Barrett's esophagus natural history, complications and prognosis: Difference between revisions

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==Natural History, Complications, and Prognosis==
==Natural History, Complications, and Prognosis==
===Natural History===
===Natural History===
An increased risk of [[esophageal cancer]] is present. Follow-up [[endoscopy]] to look for [[dysplasia]] or [[cancer]] is often advised.
An increased risk of [[esophageal cancer]]<ref name="pmid21995385">{{cite journal| author=Hvid-Jensen F, Pedersen L, Drewes AM, Sørensen HT, Funch-Jensen P| title=Incidence of adenocarcinoma among patients with Barrett's esophagus. | journal=N Engl J Med | year= 2011 | volume= 365 | issue= 15 | pages= 1375-83 | pmid=21995385 | doi=10.1056/NEJMoa1103042 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21995385  }} </ref> is present. Follow-up [[endoscopy]] to look for [[dysplasia]] or [[cancer]] is often advised.
*The symptoms of [[Barrett's esophagus]] usually develop in the fifth/sixth decade of life, and start with symptoms of [[GERD]] such as [[heartburn]], [[regurgitation]] and [[dysphagia]].  
*The symptoms of [[Barrett's esophagus]] usually develop in the fifth/sixth decade of life, and start with symptoms of [[GERD]] such as [[heartburn]], [[regurgitation]] and [[dysphagia]].  
*The symptoms of (disease name) typically develop ___ years after exposure to ___.  
*The symptoms of (disease name) typically develop ___ years after exposure to ___.  

Revision as of 15:35, 2 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]

Overview

Common complications of Barrett's esophagus include esophageal carcinoma[1], esophageal stricture[2] and esophageal ulcers[2].

Natural History, Complications, and Prognosis

Natural History

An increased risk of esophageal cancer[1] is present. Follow-up endoscopy to look for dysplasia or cancer is often advised.

  • The symptoms of Barrett's esophagus usually develop in the fifth/sixth decade of life, and start with symptoms of GERD such as heartburn, regurgitation and dysphagia.
  • The symptoms of (disease name) typically develop ___ years after exposure to ___.
  • If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

Progression

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
  • Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. 1.0 1.1 Hvid-Jensen F, Pedersen L, Drewes AM, Sørensen HT, Funch-Jensen P (2011). "Incidence of adenocarcinoma among patients with Barrett's esophagus". N Engl J Med. 365 (15): 1375–83. doi:10.1056/NEJMoa1103042. PMID 21995385.
  2. 2.0 2.1 Milind R, Attwood SE (2012). "Natural history of Barrett's esophagus". World J Gastroenterol. 18 (27): 3483–91. doi:10.3748/wjg.v18.i27.3483. PMC 3400849. PMID 22826612.
  3. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMID 21376940. Unknown parameter |month= ignored (help)

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