Rhabdomyosarcoma pathophysiology: Difference between revisions
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====Alveolar Rhabdomyosarcoma==== | ====Alveolar Rhabdomyosarcoma==== | ||
Characterized by Alveolus-like pattern: | Characterized by Alveolus-like pattern: | ||
*Fibrous septae lined by tumor cells. | *Fibrous [[septae]] lined by tumor cells. | ||
**Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space. | **Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space. | ||
**Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma. | **Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma. | ||
Rhabdomyoblasts: Essentially diagnostic cells with [[ | Rhabdomyoblasts: Essentially diagnostic cells with [[Nucleus|eccentric nucleus]] and Moderate amount of intensely eosinophilic cytoplasm. | ||
==References== | ==References== |
Revision as of 14:54, 1 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Microscopic Pathology
Characteristic features on microscopic analysis are variable depending on the chondrosarcoma subtype:
Alveolar Rhabdomyosarcoma
Characterized by Alveolus-like pattern:
- Fibrous septae lined by tumor cells.
- Cells may "fall-off" the septa, i.e. be detached/scattered in the alveolus-like space.
- Space between fibrous septae may be filled with tumor, called solid variant of alveolar rhabdomyosarcoma.
Rhabdomyoblasts: Essentially diagnostic cells with eccentric nucleus and Moderate amount of intensely eosinophilic cytoplasm.