Myelofibrosis MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
MRI may be helpful in the diagnosis of myelofibrosis. Findings on MRI suggestive of myelofibrosis include diffuse decrease in bone marrow signal intensity.
MRI
- MRI may be helpful in the diagnosis of myelofibrosis and can be useful in evaluating the stage and the progression of disease.
- Findings on MRI suggestive of myelofibrosis include:
- Diffuse decrease in bone marrow signal intensity[1][2][3]
- Very low, mainly homogeneous signal on both T1- and T2-weighted images[4]
- Foci of extramedullary hematopoiesis (EMH) involving the spine manifest as heterogeneous and predominantly hyperintense masses
- Foci of intracranial extramedullary hematopoiesis (EMH) manifest as masses of variable signal intensity[5]
Images
References
- ↑ Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016
- ↑ Ueda F, Takashima T, Suzuki M, Kadoya M (1994). "MR diagnosis of myelofibrosis". Radiat Med. 12 (3): 135–7. PMID 7972898.
- ↑ Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME (1986). "MR imaging in myelofibrosis". J Comput Assist Tomogr. 10 (4): 634–6. PMID 3734203.
- ↑ Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J (1999). "Imaging findings in patients with myelofibrosis". Eur Radiol. 9 (7): 1366–75. doi:10.1007/s003300050850. PMID 10460376.
- ↑ Koch BL, Bisset GS, Bisset RR, Zimmer MB (June 1994). "Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation". AJR Am J Roentgenol. 162 (6): 1419–20. doi:10.2214/ajr.162.6.8192010. PMID 8192010.