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==Overview==
==Overview==
Laboratory findings consistent with the diagnosis of myelofibrosis include [[anemia|decreased red blood cells]], [[normochromic]] normocytic [[anemia]], tear-drop shaped RBCs, [[thrombocytopenia]], and raised levels of [[lactate dehydrogenase]].<ref name=wikidiagn1osismf1>Diagnosis of myelofibrosis. Wikipedia 2016. https://en.wikipedia.org/wiki/Myelofibrosis. Accessed on March 8, 2016</ref><ref name=cancercaidiopathicmyelofibrosisdx1>Diagnosis of idiopathic myelofibrosis. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/idiopathic-myelofibrosis/?region=on. Accessed on March 9, 2016</ref>


==Laboratory Tests==
==Laboratory Tests==

Revision as of 18:54, 14 March 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

Laboratory findings consistent with the diagnosis of myelofibrosis include decreased red blood cells, normochromic normocytic anemia, tear-drop shaped RBCs, thrombocytopenia, and raised levels of lactate dehydrogenase.[1][2]

Laboratory Tests

Laboratory findings consistent with the diagnosis of myelofibrosis include:[1][2]

Complete Blood Count

Peripheral Blood Smear

  • Presence of nucleated red blood cells suggests that immature cells are being released into the bloodstream in response to a very high demand for the bone marrow to produce new red blood cells.

Complete Metabolic Panel

Leukocyte Alkaline Phosphatase Test (LAP Test)

References

  1. 1.0 1.1 Diagnosis of myelofibrosis. Wikipedia 2016. https://en.wikipedia.org/wiki/Myelofibrosis. Accessed on March 8, 2016
  2. 2.0 2.1 Diagnosis of idiopathic myelofibrosis. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/leukemia/leukemia/idiopathic-myelofibrosis/?region=on. Accessed on March 9, 2016


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