VR-CHOP regimen: Difference between revisions

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{{PAGENAME}} refers to a regimen consisting of [[Bortezomib|velcade (bortezomib)]], [[rituximab]], [[cyclophosphamide]], [[Doxorubicin|hydroxydaunorubicin (doxorubicin)]], [[Vincristine|oncovin (Vincristine)]], [[prednisone]] used to treat previously untreated [[diffuse large B-cell lymphoma]] and [[mantle cell lymphoma]].<ref name="pmid21189393">{{cite journal| author=Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM et al.| title=Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. | journal=J Clin Oncol | year= 2011 | volume= 29 | issue= 6 | pages= 690-7 | pmid=21189393 | doi=10.1200/JCO.2010.31.1142 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21189393 }} </ref>
{{PAGENAME}} refers to a regimen consisting of [[Bortezomib|velcade (bortezomib)]], [[rituximab]], [[cyclophosphamide]], [[Doxorubicin|hydroxydaunorubicin (doxorubicin)]], [[Vincristine|oncovin (Vincristine)]], [[prednisone]] used to treat previously untreated [[diffuse large B-cell lymphoma]] and [[mantle cell lymphoma]].<ref name="pmid21189393">{{cite journal| author=Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM et al.| title=Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. | journal=J Clin Oncol | year= 2011 | volume= 29 | issue= 6 | pages= 690-7 | pmid=21189393 | doi=10.1200/JCO.2010.31.1142 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21189393 }} </ref>
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==Regimen==
==Regimen==
{{chemo|V|Velcade (Bortezomib)}}
{{chemo|V|Velcade (Bortezomib)}}
{{chemo|R|Rituximab}}
{{chemo|R|Rituximab}}
{{chemo|C|Cyclophosphamide}}
{{chemo|C|Cyclophosphamide}}
{{chemo|H|Hydroxydaunorubicin (Doxorubicin)}}
{{chemo|H|Hydroxydaunorubicin (Doxorubicin)}}


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==Indications==
==Indications==
*[[Diffuse large B-cell lymphoma]] and [[Mantle cell lymphoma]].<ref name="pmid21189393">{{cite journal| author=Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM et al.| title=Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. | journal=J Clin Oncol | year= 2011 | volume= 29 | issue= 6 | pages= 690-7 | pmid=21189393 | doi=10.1200/JCO.2010.31.1142 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21189393  }} </ref>
*[[Diffuse large B-cell lymphoma]] and [[Mantle cell lymphoma]].<ref name="pmid21189393">{{cite journal| author=Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM et al.| title=Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma. | journal=J Clin Oncol | year= 2011 | volume= 29 | issue= 6 | pages= 690-7 | pmid=21189393 | doi=10.1200/JCO.2010.31.1142 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21189393  }} </ref>



Revision as of 13:22, 30 March 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Overview

VR-CHOP regimen refers to a regimen consisting of velcade (bortezomib), rituximab, cyclophosphamide, hydroxydaunorubicin (doxorubicin), oncovin (Vincristine), prednisone used to treat previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma.[1] .

Regimen

VVelcade (Bortezomib)

RRituximab

CCyclophosphamide

HHydroxydaunorubicin (Doxorubicin)

OOncovin (Vincristine)

PPrednisone

Indications

References

  1. 1.0 1.1 Ruan J, Martin P, Furman RR, Lee SM, Cheung K, Vose JM; et al. (2011). "Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma". J Clin Oncol. 29 (6): 690–7. doi:10.1200/JCO.2010.31.1142. PMID 21189393.