis
Treatment
Do's
Don'ts

Overview

Red eye is defined as a symptom of red eye as the major clinical finding. A detailed history, baseline ophthalmological tests, and accompanying manifestations can narrow down the differential diagnosis. The duration and laterality of symptoms (uni- vs. bilateral) and the intensity of pain are the main criteria allowing the differentiation of non-critical changes that can be cared for by a general practitioner from diseases calling for elective referral to an ophthalmologist and eye emergencies requiring urgent ophthalmic surgery.

Red eye is one of the most common ophthalmologic conditions in the primary care setting. Inflammation of almost any part of the eye, including the lacrimal glands and eyelids, or faulty tear film can lead to red eye. Primary care physicians often effectively manage red eye, although knowing when to refer patients to an ophthalmologist is crucial.

Causes

Life Threatening Causes

Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.

Common Causes[1]

infectious

noninfectious

FIRE: Focused Initial Rapid Evaluation

Patients with the primary symptom of a red eye are commonly seen in pediatric primary care clinics. The differential diagnoses of a red eye are broad, but with a succinct history and physical examination, the diagnosis can be readily identified in many patients. Identifying conditions that threaten vision and understanding the urgency of referral to an ophthalmologist is paramount. Some systemic diseases such as leukemia, sarcoidosis, and juvenile idiopathic arthritis can present with the chief symptom of a red eye. Finally, trauma, ranging from mild to severe, often precipitates an office visit with a red eye, and thus understanding the signs that raise concern for a ruptured globe is essential. In the primary care setting, with a focused history, a few simple examination techniques, and an appreciation of the differential diagnosis, one can feel confident in managing patients with acute red eyes.

Complete Diagnostic Approach

localised, diffused and perikeratic injection.

Shown below is an algorithm summarizing the diagnosis of [[red eye]] according the the [ Nelson Essentials of Pediatrics .] guidelines.

Age Group Common Etiology
Neonates* < 24 hrs Chemical conjunctivitis
< 1 week Neisseria gonorrhea
1-2 wks Chlamydia trachomatis
Infants and Toddlers Without otitis Haemolphilus. influenzae, Streptococcus pneumoniae
With otitis H. influenzae
School Age Children 1-5 years Herpes simplex virusVaricella-zoster
School Age Children and Adolescents Viral conjunctivitisAllergic conjunctivtis
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Treatment

Shown below is an algorithm summarizing the treatment of [[Red eye ]] according the the [American family physician ] guidelines.

Good hygiene, such as meticulous hand washing, is important in decreasing the spread of acute viral conjunctivitis.

Any ophthalmic antibiotic may be considered for the treatment of acute bacterial conjunctivitis because they have similar cure rates.

Mild allergic conjunctivitis may be treated with an over-the-counter antihistamine/vasoconstrictor agent, or with a more effective second-generation topical histamine H1 receptor antagonist.

Anti-inflammatory agents (e.g., topical cyclosporine [Restasis]), topical corticosteroids, and systemic omega-3 fatty acids are appropriate therapies for moderate dry eye.

Patients with chronic blepharitis who do not respond adequately to eyelid hygiene and topical antibiotics may benefit from an oral tetracycline or doxycycline.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Do's

    • Your most important task is to detect potentially serious ocular presentations for immediate referral of the patient to an ophthalmologist and treatment. Conditions requiring referral to an ophthalmologist are orbital cellulitis, hyphaema, scleritis, iritis or uveitis, acute angle closure glaucoma, and corneal abrasions (unless very superficial).
    • Use caution when prescribing steroids: you should exclude the possibility of herpetic keratitis.
    • Ocular pain and change in vision are two extremely specific warning signs of eye pathology, and unless you are absolutely certain of a benign diagnosis you must refer him for ophthalmological assessment if he has these.

Don'ts

  • The content in this section is in bullet points.


References

  1. Rainsbury, Paul G; Cambridge, Kate; Selby, Stephen; Lochhead, Jonathan (2016). "Red eyes in children: red flags and a case to learn from". British Journal of General Practice. 66 (653): 633–634. doi:10.3399/bjgp16X688309. ISSN 0960-1643.


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