Primary ciliary dyskinesia MRI: Difference between revisions

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==Overview==
==Overview==


There are no [[Indication (medicine)|indications]] for [[Magnetic resonance imaging|MRI]] in Primary Ciliary Dyskinesia.
[[MRI]] scans can assess ventilation defects in patients with [[primary ciliary dyskinesia]] PCD, along with [[dextrocardia]] if present.


==MRI==
==MRI==
 
Hyperpolarized gas ventilation [[Magnetic resonance imaging|MRIs]] are performed in children to asses [[ventilation]] defects. Ventilation defects were detected in the middle and lower lobes, but there were often additional ventilation defects present in the upper lobes, possibly caused by [[mucus]] plugging that precedes structural change these images are suggestive of PCD in children. [[Ventilation|Ventilation MRI]] is more sensitive than [[CT-scans|CT]] in assessing for [[ventilation]] abnormalities.<ref>Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, et al. Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax 2017;72:760–762.</ref>
 
[[MRI_gif.pdf|200px|thumb|left|alt text]]
[[MRI_gif.pdf|200px|thumb|left|alt text]]



Latest revision as of 15:40, 20 September 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hafsa Ghaffar, M.B.B.S[2]

Overview

MRI scans can assess ventilation defects in patients with primary ciliary dyskinesia PCD, along with dextrocardia if present.

MRI

Hyperpolarized gas ventilation MRIs are performed in children to asses ventilation defects. Ventilation defects were detected in the middle and lower lobes, but there were often additional ventilation defects present in the upper lobes, possibly caused by mucus plugging that precedes structural change these images are suggestive of PCD in children. Ventilation MRI is more sensitive than CT in assessing for ventilation abnormalities.[1] 200px|thumb|left|alt text

References

  1. Marshall H, Horsley A, Taylor CJ, Smith L, Hughes D, Horn FC, et al. Detection of early subclinical lung disease in children with cystic fibrosis by lung ventilation imaging with hyperpolarised gas MRI. Thorax 2017;72:760–762.

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