Gallbladder cancer screening: Difference between revisions
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==Overview== | ==Overview== | ||
According to the National Comprehensive Cancer Network (NCCN) guidelines, gallbladder cancer may be diagnosed as an accidental finding in patients who undergo laparoscopic cholecystectomy. | |||
==Screening== | ==Screening== | ||
* According to the NCCN guidelines, screening for gallbladder cancer patients is recommended with endoscopic ultrasongraphy (EUS), computed tomography (CT) , magnetic resonance imaging (MRI) with/without contrast and patients after incidental finding during laparoscopic cholecystectomy patient are recommmends considering staging laparoscopy.<sup> </sup> | |||
=== Ultrasound === | |||
* when gallbladder pathology is suspected ultrasonography is most commonly the first choice for screening. | |||
* Sensitivity and specificity of ultrasound screening is 85% and 80%. | |||
* A High-resolution contrast-enhanced ultrasonography identifies up to 70–90% of polypoid gallbladder lesions.<ref name="pmid21628925">{{cite journal |vauthors=Inui K, Yoshino J, Miyoshi H |title=Diagnosis of gallbladder tumors |journal=Intern. Med. |volume=50 |issue=11 |pages=1133–6 |year=2011 |pmid=21628925 |doi= |url=}}</ref> | |||
* Gallbladder cancer on ultrasound have one of the following feartures<ref name="pmid26421012">{{cite journal |vauthors=Kanthan R, Senger JL, Ahmed S, Kanthan SC |title=Gallbladder Cancer in the 21st Century |journal=J Oncol |volume=2015 |issue= |pages=967472 |year=2015 |pmid=26421012 |pmc=4569807 |doi=10.1155/2015/967472 |url=}}</ref> | |||
** 1) A mass in the gallbladder | |||
** 2) A polyp in the gallbladder | |||
** 3) Asymmetric wall thickening of the gallbladder | |||
* Polyps which are over 1 cm in diameter have higher chance to contain an invasive cancer than smaller ones.<ref name="pmid7572497">{{cite journal |vauthors=Wibbenmeyer LA, Sharafuddin MJ, Wolverson MK, Heiberg EV, Wade TP, Shields JB |title=Sonographic diagnosis of unsuspected gallbladder cancer: imaging findings in comparison with benign gallbladder conditions |journal=AJR Am J Roentgenol |volume=165 |issue=5 |pages=1169–74 |year=1995 |pmid=7572497 |doi=10.2214/ajr.165.5.7572497 |url=}}</ref> | |||
* With Contrast-enhanced ultrasonography gallbladder cancer shows an “eruption sign”<ref name="pmid24959553">{{cite journal |vauthors=Vijayakumar A, Vijayakumar A, Patil V, Mallikarjuna MN, Shivaswamy BS |title=Early diagnosis of gallbladder carcinoma: an algorithm approach |journal=ISRN Radiol |volume=2013 |issue= |pages=239424 |year=2013 |pmid=24959553 |pmc=4045520 |doi=10.5402/2013/239424 |url=}}</ref> | |||
==References== | ==References== | ||
Revision as of 21:13, 18 January 2018
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Gallbladder cancer screening On the Web |
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Risk calculators and risk factors for Gallbladder cancer screening |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
According to the National Comprehensive Cancer Network (NCCN) guidelines, gallbladder cancer may be diagnosed as an accidental finding in patients who undergo laparoscopic cholecystectomy.
Screening
- According to the NCCN guidelines, screening for gallbladder cancer patients is recommended with endoscopic ultrasongraphy (EUS), computed tomography (CT) , magnetic resonance imaging (MRI) with/without contrast and patients after incidental finding during laparoscopic cholecystectomy patient are recommmends considering staging laparoscopy.
Ultrasound
- when gallbladder pathology is suspected ultrasonography is most commonly the first choice for screening.
- Sensitivity and specificity of ultrasound screening is 85% and 80%.
- A High-resolution contrast-enhanced ultrasonography identifies up to 70–90% of polypoid gallbladder lesions.[1]
- Gallbladder cancer on ultrasound have one of the following feartures[2]
- 1) A mass in the gallbladder
- 2) A polyp in the gallbladder
- 3) Asymmetric wall thickening of the gallbladder
- Polyps which are over 1 cm in diameter have higher chance to contain an invasive cancer than smaller ones.[3]
- With Contrast-enhanced ultrasonography gallbladder cancer shows an “eruption sign”[4]
References
- ↑ Inui K, Yoshino J, Miyoshi H (2011). "Diagnosis of gallbladder tumors". Intern. Med. 50 (11): 1133–6. PMID 21628925.
- ↑ Kanthan R, Senger JL, Ahmed S, Kanthan SC (2015). "Gallbladder Cancer in the 21st Century". J Oncol. 2015: 967472. doi:10.1155/2015/967472. PMC 4569807. PMID 26421012.
- ↑ Wibbenmeyer LA, Sharafuddin MJ, Wolverson MK, Heiberg EV, Wade TP, Shields JB (1995). "Sonographic diagnosis of unsuspected gallbladder cancer: imaging findings in comparison with benign gallbladder conditions". AJR Am J Roentgenol. 165 (5): 1169–74. doi:10.2214/ajr.165.5.7572497. PMID 7572497.
- ↑ Vijayakumar A, Vijayakumar A, Patil V, Mallikarjuna MN, Shivaswamy BS (2013). "Early diagnosis of gallbladder carcinoma: an algorithm approach". ISRN Radiol. 2013: 239424. doi:10.5402/2013/239424. PMC 4045520. PMID 24959553.