Hepatitis E medical therapy: Difference between revisions

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As no specific therapy is capable of altering the course of acute hepatitis E infection, [[prevention]] is the most effective approach against the disease.  Hospitalization is required for [[fulminant hepatitis]] and should be considered for [[infected]] pregnant women.<ref name=WHO>{{cite web | title = Hepatitis E | url = http://www.who.int/csr/disease/hepatitis/HepatitisE_whocdscsredc2001_12.pdf }}</ref><ref>{{cite book | last = Fields | first = Bernard | title = Fields virology | publisher = Wolters Kluwer Health/Lippincott Williams & Wilkins | location = Philadelphia | year = 2013 | isbn = 9781451105636 }}</ref><ref>{{cite book | last = LastName | first = FirstName | title = Lippincott's guide to infectious diseases | publisher = Wolters Kluwer/Lippincott Williams & Wilkins Health | location = Philadelphia | year = 2011 | isbn = 1605479756 }}</ref>
As no specific therapy is capable of altering the course of acute hepatitis E infection, [[prevention]] is the most effective approach against the disease.  Hospitalization is required for [[fulminant hepatitis]] and should be considered for [[infected]] pregnant women.<ref name=WHO>{{cite web | title = Hepatitis E | url = http://www.who.int/csr/disease/hepatitis/HepatitisE_whocdscsredc2001_12.pdf }}</ref><ref>{{cite book | last = Fields | first = Bernard | title = Fields virology | publisher = Wolters Kluwer Health/Lippincott Williams & Wilkins | location = Philadelphia | year = 2013 | isbn = 9781451105636 }}</ref><ref>{{cite book | last = LastName | first = FirstName | title = Lippincott's guide to infectious diseases | publisher = Wolters Kluwer/Lippincott Williams & Wilkins Health | location = Philadelphia | year = 2011 | isbn = 1605479756 }}</ref>
===Acute Hepatitis E===
===Acute Hepatitis E===
The majority of hepatitis E cases are self-limited, resolving without requiring therapy. However, patients with pre-existing liver conditions may require treatment with [[ribavirin]].
The majority of hepatitis E cases are self-limited, resolving without requiring therapy. However, patients with pre-existing liver conditions may require treatment with [[ribavirin]].<ref name="pmid21281681">{{cite journal| author=Péron JM, Dalton H, Izopet J, Kamar N| title=Acute autochthonous hepatitis E in western patients with underlying chronic liver disease: a role for ribavirin? | journal=J Hepatol | year= 2011 | volume= 54 | issue= 6 | pages= 1323-4; author reply 1324-5 | pmid=21281681 | doi=10.1016/j.jhep.2011.01.009 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21281681  }} </ref><ref name="pmid21764632">{{cite journal| author=Gerolami R, Borentain P, Raissouni F, Motte A, Solas C, Colson P| title=Treatment of severe acute hepatitis E by ribavirin. | journal=J Clin Virol | year= 2011 | volume= 52 | issue= 1 | pages= 60-2 | pmid=21764632 | doi=10.1016/j.jcv.2011.06.004 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21764632  }} </ref>
===Chronic Hepatitis E===
===Chronic Hepatitis E===



Revision as of 14:11, 25 August 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]

Overview

Medical Therapy

As no specific therapy is capable of altering the course of acute hepatitis E infection, prevention is the most effective approach against the disease. Hospitalization is required for fulminant hepatitis and should be considered for infected pregnant women.[1][2][3]

Acute Hepatitis E

The majority of hepatitis E cases are self-limited, resolving without requiring therapy. However, patients with pre-existing liver conditions may require treatment with ribavirin.[4][5]

Chronic Hepatitis E

References

  1. "Hepatitis E" (PDF).
  2. Fields, Bernard (2013). Fields virology. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. ISBN 9781451105636.
  3. LastName, FirstName (2011). Lippincott's guide to infectious diseases. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health. ISBN 1605479756.
  4. Péron JM, Dalton H, Izopet J, Kamar N (2011). "Acute autochthonous hepatitis E in western patients with underlying chronic liver disease: a role for ribavirin?". J Hepatol. 54 (6): 1323–4, author reply 1324-5. doi:10.1016/j.jhep.2011.01.009. PMID 21281681.
  5. Gerolami R, Borentain P, Raissouni F, Motte A, Solas C, Colson P (2011). "Treatment of severe acute hepatitis E by ribavirin". J Clin Virol. 52 (1): 60–2. doi:10.1016/j.jcv.2011.06.004. PMID 21764632.

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