Sporotrichosis medical therapy: Difference between revisions

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|Pulmonary
|Pulmonary
|Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.]
|Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.]
|Deoxycholate amphotericin B [3-5 mg/day], followed by itraconazole upon symptom resolution
|Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution
|Treat less sever cases with a 12 month regimen of itraconazole.
|Treat less sever cases with a 12 month regimen of itraconazole.
|-
|-
|Meningeal
|Meningeal
|
|Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.]
|
|Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution
|
|Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary.
|-
|-
|Dissimated
|Dissimated

Revision as of 15:43, 12 January 2016

Sporotrichosis Microchapters

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Differentiating Sporotrichosis from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alison Leibowitz [2]

Treatment

Form Primary Line of Treatment Alternative Treatment Remarks/Other
Uncomplicated cutaneous Itraconazole [200 mg/day] Itraconazole [200 b.i.d.],

terbinafine [500 b.i.d.],

SSKI [increasing doses],

fluconazole [400-800 mg/day], or

local hyperthermia

Continue treatment for 2-4 weeks after lesions resolve.
Osteoarticular Itraconazole [200 mg b.i.d.] Limposomal amphotericin B [3-5 mg/kg/day] or deoxycholate amphotericin B [0.7-1 mg/kg/day] until symptom resolution For a total of 12 months, switch to itraconazole after resolution/end of treatment.
Pulmonary Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution Treat less sever cases with a 12 month regimen of itraconazole.
Meningeal Limposomal amphotericin B [3-5 mg/kg/day], followed by itraconazole [200 mg b.i.d.] Deoxycholate amphotericin B [0.7-1 mg/kg/day], followed by itraconazole upon symptom resolution Precise length of amphotericin B treatment varies. Suppressive treatment with itraconazole is necessary.
Dissimated
Sporotrichosis in pregnant women
Sporotrichosis in Children

References