Plummer-Vinson syndrome epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

Plummer-Vinson syndrome is a rare disease and the data pertaining to its incidence and prevalence is not evidently available. Overall improvement in nutritional status with better medical care has markedly reduced the number of cases of Plummer-Vinson syndrome. However, individuals of any age groups may develop Plummer-Vinson syndrome and it is most commonly seen in the age group of 40-70 years. Plummer-Vinson syndrome usually affects individuals of the caucasian race. Females are commonly affected than males with female to male ratio of 4:1. The majority of Plummer-Vinson syndrome cases are reported in Scandinavian countries or north European countries.

Epidemiology and Demographics

The epidemiology and demographics of Plummer-Vinson syndrome is as below:[1][2][3][4][5][6]

Incidence

Prevalence

Age

  • Patients of all age groups may develop Plummer-Vinson syndrome.
  • In adults, Plummer-Vinson syndrome commonly affects individuals in fourth to seventh decade of life.
  • In children, Plummer-Vinson syndrome commonly affects females in the age group of 10-18 years.

Race

  • Plummer-Vinson syndrome usually affects individuals of the caucasian race.

Gender

  • Women are more commonly affected by Plummer-Vinson syndrome than men.
  • In Plummer-Vinson syndrome the female to male ratio is 4:1.
  • Among women, Plummer-Vinson syndrome is seen commonly in premenopausal and married women (fourth and fifth decade of life).

Region

  • The majority of Plummer-Vinson syndrome cases were reported in Scandinavian countries or north European countries.

References

  1. Mansell NJ, Jani P, Bailey CM (1999). "Plummer-Vinson syndrome--a rare presentation in a child". J Laryngol Otol. 113 (5): 475–6. PMID 10505167.
  2. Novacek G (2006). "Plummer-Vinson syndrome". Orphanet J Rare Dis. 1: 36. doi:10.1186/1750-1172-1-36. PMC 1586011. PMID 16978405.
  3. Naik, Sudhir M; MC, Shivakumar; Appaji, Mohan K; Ravishankara, S; Naik, Sarika S; de Souza, Chris (2011). "A Case of Plummer-Vinson Syndrome Esophageal Web Dysphagia treated by Dilatation with Cuffed Endotracheal Tube". International Journal of Head and Neck Surgery. 2: 161–165. doi:10.5005/jp-journals-10001-1076. ISSN 0975-7899.
  4. Chen TS, Chen PS (1994). "Rise and fall of the Plummer-Vinson syndrome". J. Gastroenterol. Hepatol. 9 (6): 654–8. PMID 7865729.
  5. Wynder, Ernest L.; Hultberg, Sven; Jacobsson, Folke; Bross, Irwin J. (1957). "Environmental factors in cancer of the upper alimentary tract.A swedish study with special reference to plummer-vinson (Paterson-Kelly) syndrome". Cancer. 10 (3): 470–487. doi:10.1002/1097-0142(195705/06)10:3<470::AID-CNCR2820100309>3.0.CO;2-7. ISSN 0008-543X.
  6. Chisholm, M. (1974). "The association between webs, iron and post-cricoid carcinoma". Postgraduate Medical Journal. 50 (582): 215–219. doi:10.1136/pgmj.50.582.215. ISSN 0032-5473.

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