Barrett's esophagus laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2] Amresh Kumar MD [3]
Overview
Laboratory findings consistent with diagnosis of Barrett's esophagus is the presence of acidic reflux in the esophagus through the ambulatory reflux monitoring.
Laboratory Findings
The laboratory findings for Barrett's esophagus are as follows:[1]
Helicobacter Pylori
- Test for H. Pylori infection should be done
- Changes often arise secondary to Helicobacter pylori infection[2]
Ambulatory reflux monitoring
- Ambulatory reflux monitoring is recommended by the American College of Gastroenterology (ACG) as the only laboratory test to determine the presence of acidic reflux in the esophagus.[3]
- Indications of ambulatory reflux monitoring include the following:[4]
- Ambulatory reflux monitoring is performed in either two ways which include:
- Telemetry capsule (48 hours monitoring)
- Transnasal catheter (24 hours monitoring)
References
- ↑ Booth CL, Thompson KS (2012). "Barrett's esophagus: A review of diagnostic criteria, clinical surveillance practices and new developments". J Gastrointest Oncol. 3 (3): 232–42. doi:10.3978/j.issn.2078-6891.2012.028. PMC 3418534. PMID 22943014.
- ↑ Goldblum JR (2002). "The significance and etiology of intestinal metaplasia of the esophagogastric junction". Ann Diagn Pathol. 6 (1): 67–73. PMID 11842382.
- ↑ Katz PO, Gerson LB, Vela MF (2013). "Guidelines for the diagnosis and management of gastroesophageal reflux disease". Am J Gastroenterol. 108 (3): 308–28, quiz 329. doi:10.1038/ajg.2012.444. PMID 23419381.
- ↑ Katz PO, Gerson LB, Vela MF (2013). "Guidelines for the diagnosis and management of gastroesophageal reflux disease". Am J Gastroenterol. 108 (3): 308–28, quiz 329. doi:10.1038/ajg.2012.444. PMID 23419381.