Follicular thyroid cancer diagnostic study of choice: Difference between revisions

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*[[Biopsy]] is the [[Gold standard (test)|gold standard]] for [[Diagnosis|diagnosing]] thyroid cancer.<ref>{{Cite web|url=https://www.cancer.org/cancer/thyroid-cancer/detection-diagnosis-staging/how-diagnosed.html|title=|last=|first=|date=|website=|archive-url=|archive-date=|dead-url=|access-date=}}</ref>
*[[Biopsy]] is the [[Gold standard (test)|gold standard]] for [[Diagnosis|diagnosing]] thyroid cancer.<ref>{{Cite web|url=https://www.cancer.org/cancer/thyroid-cancer/detection-diagnosis-staging/how-diagnosed.html|title=|last=|first=|date=|website=|archive-url=|archive-date=|dead-url=|access-date=}}</ref>
*[[Biopsy]] can be taken by the following methods:
*[[Biopsy]] can be taken by the following methods:
====1. Fine Needle Aspiration Biopsy (FNAC)====
**'''Fine Needle Aspiration Biopsy (FNAC)'''
* It involves [[extraction]] of [[thyroid]] [[Tissue (biology)|tissue]] using a thin needle.  
*** It involves [[extraction]] of [[thyroid]] [[Tissue (biology)|tissue]] using a thin needle.
*The needle is inserted through the [[skin]] into the [[thyroid]]. Several [[Tissue (biology)|tissue]] samples are taken from different parts of the [[thyroid]].
***The needle is inserted through the [[skin]] into the [[thyroid]]. Several [[Tissue (biology)|tissue]] samples are taken from different parts of the [[thyroid]].
 
**'''Surgical Biopsy'''
====2. Surgical Biopsy====
***Surgical [[biopsy]] is the removal of the [[thyroid]] nodule or one [[lobe]] of the [[thyroid]] during [[surgery]].
* Surgical [[biopsy]] is the removal of the [[thyroid]] nodule or one [[lobe]] of the [[thyroid]] during [[surgery]].
*** On microscopic examination, trabecular follicular tumor cells that invade [[tumor]] capsule or surrounding vascular structures, are found.
* On microscopic examination, trabecular follicular tumor cells that invade [[tumor]] capsule or surrounding vascular structures, are found.


====Images of Biopsy Specimen====
====Images of Biopsy Specimen====
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! style="background: #F5F5F5;" |M1
! style="background: #F5F5F5;" |M1
|}
|}
==Reference==
==Reference==
{{Reflist|2}}
{{Reflist|2}}

Latest revision as of 15:42, 29 October 2019

Follicular thyroid cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Follicular thyroid cancer from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

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Laboratory Findings

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CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Biopsy is the gold standard for diagnosing thyroid cancer. According to the American Joint Committee on Cancer (AJCC), there are 4 stages of follicular thyroid cancer based on the clinical features and findings on imaging. Each stage is assigned a letter and a number that designate the tumor size, number of lymph node regions involved, and metastasis.

Diagnostic Study of Choice

Study of Choice

Images of Biopsy Specimen

Staging[4]


Primary tumor
Tumor size Sub-stage Finding Image
T0
  • No evidence of primary tumor
T1
T1 a
T1 b
  • Tumor >1 cm but ≤2 cm in greatest dimension, limited to the thyroid
T2
  • Tumor >2 cm but ≤4 cm in greatest dimension, limited to the thyroid
T3
  • Tumor >4 cm limited to the thyroid, or gross extrathyroidal extension invading only strap muscles
T3 a
T3 b
T4
  • Tumor includes gross extrathyroidal extension beyond the strap muscles
T4 a
T4 b
TX
  • Primary tumor cannot be assessed
Regional lymph node involvement
Node involvement Sub-stage Finding Image
N0
N0 a
N0 b
N1
N1 a
N1 b
NX
Distant metastasis
Presence of metastasis Sub-stage Finding Image
M0
M1 IV


Anatomic Stage/Prognostic Groups
Stage T N M
Follicular thyroid carcinoma
YOUNGER THAN 55 YEARS
I Any T Any N M0
II Any T Any N M1
55 YEARS AND OLDER
I T1 Any N M0
II T1 N1 M0
T2 N1 M0
T3a Any N M0
T3b Any N M0
III T4a Any N M0
IVA T4b Any N M0
IVB Any T Any N M1
T1 N1 M0
T2 N1 M0
T3a N1 M0
T3b Any N M0
T4 Any N M0
IVC Any T Any N M1

Reference

  1. https://www.cancer.org/cancer/thyroid-cancer/detection-diagnosis-staging/how-diagnosed.html. Missing or empty |title= (help)
  2. http://librepathology.org/wiki/index.php/File:Metastatic_follicular_thyroid_carcinoma_-_Case_264_(8558730243).jpg Accessed on October, 29 2015
  3. http://librepathology.org/wiki/index.php/File:Metastatic_follicular_thyroid_carcinoma_-_Case_264_(8559837390).jpg Accessed on October, 29 2015
  4. "Thyroid Cancer Treatment (Adult) (PDQ®)–Health Professional Version - National Cancer Institute".