Plummer-Vinson syndrome causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Causes

The cause of Plummer-Vinson syndrome is unknown; however, iron deficiency anemia, genetic factors and nutritional deficiencies may play a role. Iron deficiency anemia can be due to:

Increased Iron Requirement

Physiological

• Growth
• Pregnancy

Pathological

Blood Loss

• Mensturation
• Gastrointestinal tract (Bleeding from the gastrointestinal tract (ulcers, hemorrhoids, Esophageal varices, The use of aspirin, ibuprofen, or arthritis medicines for a long time, Cancer in the esophagus, stomach, or colon)
  • Food sensitivity
  • Hookworms
• Genitourinary tract
• Respiratory tract (Rarely laryngological bleeding or from the respiratory tract)
• Blood donation

Inadequate Iron Absorption

• Dietary deficiency
• Impaired absorption (Celiac disease, Crohn's disease)
  • Intestinal malabsorption
  • Gastric surgery
  • Hypochorhydria
• Taking too many antacids that contain calcium

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