Sandbox:Hannan: Difference between revisions
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Hannan Javed (talk | contribs) No edit summary |
Hannan Javed (talk | contribs) No edit summary |
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|Chronic myeloid leukemia | |Chronic myeloid leukemia | ||
(CML), BCR-ABL1+ | (CML), BCR-ABL1+ | ||
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* <small>50% of patients are asymptomatic</small> | * <small>50% of patients are asymptomatic</small> | ||
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* <small>priapism</small> | * <small>priapism</small> | ||
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* <small>absolute leukocytosis (median of 100,000/µL)</small> | |||
* <small>left shift</small> | |||
* <small>classic myelocyte bulge ( myelocytes > metamyelocytes on the blood smear)</small> | |||
* <small>blasts usually <2%</small> | |||
* <small>absolute basophilia is almost always present</small> | |||
* <small>absolute eosinophilia in 90% of patients</small> | |||
* <small>monocytosis is often present, but generally not an increased monocyte percentage</small> | |||
* <small>absolute monocytosis is seen more often in cases with a p190 BCR-ABL</small> | |||
* <small>Platelet count is usually normal or elevated</small> | |||
* <small>thrombocytopenia indicates advanced stage or an alternative diagnosis</small> | |||
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<references /> |
Revision as of 15:53, 15 January 2019
Myeloproliferative neoplasms (MPN) | Clinical manifestations | Diagnosis | Other features | ||||
---|---|---|---|---|---|---|---|
Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | ||
Chronic myeloid leukemia
(CML), BCR-ABL1+ |
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Chronic neutrophilic leukemia (CNL) | |||||||
Polycythemia vera (PV) | |||||||
Primary myelofibrosis (PMF)
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Essential thrombocythemia (ET) | |||||||
Chronic eosinophilic leukemia, not otherwise specified (NOS) | |||||||
MPN, unclassifiable | |||||||
Mastocytosis |
Other myeloid neoplasm and acute leukemia | Clinical manifestations | Diagnosis | Other features | ||||
---|---|---|---|---|---|---|---|
Symptoms | Physical examination | Lab findings | Bone marrow biopsy | Gold standard | Other investigations | ||
Myeloid/lymphoid neoplasms with eosinophilia and rearrangement of
PDGFRA, PDGFRB, or FGFR1, or with PCM1-JAK2
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Myelodysplastic/myeloproliferative neoplasms (MDS/MPN)
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Myelodysplastic syndromes (MDS)
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Acute myeloid leukemia (AML) and related neoplasms
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Blastic plasmacytoid dendritic cell neoplasm | |||||||
Acute leukemias of ambiguous lineage
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B-lymphoblastic leukemia/lymphoma
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T-lymphoblastic leukemia/lymphoma
|