Alkylglycerone phosphate synthase: Difference between revisions
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'''Alkylglycerone phosphate synthase''' ({{EC number|2.5.1.26}}, ''alkyldihydroxyacetonephosphate synthase'', ''alkyldihydroxyacetone phosphate synthetase'', ''alkyl DHAP synthetase'', ''alkyl-DHAP'', ''dihydroxyacetone-phosphate acyltransferase'', ''DHAP-AT'') is an [[enzyme]] associated with Type 3 [[Rhizomelic chondrodysplasia punctata]].<ref>{{cite journal | title = Alkyldihydroxyacetone- | '''Alkylglycerone phosphate synthase''' ({{EC number|2.5.1.26}}, ''alkyldihydroxyacetonephosphate synthase'', ''alkyldihydroxyacetone phosphate synthetase'', ''alkyl DHAP synthetase'', ''alkyl-DHAP'', ''dihydroxyacetone-phosphate acyltransferase'', ''DHAP-AT'') is an [[enzyme]] associated with Type 3 [[Rhizomelic chondrodysplasia punctata]].<ref>{{cite journal | vauthors = Brown AJ, Snyder F | title = Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism | journal = The Journal of Biological Chemistry | volume = 257 | issue = 15 | pages = 8835–9 | date = August 1982 | pmid = 7096336 }}</ref><ref>{{cite journal | vauthors = Wykle RL, Plantadosi C, Snyder F | title = The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor | journal = The Journal of Biological Chemistry | volume = 247 | issue = 9 | pages = 2944–8 | date = May 1972 | pmid = 4401994 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] | ||
: 1-acyl-glycerone 3-phosphate + a long-chain alcohol <math>\rightleftharpoons</math> an alkyl-glycerone 3-phosphate + a long-chain acid anion | : 1-acyl-glycerone 3-phosphate + a long-chain alcohol <math>\rightleftharpoons</math> an alkyl-glycerone 3-phosphate + a long-chain acid anion | ||
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{{reflist}} | {{reflist}} | ||
==External links== | == External links == | ||
*{{MeshName|Alkylglycerone-phosphate+synthase}} | *{{MeshName|Alkylglycerone-phosphate+synthase}} | ||
Latest revision as of 08:39, 17 February 2018
| alkylglycerone-phosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.26 | ||||||||
| CAS number | 64060-42-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| alkylglycerone phosphate synthase | |
|---|---|
| Identifiers | |
| Symbol | AGPS |
| Entrez | 8540 |
| HUGO | 327 |
| OMIM | 603051 |
| RefSeq | NM_003659 |
| UniProt | O00116 |
| Other data | |
| EC number | 2.5.1.26 |
| Locus | Chr. 2 q31 |
Alkylglycerone phosphate synthase (EC 2.5.1.26, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetone phosphate synthetase, alkyl DHAP synthetase, alkyl-DHAP, dihydroxyacetone-phosphate acyltransferase, DHAP-AT) is an enzyme associated with Type 3 Rhizomelic chondrodysplasia punctata.[1][2] This enzyme catalyses the following chemical reaction
- 1-acyl-glycerone 3-phosphate + a long-chain alcohol <math>\rightleftharpoons</math> an alkyl-glycerone 3-phosphate + a long-chain acid anion
References
- ↑ Brown AJ, Snyder F (August 1982). "Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism". The Journal of Biological Chemistry. 257 (15): 8835–9. PMID 7096336.
- ↑ Wykle RL, Plantadosi C, Snyder F (May 1972). "The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor". The Journal of Biological Chemistry. 247 (9): 2944–8. PMID 4401994.
External links
- Alkylglycerone-phosphate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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