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===Cardioversion upto7 Days===
{{familytree/start}}
{{familytree | | | | | | | | | | | | A01 |-| A02 |-| A03 | | | | |A01=<div style="float: left; text-align: left; padding:1em">'''Confirmed aortic dissection''' <br> ❑ Check whether dissection occurred in ascending aorta </div>|A02=Yes |A03=Consider surgical management}}
{{familytree | | | | | | | | | | | | |!| | | | | | | | | | | | | |}}
{{familytree | | | | | | | | | | | | B01 | | | | | | | | | | | | |B01=No}}
{{familytree | | | | | | | | | | | | |!| | | | | | | | | | | | | |}}
{{familytree | | | | | | | | | | | | C01 | | | | | | | | | | | | |C01=<div style="float: left; text-align: left; padding:1em">❑ Start Medical management </div>}}
{{familytree | | | | | | | | | | | | |!| | | | | | | | | | | | | |}}
{{familytree | | | | | | | | | | | | D01 | | | | | | | | | | | | |D01=<div style="float: left; text-align: left; padding:1em">❑ Check Vitals <br>
:❑ Blood pressure in both arms <br>
:❑ Take the highest reading for treatment or goal therapy <br>
❑ Is patient hemodynamically stable ?</div> }}
{{familytree | | | | | | | | |,|-|-|-|^|-|-|-|-|-|-|-|.| | | | | |}}
{{familytree | | | | | | | | E01 | | | | | | | | | | E02 | | | | |E01=Yes |E02=No}}
{{familytree | | | | | | | | |!| | | | | | | |,|-|-|-|^|-|-|-|.| |}}
{{familytree | | | | | | | | F01 | | | | | | F02 | | | | | | F03 |F01=<div style="float: left; text-align: left; padding:1em">❑ Control rate and pressure<br>
: ❑ I.V [[Beta blockers]] or [[labetalol]]
: ❑ Substitute [[diltiazem]] and [[verapamil]]<br> If [[betablockers]] are contraindicated
----
❑ Goal Heart rate should be 60 beats per minute
----
❑ Pain control<br>
: ❑ Use [[Opiates]]</div> |F02=<div style="float: left; text-align: left; padding:1em"> ❑ '''Type A dissection'''
----
❑ Expedited surgical consultation and consider surgery (Urgent)<br>
❑ Maintain Euvolemic status<br>
: ❑ Intravenous fluid replacement<br>
:❑ Maintain [[mean arterial pressure|mean arterial pressure (MAP)]] of 70 mm of hg<br>
❑ Rule out complications using imaging study<br>
: ❑ [[Cardiac tamponade|Pericardial tamponade]]
: ❑ [[Aortic rupture|Rupture of aorta]]<br>
: ❑ [[Aortic insufficiency]]</div>|F03=<div style="float: left; text-align: left; padding:1em">❑ Type B dissection
----
❑ Intravenous fluid replacement<br>
: ❑ Maintain [[mean arterial pressure|mean arterial pressure (MAP)]] of 70 mm of hg<br>
❑ Start vasopressor if still hypotensive
----
❑ Find out etiology of hypertension
:❑ Imaging to find out contained rupture
:❑ Perform [[Echocardiography|Transthoracic echocardiogram (TTE)]] to assess cardiac function
----
❑ Consider surgical evaluation</div> }}
{{familytree | | | | | | | | |!| | | | | | | |!| | | | | | | |!| |}}
{{familytree | | | | | | | | |!| | | | | | | G01 | | | | | | |!| |G01=<div style="float: left; text-align: left; padding:1em">❑ Can the cause of hypotension respond to surgical management</div>}}
{{familytree | | | | | | | | |!| | | |,|-|-|-|^|-|-|-|.| | | |!| |}}
{{familytree | | | | | | | | H01 |-| H02 | | | | | | H03 |-| H04 |H01=<div style="float: left; text-align: left; padding:1em">❑ Monitor vitals closely
: ❑ Maintain systolic BP <120 mm of Hg</div> |H02=No |H03=Yes |H04=Consider surgical management}}
{{familytree | | | | |,|-|-|-|^|-|-|-|.| | | | | | | | | | | | | |}}
{{familytree | | | | I01 | | | | | | I02 | | | | | | | | | | | | |I01=Yes |I02=No}}
{{familytree | | | | |!| | | | | | | |!| | | | | | | | | | | | | |}}
{{familytree | | | | |!| | | | | | | J01 |-|-|-|-|-| J02 | | | | |J01=<div style="float: left; text-align: left; padding:1em"> ❑ Check whether dissection involves ascending aorta</div> |J02=Yes}}
{{familytree | | | | |!| | | | | | | |!| | | | | | | |!| | | | | |}}
{{familytree | | | | |!| | | | | | | K01 | | | | | | |!| | | | | |K01=No}}
{{familytree | | | | |!| | | | | | | |!| | | | | | | |!| | | | | |}}
{{familytree | | | | |`|-|-| L01 |-|-|'| | | | | | | |!| | | | | |L01=<div style="float: left; text-align: left; padding:1em">❑ Control blood pressure
: ❑ Intravenous vasodilator</div>}}
{{familytree | | | | | | | | |!| | | | | | | | | | | |!| | | | | |}}
{{familytree | | | | | | | | M01 | | | | | | | | | | |!| | | | | |M01=<div style="float: left; text-align: left; padding:1em">❑ Monitor vitals closely
: ❑ Maintain systolic BP <120 mm of Hg</div>}}
{{familytree | | | | | | | | |!| | | | | | | | | | | |!| | | | | |}}
{{familytree | | | | | | | | N01 |-| N02 |-| N03 |-|-|'| | | | | |N01=<div style="float: left; text-align: left; padding:1em">❑ Check for any complications which might require surgery
----
: ❑ Malperfusion
: ❑ Progressing dissection
: ❑ Expansion of aortic aneurysm
: ❑ [[Hypertension causes|Uncontrolled or refractory hypertension]] </div> |N02=Yes|N03=<div style="float: left; text-align: left; padding:1em">❑ Consider surgical management</div>}}
{{familytree | | | | | | | | |!| | | | | | | | | | | | | | | | | |}}
{{familytree | | | | | | | | O01 | | | | | | | | | | | | | | | | |O01=No}}
{{familytree | | | | | | | | |!| | | | | | | | | | | | | | | | | |}}
{{familytree | | | | | | | | P01 | | | | | | | | | | | | | | | | |P01=<div style="float: left; text-align: left; padding:1em">❑ Switch to oral medications <br>
:❑ [[Betablockers]]
:❑ Antihypertensive regimen
----
❑ Follow up in the outpatient</div>}}
{{familytree | | | | | | | | | | | | | | | | | | | | | | | | | | |}}


<table class="wikitable">
==First Initial Rapid Evaluation of Suspected Aortic Dissection==
<tr class="v-firstrow"><th>Drug</th><th>Class of Recommendation/<br>Level of Evidence</th><th> Dosage </th></tr>
Shown below is an algorithm for the First Initial Rapid Evaluation (FIRE) of Aortic dissection.
<tr><th>Agents with proven efficacy</th></tr>
{{familytree/start}}
<tr><td>Dofetilide</td><td>I A</td><td><table class="wikitable">
{{familytree | | | | | | | | | | A01 | | | | | | | | | | |A01=❑ Identify cardinal signs and symptoms that increase the pretest probability of acute aortic rupture }}
<tr class="v-firstrow"><th>Creatinine clearance(ml/min)</th><th>Dose (mg)</th></tr>
{{familytree | | | | | | | | | | |!| | | | | | | | | | | | }}
<tr><td> >60</td><td>500</td></tr>
{{familytree | | | | | | | | | | B01 | | | | | | | | | | |B01=<div style="text-align: left">❑ Sudden onset chest pain (tearing/ripping/sharp or stabbing)<br>
<tr><td> 40 to 60 </td><td>250 </td></tr>
❑ Asymmetric blood pressure in extremities<br>
<tr><td>20 to 40 </td><td>125 </td></tr>
❑ Shock <br>
<tr><td> <20</td><td>Contraindicated</td></tr>
❑ Pulse deficit <br>
</table></td></tr>
❑ Evolving aortic regurgitation murmur </div>}}
<tr><td>Flecainide</td><td> I A</td><td>'''Oral:''' 200 to 300 mg <br>
{{familytree | | | | | | |,|-|-|-|^|-|-|-|.| | | | | | | | }}
'''Intravenous:''' 1.5 to 3.0 mg/kg over 10 to 20 min</td></tr>
{{familytree | | | | | | C01 | | | | | | C02 | | | | | | |C01=<div style=" background: #F60A0A"> {{fontcolor|#F8F8FF|Unstable patient}} </div>|C02=Stable patient }}
<tr><td>Ibutilide</td><td>I A </td><td>1 mg over 10 min; repeat 1 mg when necessary</td></tr>
{{familytree | | | | | | |!| | | | | | | |!| | | | | | | | }}
<tr><td>Propafenone</td><td>I A</td><td>'''Oral:''' 600 mg <br>
{{familytree | | | | | | D01 | | | | | | D02 | | | | | | |D01=<div style="background: #F60A0A; text-align: left"> {{fontcolor|#F8F8FF|❑ Order urgent TTE <br> ❑ Look for the following high risk features: <br>
'''Intravenous:''' 1.5 to 2.0 mg/kg over 10 to 20 min</td></tr>
:❑ Pericardial effusion <br>
<tr><td>Amiodarone</td><td>IIa A</td><td>'''Oral:'''
:❑ Regional wall motion abnormality (RWMA) <br>
: Inpatient: 1.2 to 1.8 g per day in divided dose until 10 g total <br>  then 200 to 400 mg per day maintenance or 30 mg/kg as single dose <br>
:❑ Dilated root <br>
: Outpatient: 600 to 800 mg per day divided dose until 10 g total <br> then 200 to 400 mg per day maintenance. <br>
:❑ Aortic regurgitation (AR)}} </div> |D02=[[Aortic dissection resident survival guide#Diagnosis|Continue with diagnostic approach]] }}
'''Intravenous:'''
{{familytree | | | | | | |!| | | | | | | | | | | | | | | | }}
: 5 to 7 mg/kg over 30 to 60 min then 1.2 to 1.8 g per day continuous IV or <br>
{{familytree | | | | | | E01 | | | | | | | | | | | | | | |E01=<div style=" background: #F60A0A; text-align: left"> {{fontcolor|#F8F8FF|❑ Aortic dissection confirmed
: in divided oral doses until 10 g total then 200 to 400 mg per day maintenance.</td></tr>
❑ Transfer to Cardio-thoracic unit
</table>
❑ Perform TEE in CCU or cardiac OR }} </div>}}
{{familytree | | | | | | |!| | | | | | | | | | | | | | | | }}
{{familytree | | | | | | F01 | | | | | | | | | | | | | | |F01=<div style=" background: #F60A0A"> {{fontcolor|#F8F8FF|❑ Proceed to surgery}} </div> }}
{{familytree/end}}


===Cardioversion after 7 Days===
Look for the following: Intimal flap and tear <br> Intimal entry <br> Mobile linear flap in short axis view <br> Small central true lumen communicating with false lumen
 
<table class="wikitable">
<tr class="v-firstrow"><th>Drug</th><th>Class of Recommendation/<br> Level of Evidence</th><th> Dosage </th></tr><tr><td>Dofetilide</td><td>I A</td><td><table class="wikitable">
<tr class="v-firstrow"><th>Creatinine clearance(ml/min)</th><th>Dose (mg)</th></tr>
<tr><td> >60</td><td>500</td></tr>
<tr><td> 40 to 60 </td><td>250 </td></tr>
<tr><td>20 to 40 </td><td>125 </td></tr>
<tr><td> <20</td><td>Contraindicated</td></tr>
</table></td></tr>
<tr><td>Amiodarone</td><td>IIa A</td><td>'''Oral:'''
: Inpatient: 1.2 to 1.8 g per day in divided dose until 10 g total <br>  then 200 to 400 mg per day maintenance or 30 mg/kg as single dose <br>
: Outpatient: 600 to 800 mg per day divided dose until 10 g total <br> then 200 to 400 mg per day maintenance. <br>
'''Intravenous:'''
: 5 to 7 mg/kg over 30 to 60 min then 1.2 to 1.8 g per day continuous IV or <br>
: in divided oral doses until 10 g total then 200 to 400 mg per day maintenance.</td></tr>
<tr><td>Ibutilide</td><td>IIa A</td><td>1 mg over 10 min; repeat 1 mg when necessary</td></tr>
</table>
 
Drugs which enhance the efficacy of cardioversion when given prior to the procedure: (Level of recommendation: IIa B)
* Amiodarone
* Flecainide
* Ibutilide
* Propafenone
* Sotalol
 
===Drug Dosages for Maintenance of Sinus Rhythm===
Following table summarizes the list of most commonly used drugs and their dosages for maintenance of sinus rhythm:
<table class="wikitable">
<tr class="v-firstrow"><th>Drug</th><th>Dose</th></tr>
<tr><td>Amiodarone</td><td>100 to 400 mg</td></tr>
<tr><td>Disopyramide</td><td>400 to 750 mg </td></tr>
<tr><td>Dofetilide</td><td>5000 to 1000 mcg </td></tr>
<tr><td>Flecainide</td><td>200 to 300 mg</td></tr>
<tr><td>Procainamide</td><td>1000 to 4000 mg</td></tr>
<tr><td>Propafenone</td><td>450 to 900 mg</td></tr>
<tr><td>Quinidine</td><td>600 to 1500 mg</td></tr>
<tr><td>Sotalol</td> <td>160 to 320 mg </td></tr>
</table>
 
===Pharmacological Agents for Heart Rate Control===
<table class="wikitable">
<tr class="v-firstrow"><th>Drug</th><th>Class/LOE <br> Recommendations</th><th>Loading Dose</th><th>Maintenance Dose</th></tr>
<tr><th>Acute Setting</th></tr>
<tr><th>Heart rate control in patients without accessory pathway</th></tr>
<tr><td>Esmolol</td><td>I C</td><td>500 mcg/kg IV over 1 min</td><td>60 to 200 mcg/kg/min IV</td></tr>
<tr><td>Propanolol</td><td>I C </td><td>0.15 mg/kg IV</td><td>NA</td></tr>
<tr><td>Metoprolol</td><td>I C </td><td>2.5 to 5 mg IV bolus over 2 min; up to 3 doses</td><td>NA</td></tr>
<tr><td>Diltiazem</td><td>I B</td><td>0.25 mg/kg IV over 2 min</td><td>5 to 15 mg/h IV</td></tr>
<tr><td>Verampil</td><td>I B</td><td>0.075 to 0.15 mg/kg IV over 2 min</td><td>NA</td></tr>
<tr><th>Heart Rate Control in patients with accessory pathway</th></tr>
<tr><td>Amiodarone</td><td>IIa C</td><td>150 mg over 10 min</td><td>0.5 to 1 mg/min IV</td></tr>
<tr><th>Heart Rate Control in patients with heart failure and without accessory pathway</th></tr>
<tr><td>Digoxin</td><td>I B</td><td>0.25 mg IV each 2 h, up to 1.5 mg</td><td>0.125 to 0.375 mg daily IV or orally</td></tr>
<tr><td>Amiodarone</td><td>IIa C</td><td>150 mg over 10 min</td><td>0.5 to 1 mg/min IV</td></tr>
<tr><th>Non-Acute Setting and Chronic Maintenance Therapy</th></tr>
<tr><th>Heart rate control</th></tr>
<tr><td>Metoprolol</td><td>I C</td><td>Same as maintenance dose</td><td>25 to 100 mg twice a day, orally</td></tr>
<tr><td>Propanolol</td><td>I C</td><td>Same as maintenance dose</td><td>80 to 240 mg daily in divided doses, orally</td></tr>
<tr><td>Verampil</td><td>I B</td><td>Same as maintenance dose</td><td>120 to 360 mg daily in divided doses; slow release available, orally</td></tr>
<tr><td>Diltiazem</td><td>I B</td><td>Same as maintenance dose</td><td>120 to 360 mg daily in divided doses; slow release available, orally</td></tr>
<tr><th>Heart Rate Control in patients with heart failure and without accessory pathway</th></tr>
<tr><td>Digoxin </td><td>I C</td><td>0.5 mg by mouth daily</td><td>0.125 to 0.375 mg daily, orally</td></tr>
<tr><td>Amiodarone</td><td>IIb C</td><td>800 mg daily for 1 wk, orally <br> 600 mg daily for 1 wk, orally <br> 400 mg daily for 4 to 6 wk, orally</td><td>200 mg daily, orally</td></tr>
</table>
 
===CHADS<sub>2</sub>Scoring for Predicting Risk of Stroke===
{| class="wikitable" style = "text-align:center"
!
!Condition
!Points
|-
| &nbsp;'''C'''&nbsp;
| &nbsp;[[Congestive heart failure]]
| <center>1</center>
|-
| &nbsp;'''H'''
| &nbsp;[[Hypertension]]: blood pressure consistently above 140/90 mmHg <br> (or treated hypertension on medication)
| <center>1</center>
|-
| &nbsp;'''A'''
| &nbsp;Age >/=75 years
| <center>1</center>
|-
| &nbsp;'''D'''
| &nbsp;[[Diabetes Mellitus]]
| <center>1</center>
|-
| &nbsp;'''S<sub>2</sub>''' 
| &nbsp;Prior [[Stroke]] or [[Transient ischemic attack | TIA]] 
| <center>2</center>
|}
{{Clr}}
 
{| class="wikitable" style = "text-align:center"
|-
! Score
! Risk
! Anticoagulation Therapy
! Considerations
|-
| '''0'''
| Low
| [[Aspirin]]
| Aspirin daily
|-
| '''1'''
| Moderate
| Aspirin or Warfarin
| Aspirin daily or [[International normalized ratio|INR]] to 2.0-3.0, depending on factors such as patient preference
|-
| '''2 or greater'''
| Moderate or High
| [[Warfarin]]
| [[International normalized ratio|INR]] to 2.0-3.0, unless contraindicated (e.g. clinically significant GI bleeding, inability to obtain regular INR screening)
|}
 
Anticoagulation is recommended for 3 wk prior to and 4 wk after cardioversion for patients with AF of unknown duration or with AF for
longer than 48 h.
When acute AF produces hemodynamic instability in the form of angina pectoris, MI, shock, or pulmonary edema, immediate cardioversion should not be delayed to deliver therapeutic anticoagulation, but intravenous unfractionated heparin or subcutaneous injection of a low-molecular-weight heparin should be initiated before cardioversion by direct-current countershock or intravenous antiarrhythmic medication.
 
===Risk Factors for Stroke and Recommended Antithrombotic Therapy===
<table class="wikitable">
<tr class="v-firstrow"><th>Low Risk Factors</th><th>Moderate Risk Factors</th><th>High Risk Factors</th></tr>
<tr><td>Female gender</td><td>Age ≥ 75 years</td><td>Previous stroke, TIA or embolism </td></tr>
<tr><td>Age 65-74 years</td><td>Hypertension</td><td>Mitral stenosis</td></tr>
<tr><td>Coronary artery disease</td><td>Heart failure</td><td>Prosthetic heart valve</td></tr>
<tr><td>Thyrotoxicosis</td><td>LV ejection fraction ≤ 35%</td><td> - </td></tr>
<tr><td> - </td><td>Diabetes mellitus</td><td> - </td></tr>
</table>

Latest revision as of 22:25, 1 April 2014

First Initial Rapid Evaluation of Suspected Aortic Dissection

Shown below is an algorithm for the First Initial Rapid Evaluation (FIRE) of Aortic dissection.

 
 
 
 
 
 
 
 
 
 
 
Confirmed aortic dissection
❑ Check whether dissection occurred in ascending aorta
 
Yes
 
Consider surgical management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Start Medical management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Check Vitals
❑ Blood pressure in both arms
❑ Take the highest reading for treatment or goal therapy
❑ Is patient hemodynamically stable ?
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Control rate and pressure
❑ I.V Beta blockers or labetalol
❑ Substitute diltiazem and verapamil
If betablockers are contraindicated

❑ Goal Heart rate should be 60 beats per minute


❑ Pain control

❑ Use Opiates
 
 
 
 
 
Type A dissection

❑ Expedited surgical consultation and consider surgery (Urgent)
❑ Maintain Euvolemic status

❑ Intravenous fluid replacement
❑ Maintain mean arterial pressure (MAP) of 70 mm of hg

❑ Rule out complications using imaging study

Pericardial tamponade
Rupture of aorta
Aortic insufficiency
 
 
 
 
 
❑ Type B dissection

❑ Intravenous fluid replacement

❑ Maintain mean arterial pressure (MAP) of 70 mm of hg

❑ Start vasopressor if still hypotensive


❑ Find out etiology of hypertension

❑ Imaging to find out contained rupture
❑ Perform Transthoracic echocardiogram (TTE) to assess cardiac function

❑ Consider surgical evaluation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Can the cause of hypotension respond to surgical management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Monitor vitals closely
❑ Maintain systolic BP <120 mm of Hg
 
No
 
 
 
 
 
Yes
 
Consider surgical management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Check whether dissection involves ascending aorta
 
 
 
 
 
Yes
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Control blood pressure
❑ Intravenous vasodilator
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Monitor vitals closely
❑ Maintain systolic BP <120 mm of Hg
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Check for any complications which might require surgery
❑ Malperfusion
❑ Progressing dissection
❑ Expansion of aortic aneurysm
Uncontrolled or refractory hypertension
 
Yes
 
❑ Consider surgical management
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Switch to oral medications
Betablockers
❑ Antihypertensive regimen

❑ Follow up in the outpatient
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Identify cardinal signs and symptoms that increase the pretest probability of acute aortic rupture
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Sudden onset chest pain (tearing/ripping/sharp or stabbing)

❑ Asymmetric blood pressure in extremities
❑ Shock
❑ Pulse deficit

❑ Evolving aortic regurgitation murmur
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Unstable patient
 
 
 
 
 
Stable patient
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Order urgent TTE
❑ Look for the following high risk features:
❑ Pericardial effusion
❑ Regional wall motion abnormality (RWMA)
❑ Dilated root
❑ Aortic regurgitation (AR)
 
 
 
 
 
Continue with diagnostic approach
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Aortic dissection confirmed

❑ Transfer to Cardio-thoracic unit

❑ Perform TEE in CCU or cardiac OR
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
❑ Proceed to surgery
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Look for the following: Intimal flap and tear
Intimal entry
Mobile linear flap in short axis view
Small central true lumen communicating with false lumen