Hypoparathyroidism historical perspective: Difference between revisions

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*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
*In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
* In 1909, William George MacCallum and Carl Voegtlin, demonstrated association between [[parathyroid gland]], [[calcium]], and [[tetany]].<ref name="pmid19867238">{{cite journal |vauthors=Maccallum WG, Voegtlin C |title=ON THE RELATION OF TETANY TO THE PARATHYROID GLANDS AND TO CALCIUM METABOLISM |journal=J. Exp. Med. |volume=11 |issue=1 |pages=118–51 |year=1909 |pmid=19867238 |pmc=2124703 |doi= |url=}}</ref>
* In 1909, William George MacCallum and Carl Voegtlin, demonstrated association between [[parathyroid gland]], [[calcium]], and [[tetany]].<ref name="pmid19867238">{{cite journal |vauthors=Maccallum WG, Voegtlin C |title=ON THE RELATION OF TETANY TO THE PARATHYROID GLANDS AND TO CALCIUM METABOLISM |journal=J. Exp. Med. |volume=11 |issue=1 |pages=118–51 |year=1909 |pmid=19867238 |pmc=2124703 |doi= |url=}}</ref>
* In 1959, Howard Rasmussen and Lyman C. Craig at the Rockefeller Institute for Medical Research purified [[parathyroid hormone]].<ref name="RasmussenCraig1959">{{cite journal|last1=Rasmussen|first1=Howard|last2=Craig|first2=Lyman C.|title=PURIFICATION OF PARATHYROID HORMONE BY USE OF COUNTERCURRENT DISTRIBUTION|journal=Journal of the American Chemical Society|volume=81|issue=18|year=1959|pages=5003–5003|issn=0002-7863|doi=10.1021/ja01527a066}}</ref> They also isolated the active [[polypeptide]] (parathormone B) from bovine [[parathyroid gland]] and gave its tentative formula in 1961.<ref>{{Cite journal||last1=Rasmussen|first1=Howard|last2=Craig|first2=Lyman C.|title = Isolation of a Parathyroid Polypeptide from Acetic Acid Extracts of Bovine Parathyroid Glands|volume = 236| number = 4|pages = 1083-1086|year = 1961|URL = http://www.jbc.org/content/236/4/1083.short|journal = {Journal of Biological Chemistry}}</ref>


==Outbreaks==
==Outbreaks==

Revision as of 13:29, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Historical Perspective

Discovery

  • [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
  • The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
  • In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
  • In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
  • In 1909, William George MacCallum and Carl Voegtlin, demonstrated association between parathyroid gland, calcium, and tetany.[1]
  • In 1959, Howard Rasmussen and Lyman C. Craig at the Rockefeller Institute for Medical Research purified parathyroid hormone.[2] They also isolated the active polypeptide (parathormone B) from bovine parathyroid gland and gave its tentative formula in 1961.[3]

Outbreaks

  • There have been several outbreaks of [disease name], which are summarized below:

Landmark Events in the Development of Treatment Strategies

  • In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
  • In 1925, James Bertram Collip along with Douglous B Leitch treated tetany with the help of parathyroid extract. They names the extract as Parathyrin.[4]

Impact on Cultural History

Famous Cases

References

  1. Maccallum WG, Voegtlin C (1909). "ON THE RELATION OF TETANY TO THE PARATHYROID GLANDS AND TO CALCIUM METABOLISM". J. Exp. Med. 11 (1): 118–51. PMC 2124703. PMID 19867238.
  2. Rasmussen, Howard; Craig, Lyman C. (1959). "PURIFICATION OF PARATHYROID HORMONE BY USE OF COUNTERCURRENT DISTRIBUTION". Journal of the American Chemical Society. 81 (18): 5003–5003. doi:10.1021/ja01527a066. ISSN 0002-7863.
  3. Rasmussen, Howard; Craig, Lyman C. (1961). "Isolation of a Parathyroid Polypeptide from Acetic Acid Extracts of Bovine Parathyroid Glands". {Journal of Biological Chemistry. 236 (4): 1083–1086.
  4. Collip JB, Leitch DB (1925). "A Case of Tetany treated with Parathyrin". Can Med Assoc J. 15 (1): 59–60. PMC 1707993. PMID 20315252.

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