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{{Naegleria infection}}
{{CMG}}
{{CMG}}
==Overview==
Naegleria fowleri causes the disease primary amebic meningoencephalitis (PAM), a brain infection that leads to the destruction of [[brain]] tissue. In its early stages, symptoms of PAM may be similar to symptoms of [[bacterial meningitis]].


==Overview==
Initial symptoms of PAM start about 5 days (range 1 to 7 days) after infection. The initial symptoms may include [[headache]], [[fever]], [[nausea]], or [[vomiting]]. Later symptoms can include [[stiff neck]], [[confusion]], lack of attention to people and surroundings, [[loss of balance]], [[seizures]], and [[hallucinations]].
== History and Symptoms ==
Acute primary amebic meningoencephalitis (PAM) is caused by Naegleria fowleri. It presents with severe [[headache]] and other meningeal signs, [[fever]], [[vomiting]], and focal neurologic deficits, and progresses rapidly (<10 days) and frequently to [[coma]] and death. Acanthamoeba spp. causes mostly subacute or chronic granulomatous amebic encephalitis (GAE), with a clinical picture of [[headaches]], altered mental status, and focal neurologic deficit, which progresses over several weeks to death.  In addition, Acanthamoeba spp. can cause granulomatous skin lesions and, more seriously, [[keratitis]] and corneal ulcers following corneal trauma or in association with contact lens use.  Non-contact lens users and contact lens users with safe lens care practices can become infected.  However, poor contact lens hygiene and exposure to contaminated water may increase the risk among contact lens users.


==References==
==References==


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Latest revision as of 18:10, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Naegleria fowleri causes the disease primary amebic meningoencephalitis (PAM), a brain infection that leads to the destruction of brain tissue. In its early stages, symptoms of PAM may be similar to symptoms of bacterial meningitis.

Initial symptoms of PAM start about 5 days (range 1 to 7 days) after infection. The initial symptoms may include headache, fever, nausea, or vomiting. Later symptoms can include stiff neck, confusion, lack of attention to people and surroundings, loss of balance, seizures, and hallucinations.

References

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