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'''Editor-In-Chief:''' [[User:C Michael Gibson|C. Michael Gibson, M.S., M.D.]] [Mailto:charlesmichaelgibson@gmail.com| <nowiki>[1]</nowiki>]; '''Associate Editor(s)-in-Chief:''' [[User:AroojNaz|Arooj Naz, M.B.B.S]]<br />
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{{Bacterial pneumonia}}
{{Bacterial pneumonia}}
Pneumonia is a disease that has been prevalent for centuries and is a condition that many physicians can claim to have seen and treated in healthcare environments. In fact, a majority of deaths during the Influenza Pandemic of 1918 were attributed to a fatal bacterial pneumonia following the initial viral infection.<ref name="pmid18710327">{{cite journal| author=Morens DM, Taubenberger JK, Fauci AS| title=Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. | journal=J Infect Dis | year= 2008 | volume= 198 | issue= 7 | pages= 962-70 | pmid=18710327 | doi=10.1086/591708 | pmc=2599911 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18710327  }} </ref>
==Overview==
One of the earliest confirmed cases of bacterial pneumonia can be traced back to 1880, when Louis Pasteur and George Sternberg first isolated the most common microorganism responsible, ''Streptococcus pneumoniae''. Due to its high mortality rate, pneumonia was often referred to as “captain of the men of death” in the 20th century.<ref name="pmid24293314">{{cite journal| author=Gennaris A, Collet JF| title=The 'captain of the men of death', Streptococcus pneumoniae, fights oxidative stress outside the 'city wall'. | journal=EMBO Mol Med | year= 2013 | volume= 5 | issue= 12 | pages= 1798-800 | pmid=24293314 | doi=10.1002/emmm.201303482 | pmc=3914527 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24293314  }} </ref>
Since the 20th century, [[bacterial pneumonia]] has been identified as a formidable infectious disease and was largely held responsible for deaths during the Influenza Pandemic of 1918. It was often referred to as “captain of the men of death” during this timeframe. The most common causative bacterial strain, ''[[Streptococcus pneumoniae]]'', was first isolated in 1880 by Louis Pasteur and [[George Sternberg]]. In general, the disease has varying outcomes. The discovery of modern-day antibiotics have entirely changed how treatment is approached but, before then, [[blood letting]] was a common method of treatment as was described by William Osler in his textbook, ''The Principles and Practice of Medicine'', written in 1892.
Before the discovery of present-day formidable antibiotics, a common method of treating the disease included bloodletting or the use of leeches, as described by William Osler in his textbook, ''The Principles and Practice of Medicine'', written in 1892.<ref name="pmid31384189">{{cite journal| author=Bryan CS| title=New observations support William Osler's rationale for systemic bloodletting. | journal=Proc (Bayl Univ Med Cent) | year= 2019 | volume= 32 | issue= 3 | pages= 372-376 | pmid=31384189 | doi=10.1080/08998280.2019.1615331 | pmc=6650279 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31384189  }} </ref>


==Historical Perspective==
[[Pneumonia]] is a disease that has been prevalent for centuries and is a condition that many physicians can claim to have seen and treated in healthcare environments. 
One of the earliest confirmed cases of [[bacterial pneumonia]] can be traced back to 1880, when Louis Pasteur and George Sternberg first isolated the most common microorganism responsible, ''[[Streptococcus pneumoniae]]''. Due to its high mortality rate, pneumonia was often referred to as “captain of the men of death” in the 20th century.<ref name="pmid24293314">{{cite journal| author=Gennaris A, Collet JF| title=The 'captain of the men of death', Streptococcus pneumoniae, fights oxidative stress outside the 'city wall'. | journal=EMBO Mol Med | year= 2013 | volume= 5 | issue= 12 | pages= 1798-800 | pmid=24293314 | doi=10.1002/emmm.201303482 | pmc=3914527 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24293314  }} </ref> In fact, a majority of deaths during the [[Influenza]] [[Pandemic]] of 1918 were attributed to a fatal bacterial pneumonia following the initial [[viral infection]].<ref name="pmid18710327">{{cite journal| author=Morens DM, Taubenberger JK, Fauci AS| title=Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. | journal=J Infect Dis | year= 2008 | volume= 198 | issue= 7 | pages= 962-70 | pmid=18710327 | doi=10.1086/591708 | pmc=2599911 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18710327  }} </ref>
Before the discovery of present-day formidable [[antibiotics]], a common method of treating the disease included [[bloodletting]] or the use of leeches, as described by William Osler in his textbook, ''The Principles and Practice of Medicine'', written in 1892.<ref name="pmid31384189">{{cite journal| author=Bryan CS| title=New observations support William Osler's rationale for systemic bloodletting. | journal=Proc (Bayl Univ Med Cent) | year= 2019 | volume= 32 | issue= 3 | pages= 372-376 | pmid=31384189 | doi=10.1080/08998280.2019.1615331 | pmc=6650279 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31384189  }} </ref> Affected patients would be drained of their blood in hopes of ridding the body of [[toxins]] and [[illnesses]]. With the discovery of modern medicine, such practices have become sparse with the exception of a few diseases.


==References==
==References==
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[[Category:Pneumonia|Pneumonia]]
[[Category:Pneumonia|Pneumonia]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:Up to Date]]


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Latest revision as of 00:09, 19 March 2022

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arooj Naz, M.B.B.S

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Overview

Since the 20th century, bacterial pneumonia has been identified as a formidable infectious disease and was largely held responsible for deaths during the Influenza Pandemic of 1918. It was often referred to as “captain of the men of death” during this timeframe. The most common causative bacterial strain, Streptococcus pneumoniae, was first isolated in 1880 by Louis Pasteur and George Sternberg. In general, the disease has varying outcomes. The discovery of modern-day antibiotics have entirely changed how treatment is approached but, before then, blood letting was a common method of treatment as was described by William Osler in his textbook, The Principles and Practice of Medicine, written in 1892.

Historical Perspective

Pneumonia is a disease that has been prevalent for centuries and is a condition that many physicians can claim to have seen and treated in healthcare environments.

One of the earliest confirmed cases of bacterial pneumonia can be traced back to 1880, when Louis Pasteur and George Sternberg first isolated the most common microorganism responsible, Streptococcus pneumoniae. Due to its high mortality rate, pneumonia was often referred to as “captain of the men of death” in the 20th century.[1] In fact, a majority of deaths during the Influenza Pandemic of 1918 were attributed to a fatal bacterial pneumonia following the initial viral infection.[2]

Before the discovery of present-day formidable antibiotics, a common method of treating the disease included bloodletting or the use of leeches, as described by William Osler in his textbook, The Principles and Practice of Medicine, written in 1892.[3] Affected patients would be drained of their blood in hopes of ridding the body of toxins and illnesses. With the discovery of modern medicine, such practices have become sparse with the exception of a few diseases.

References

  1. Gennaris A, Collet JF (2013). "The 'captain of the men of death', Streptococcus pneumoniae, fights oxidative stress outside the 'city wall'". EMBO Mol Med. 5 (12): 1798–800. doi:10.1002/emmm.201303482. PMC 3914527. PMID 24293314.
  2. Morens DM, Taubenberger JK, Fauci AS (2008). "Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness". J Infect Dis. 198 (7): 962–70. doi:10.1086/591708. PMC 2599911. PMID 18710327.
  3. Bryan CS (2019). "New observations support William Osler's rationale for systemic bloodletting". Proc (Bayl Univ Med Cent). 32 (3): 372–376. doi:10.1080/08998280.2019.1615331. PMC 6650279 Check |pmc= value (help). PMID 31384189.

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