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==Overview==
Presenting symptoms differ according to the site of the cysticerci.  [[Parenchymal]] neurocysticercosis causes all the symptoms and signs of [[Space occupying lesion|space occupying lesions]]. Extraparenchymal neurocysticercosis causes manifestations of [[increased intracranial pressure]] if cysts are present in the [[subarachnoid space]] or in the [[ventricles]], manifestations of [[spinal cord compression]] if present in the spinal cord or causes eye disease if cysts are present in the [[orbit]].
 
== History and Symptoms ==
Presenting symptoms vary according to the site of infestation:
 
===Neurocysticercosis===
 
====Parenchymal:====
 
Many cases (up to 80%) can remain [[asymptomatic]] and discovered either in [[autopsies]] or accidentally during routine imaging.<ref name="pmid2913118">{{cite journal |vauthors=Isnard RN, Pannier BM, Laurent S, London GM, Diebold B, Safar ME |title=Pulsatile diameter and elastic modulus of the aortic arch in essential hypertension: a noninvasive study |journal=J. Am. Coll. Cardiol. |volume=13 |issue=2 |pages=399–405 |year=1989 |pmid=2913118 |doi= |url=}}</ref>
 
*[[Seizures]]: Most common manifestation of [[Parenchymal|parenchymal neuroccysticercosis]].<ref name="pmid3261519">{{cite journal |vauthors=Oot RF, Melville GE, New PF, Austin-Seymour M, Munzenrider J, Pile-Spellman J, Spagnoli M, Shoukimas GM, Momose KJ, Carroll R |title=The role of MR and CT in evaluating clival chordomas and chondrosarcomas |journal=AJR Am J Roentgenol |volume=151 |issue=3 |pages=567–75 |year=1988 |pmid=3261519 |doi=10.2214/ajr.151.3.567 |url=}}</ref>Seizers can be [[Focal seizures|focal]], [[Generalized seizure|generalized]] or focal with secondary generalization.  
*[[Headache]]
*[[Nausea and vomiting]]
*Psychiatric disorders: has a wide variatoin from abnormal dysfunction and up to [[dementia]] <ref name="pmid3261519">{{cite journal |vauthors=Oot RF, Melville GE, New PF, Austin-Seymour M, Munzenrider J, Pile-Spellman J, Spagnoli M, Shoukimas GM, Momose KJ, Carroll R |title=The role of MR and CT in evaluating clival chordomas and chondrosarcomas |journal=AJR Am J Roentgenol |volume=151 |issue=3 |pages=567–75 |year=1988 |pmid=3261519 |doi=10.2214/ajr.151.3.567 |url=}}</ref>


====Extraparenchymal:====
<u>1. Ocular cysticercosis:</u>
* Symptoms depend on the exact site of infestation in the eye.


<u>2. Extraparenchymal in the brain ventricles and subarachnoid space:</u>
Cysticerci obstruct of the flow of the [[CSF]] and cause [[hydrocephalus]]. Symptoms usually result from [[increased intracranial pressure]].
*[[Headache]]
*[[Nausea and vomiting]]
*[[Decreased visual acuity]]
*[[Seizure|Seizures]]


==Overview==
<u>3. Spinal cord cysticercosis:</u>
== History and Symptoms ==
It is very rare (1.5-3% of all the cases).<ref name="pmid15926787">{{cite journal |vauthors=Alsina GA, Johnson JP, McBride DQ, Rhoten PR, Mehringer CM, Stokes JK |title=Spinal neurocysticercosis |journal=Neurosurg Focus |volume=12 |issue=6 |pages=e8 |year=2002 |pmid=15926787 |doi= |url=}}</ref>The presentaion depends on the site of the lesion.
*''Cysticerci in the muscles:'' Cysticerci in the muscles generally do not cause symptoms. However, you may be able to feel lumps under your skin.


*''Cysticerci in the eyes:'' Although rare, cysticerci may float in the eye and cause [[Blurred Vision]]. Infection in the eyes may cause Swelling or detachment of the retina.
*[[Low back pain]] that may radiate down the legs
*Weakness in the legs and feet
*[[Loss of sensation]] in the legs and feet
*Bladder and bowel [[incontinence]]
*[[Sexual dysfunction]]
*[[Foot drop]]
*Decreased or absent reflexes in the legs
*Pain in the chest and/or back
*[[Loss of sensation]] below the level of the compression
*Paralysis of respiratory muscles


*''Neurocysticercosis (cysticerci in the brain, spinal cord):'' Symptoms of neurocysticercosis depend upon where and how many cysticerci (often called lesions) are found in the brain. [[Seizures]], and [[Headache]] are the most common symptoms. However, [[confusion]], lack of attention to people and surroundings, difficulty with balance, swelling of the brain (called [[hydrocephalus]]) may also occur. Death can occur suddenly with heavy infections.
===Extraneural===


'''How long will I be infected before symptoms begin?'''
====Muscular cysticercosis====
*Can be [[asymptomatic]] and [[calcification]] discovered accidentally on imaging
*[[Muscle aches]] and weakness


Symptoms can occur months to years after infection, usually when the cysts are in the process of dying. When this happens, the brain can swell. The pressure caused by swelling is what causes most of the symptoms of neurocysticercosis. Most people with cysticerci in muscles won’t have symptoms of infection.
====Cutaneous cysticercosis====
*Can be [[asymptomatic]]
*Discomfort, pruritis and excoriations


==References==
==References==
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Latest revision as of 21:11, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Presenting symptoms differ according to the site of the cysticerci. Parenchymal neurocysticercosis causes all the symptoms and signs of space occupying lesions. Extraparenchymal neurocysticercosis causes manifestations of increased intracranial pressure if cysts are present in the subarachnoid space or in the ventricles, manifestations of spinal cord compression if present in the spinal cord or causes eye disease if cysts are present in the orbit.

History and Symptoms

Presenting symptoms vary according to the site of infestation:

Neurocysticercosis

Parenchymal:

Many cases (up to 80%) can remain asymptomatic and discovered either in autopsies or accidentally during routine imaging.[1]

Extraparenchymal:

1. Ocular cysticercosis:

  • Symptoms depend on the exact site of infestation in the eye.

2. Extraparenchymal in the brain ventricles and subarachnoid space: Cysticerci obstruct of the flow of the CSF and cause hydrocephalus. Symptoms usually result from increased intracranial pressure.

3. Spinal cord cysticercosis: It is very rare (1.5-3% of all the cases).[3]The presentaion depends on the site of the lesion.

Extraneural

Muscular cysticercosis

Cutaneous cysticercosis

References

  1. Isnard RN, Pannier BM, Laurent S, London GM, Diebold B, Safar ME (1989). "Pulsatile diameter and elastic modulus of the aortic arch in essential hypertension: a noninvasive study". J. Am. Coll. Cardiol. 13 (2): 399–405. PMID 2913118.
  2. 2.0 2.1 Oot RF, Melville GE, New PF, Austin-Seymour M, Munzenrider J, Pile-Spellman J, Spagnoli M, Shoukimas GM, Momose KJ, Carroll R (1988). "The role of MR and CT in evaluating clival chordomas and chondrosarcomas". AJR Am J Roentgenol. 151 (3): 567–75. doi:10.2214/ajr.151.3.567. PMID 3261519.
  3. Alsina GA, Johnson JP, McBride DQ, Rhoten PR, Mehringer CM, Stokes JK (2002). "Spinal neurocysticercosis". Neurosurg Focus. 12 (6): e8. PMID 15926787.


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