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__NOTOC__
{{Gangrene(patient information)}}
{{Gangrene(patient information}}
'''For the WikiDoc page for this topic, click [[Gangrene|here]]'''
'''For the WikiDoc page for this topic, click [[Gangrene|here]]'''


'''Editor-In-Chief:'''{{CMG}}; '''Associate Editor(s)-In-Chief:''' {{SM}};  
{{CMG}}; '''Associate Editor-In-Chief:''' {{SM}}; [[User:Edzelco|Edzel Lorraine Co, D.M.D., M.D.]]


==Overview==
==Overview==
Gangrene is the death of tissue in part of the body.
==What are the symptoms of Gangrene?==
The symptoms depend on the location and cause of the gangrene. If the skin is involved, or the gangrene is close to the skin, the symptoms may include:


* Discoloration (blue or black if skin is affected; red or bronze if the affected area is beneath the skin)
*[[Gangrene]] is the [[death]] of [[tissue]] in part of the [[body]] due to lack of [[blood supply]].
*It is an alarming and [[life-threatening]] condition.
*There are various types of [[gangrene]].
**[[Dry gangrene|'''Dry gangrene''']] - The [[tissue]] gets dry and falls off. This is commonly observed on the [[fingers]] and [[toes]].
**[[Wet gangrene|'''Wet gangrene''']] - The [[tissue]] looks swollen and with some [[blisters]].
**[[Gas gangrene|'''Gas gangrene''']] - The [[tissue]] gets infected with [[bacteria]] causing build-up of gas bubbles within it.


* Foul-smelling discharge
==What are the symptoms of gangrene?==


* Loss of feeling in the area (which may happen after severe pain in the area)
*[[Symptoms]] differ according to the type of [[gangrene]] present. Table 1 summarizes the [[symptoms]] observed in each type of [[gangrene]].


If the affected area is inside the body (such as gangrene of the gallbladder or gas gangrene), the symptoms may include:


* Confusion
{| border="2"
|+'''Table 1. [[Symptoms]] of [[Gangrene]].''' 


* Fever
!Type!!Symptoms
|-
|[[Dry Gangrene]]||Dry and hard [[skin]] and [[tissue]].
|-
|[[Wet Gangrene]]||[[Tissue]] that appears wet, [[swelling]], darkening of the [[skin]], [[blisters]], and putrid smell.
|-
|[[Gas Gangrene]]||[[Numbness]] or heavy feeling in the affected area, [[confusion]], intense [[pain]], [[body]] [[malaise]], [[fever]], [[skin color changes]] to red, brown, or purple, [[blisters]], and a crackling sound is heard from [[tissues]] when pressing it.
|}


* Gas in tissues beneath the skin
==What causes gangrene?==
*[[Wound]] [[constriction]] that is followed by [[hemorrhage]].
*[[Body]] part [[compression]].
*[[Necrosis]] due to [[bandages]].


* General ill feeling
* Low blood pressure
* Persistent or severe pain
==What causes Gangrene?==
Gangrene happens when a body part loses its blood supply. This may happen from injury, an infection, or other causes.
==Who is at highest risk?==
* You have a higher risk for gangrene if you have:
* A serious injury
* Blood vessel disease (such as arteriosclerosis, also called hardening of the arteries, in your arms or legs)
* Diabetes
* Suppressed immune system (for example, from HIV or chemotherapy)
* Surgery
==Diagnosis==
==Diagnosis==


* The doctor may diagnose gangrene from a physical examination. In addition, the following tests and procedures may be used to diagnose gangrene:
*The type of test needed is based on the type of [[gangrene]] the patient has.
 
*[[Diagnostic tests]] that are usually done include:
* Arteriogram (special x-ray to see any blockages in the blood vessels) to help plan treatment for blood vessel disease
**[[Imaging tests|'''Imaging tests''']] such as [[computed tomography scan]] ([[CT scan]]), and [[magnetic resonance imaging]] ([[MRI]]) to look for [[signs]] of [[gas]] inside the [[body]].
 
**[[Blood tests|'''Blood tests''']] to look for [[signs]] of [[infection]].
* Blood tests (white blood cell [WBC] count may be high)
**[[Blood flow tests|'''Blood flow tests''']] to detect the source of problems in the [[blood vessels]] and identify its [[severity]].
 
* CT scan to examine internal organs
 
* Culture of the tissue or fluid from wounds to identify bacterial infection
 
* Examining tissue under the microscope to look for cell death
 
* Surgery to find and remove dead tissue
 
* X-rays


==When to seek urgent medical care?==
==When to seek urgent medical care?==
Call your doctor immediately if:
* A wound does not heal or there are frequent sores in an area


* An area of your skin turns blue or black
*If [[numbness]] is felt on the [[fingers]] or [[toes]], a visit to the [[doctor]] should be done right away.
*Non-[[healing]] [[wounds]] or any [[skin changes]] on the [[foot]] in a [[patient]] with [[diabetes]] should be evaluated as soon as possible.
*After [[surgery]], if the [[patient]] experiences worsening [[pain]] or [[skin]] color changes on the affected area, or if the patient starts to feel [[sick]], an urgent visit to the [[doctor]] is needed.


* There is foul-smelling discharge from any wound on your body
* You have persistent, unexplained pain in an area
* You have persistent, unexplained fever
==Treatment options==
==Treatment options==
Gangrene requires urgent evaluation and treatment. In general, dead tissue should be removed to allow healing of the surrounding living tissue and prevent further infection. Depending on the area that has the gangrene, the person's overall condition, and the cause of the gangrene, treatment may include:


* Amputating the body part that has gangrene
*Cutting away of [[dying]] or [[dead]] [[tissues]] to prevent spreading of [[gangrene]].
*[[Amputation]] - A type of [[surgery]] wherein removal of the [[body parts]] affected with [[gangrene]] is done.
*[[Intravenous]] [[antibiotic]] [[medications]]


* An emergency operation to find and remove dead tissue
==Where to find medical care for gangrene?==
 
* An operation to improve blood supply to the area
 
* Antibiotics
 
* Repeated operations to remove dead tissue (debridement)
 
* Treatment in the intensive care unit (for severely ill patients)
==Where to find medical care for Gangrene?==
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Condition}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Gangrene]
[http://maps.google.com/maps?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|map+top+hospital+Condition}}}}&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&ie=UTF-8&sa=N&hl=en&tab=wl Directions to Hospitals Treating Gangrene]


==Prevention==
==Prevention==
Gangrene may be prevented if it is treated before the tissue damage is irreversible. Wounds should be treated properly and watched carefully for signs of infection (such as spreading redness, swelling, or drainage) or failure to heal.


People with diabetes or blood vessel disease should routinely examine their feet for any signs of injury, infection, or change in skin color and seek care as needed.
*Maintain a normal [[blood sugar level]].
*Have a good habit of checking the [[feet]] regularly.
*Avoid using contaminated [[heroin]] or any chemicals that are injected into the [[body]].
 
==What to expect (Outlook/Prognosis)?==
==What to expect (Outlook/Prognosis)?==
What to expect depends on where the gangrene is in the body, how much gangrene there is, and the person's overall condition. If treatment is delayed, the gangrene is extensive, or the person has other significant medical problems, they may die.
 
*The [[prognosis]] will depend on the [[severity]] of the [[gangrene]].
*In some cases, [[survival]] is still noted even if a certain [[body part]] has fallen off.


==Possible complications==
==Possible complications==
Complications depend on where in the body the gangrene is, how much gangrene there is, the cause of the gangrene, and the person's overall condition. Complications can include:
*[[Amputation]] and [[death]] are the most common [[complication]] of [[gangrene]]. <ref name="pmid25439329">{{cite journal| author=Elsayed S, Clavijo LC| title=Critical limb ischemia. | journal=Cardiol Clin | year= 2015 | volume= 33 | issue= 1 | pages= 37-47 | pmid=25439329 | doi=10.1016/j.ccl.2014.09.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25439329  }} </ref>


Disability from amputation or removal of dead tissue
Prolonged wound healing or the need for reconstructive surgery, such as skin grafting
==Sources==
==Sources==


http://www.nlm.nih.gov/medlineplus/ency/article/007218.htm
http://www.nlm.nih.gov/medlineplus/ency/article/007218.htm
[[Category:Signs and symptoms]]
 
[[Category:Surgery]]
[[Category:Surgery]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
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<references />

Latest revision as of 22:53, 9 April 2022

Gangrene

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for Gangrene?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

Gangrene On the Web

Ongoing Trials at Clinical Trials.gov

Images of Gangrene

Videos on Gangrene

FDA on Gangrene

CDC on Gangrene

Gangrene in the news

Blogs on Gangrene

Directions to Hospitals Treating Gangrene

Risk calculators and risk factors for Gangrene

For the WikiDoc page for this topic, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Shivali Marketkar, M.B.B.S. [2]; Edzel Lorraine Co, D.M.D., M.D.

Overview

What are the symptoms of gangrene?


Table 1. Symptoms of Gangrene.
Type Symptoms
Dry Gangrene Dry and hard skin and tissue.
Wet Gangrene Tissue that appears wet, swelling, darkening of the skin, blisters, and putrid smell.
Gas Gangrene Numbness or heavy feeling in the affected area, confusion, intense pain, body malaise, fever, skin color changes to red, brown, or purple, blisters, and a crackling sound is heard from tissues when pressing it.

What causes gangrene?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for gangrene?

Directions to Hospitals Treating Gangrene

Prevention

  • Maintain a normal blood sugar level.
  • Have a good habit of checking the feet regularly.
  • Avoid using contaminated heroin or any chemicals that are injected into the body.

What to expect (Outlook/Prognosis)?

Possible complications

Sources

http://www.nlm.nih.gov/medlineplus/ency/article/007218.htm

Template:WH Template:WS

  1. Elsayed S, Clavijo LC (2015). "Critical limb ischemia". Cardiol Clin. 33 (1): 37–47. doi:10.1016/j.ccl.2014.09.008. PMID 25439329.