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{{Ovarian germ cell tumor}}
{{Ovarian germ cell tumor}}
{{CMG}}{{AE}} {{Sahar}} {{MD}}
==Overview==
It is difficult to distinguish [[ovarian]] [[germ cell]] [[tumors]] on [[ultrasound]] alone. Both [[solid]] and [[cystic]] [[lesions]] with [[calcification]] may be present. Dysgerminoma often appears as a [[Echogenicity|hypoechoic]] [[mass]] while other [[ovarian]] [[germ cell]] [[tumors]] often have variable [[echogenicity]]. Ovarian teratoma may be further characterized by the presence of [[sebaceous]] and [[hair]] components arising from the Rokitansky protuberance.
==Ultrasound==
'''Ovarian mature teratoma'''
*[[Ultrasound]] is the most frequently used [[modality]] for the [[diagnosis]].<ref name="SabaGuerriero2009">{{cite journal|last1=Saba|first1=Luca|last2=Guerriero|first2=Stefano|last3=Sulcis|first3=Rosa|last4=Virgilio|first4=Bruna|last5=Melis|first5=GianBenedetto|last6=Mallarini|first6=Giorgio|title=Mature and immature ovarian teratomas: CT, US and MR imaging characteristics|journal=European Journal of Radiology|volume=72|issue=3|year=2009|pages=454–463|issn=0720048X|doi=10.1016/j.ejrad.2008.07.044}}</ref>
*On [[Ultrasound]] imaging, it may have [[Variable-order Markov model|variable]] appearances, however, the three most common appearances from the most common to least common include:<ref name="SabaGuerriero2009">{{cite journal|last1=Saba|first1=Luca|last2=Guerriero|first2=Stefano|last3=Sulcis|first3=Rosa|last4=Virgilio|first4=Bruna|last5=Melis|first5=GianBenedetto|last6=Mallarini|first6=Giorgio|title=Mature and immature ovarian teratomas: CT, US and MR imaging characteristics|journal=European Journal of Radiology|volume=72|issue=3|year=2009|pages=454–463|issn=0720048X|doi=10.1016/j.ejrad.2008.07.044}}</ref><ref name="pmid11259710">{{cite journal |vauthors=Outwater EK, Siegelman ES, Hunt JL |title=Ovarian teratomas: tumor types and imaging characteristics |journal=Radiographics |volume=21 |issue=2 |pages=475–90 |date=2001 |pmid=11259710 |doi=10.1148/radiographics.21.2.g01mr09475 |url=}}</ref>
**[[Cystic]] [[lesion]] with a projecting [[Tubercle (anatomy)|tubercle]] (Rokitansky [[nodule]]) into the [[cyst]] [[lumen]] that is [[Dens|densely]] [[echogenic]]
**A mass with partial or diffuse echogenicity due to  [[sebaceous]] material and [[ hair]] within the [[cyst]] [[cavity]]
**A [[cyst]] [[cavity]] with multiple thin, [[echogenic]] [[bands]] owing to [[hair]] materials
'''Immature ovarian teratoma'''
* [[Ultrasound imaging]] is not helpful for the [[diagnosis]] of immature teratoma.<ref name="OutwaterSiegelman2001">{{cite journal|last1=Outwater|first1=Eric K.|last2=Siegelman|first2=Evan S.|last3=Hunt|first3=Jennifer L.|title=Ovarian Teratomas: Tumor Types and Imaging Characteristics|journal=RadioGraphics|volume=21|issue=2|year=2001|pages=475–490|issn=0271-5333|doi=10.1148/radiographics.21.2.g01mr09475}}</ref>
* The [[Ultrasound|US]] finding are usually nonspecific and include:
** [[Heterogeneous]] appearance with partially [[solid]] [[lesion]]
** Foci of [[calcification]]
'''Monodermal teratoma'''
* Struma ovarii:
** Nonspecific finding on the [[ultrasound imaging]].<ref name="OutwaterSiegelman2001">{{cite journal|last1=Outwater|first1=Eric K.|last2=Siegelman|first2=Evan S.|last3=Hunt|first3=Jennifer L.|title=Ovarian Teratomas: Tumor Types and Imaging Characteristics|journal=RadioGraphics|volume=21|issue=2|year=2001|pages=475–490|issn=0271-5333|doi=10.1148/radiographics.21.2.g01mr09475}}</ref>
** A [[heterogeneous]] [[mass]] which is predominantly [[solid]]
** A complex [[mass]] with multiple [[solid]] and [[cystic]] areas
'''Dysgerminoma'''
* They are purely [[solid]] (with rare exceptions)<ref name="ShaabanRezvani2014">{{cite journal|last1=Shaaban|first1=Akram M.|last2=Rezvani|first2=Maryam|last3=Elsayes|first3=Khaled M.|last4=Baskin|first4=Henry|last5=Mourad|first5=Amr|last6=Foster|first6=Bryan R.|last7=Jarboe|first7=Elke A.|last8=Menias|first8=Christine O.|title=Ovarian Malignant Germ Cell Tumors: Cellular Classification and Clinical and Imaging Features|journal=RadioGraphics|volume=34|issue=3|year=2014|pages=777–801|issn=0271-5333|doi=10.1148/rg.343130067}}</ref>
* [[Lobular|Lobulated]] components with [[heterogeneous]] [[echogenicity]] and with well-defined borders.
On color and power [[Doppler ultrasound]]:
* These [[Tumor|tumors]] are highly [[Vascular|vascularized]].
'''Yolk sac tumor'''
* [[Heterogeneous]] [[echogenicity]] in the [[solid]] portion<ref name="ShaabanRezvani2014">{{cite journal|last1=Shaaban|first1=Akram M.|last2=Rezvani|first2=Maryam|last3=Elsayes|first3=Khaled M.|last4=Baskin|first4=Henry|last5=Mourad|first5=Amr|last6=Foster|first6=Bryan R.|last7=Jarboe|first7=Elke A.|last8=Menias|first8=Christine O.|title=Ovarian Malignant Germ Cell Tumors: Cellular Classification and Clinical and Imaging Features|journal=RadioGraphics|volume=34|issue=3|year=2014|pages=777–801|issn=0271-5333|doi=10.1148/rg.343130067}}</ref>
* [[Septa|Septas]] dividing the [[cystic]] portion
'''Embryonal carcinoma'''
* There is no specific [[imaging]] criteria for embryonal carcinoma.


{{CMG}}{{AE}} {{MD}}
==References==
{{reflist|2}}
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Gynecology]]
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Latest revision as of 13:56, 22 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Monalisa Dmello, M.B,B.S., M.D. [3]

Overview

It is difficult to distinguish ovarian germ cell tumors on ultrasound alone. Both solid and cystic lesions with calcification may be present. Dysgerminoma often appears as a hypoechoic mass while other ovarian germ cell tumors often have variable echogenicity. Ovarian teratoma may be further characterized by the presence of sebaceous and hair components arising from the Rokitansky protuberance.

Ultrasound

Ovarian mature teratoma

Immature ovarian teratoma

Monodermal teratoma

Dysgerminoma

On color and power Doppler ultrasound:

Yolk sac tumor

Embryonal carcinoma

  • There is no specific imaging criteria for embryonal carcinoma.

References

  1. 1.0 1.1 Saba, Luca; Guerriero, Stefano; Sulcis, Rosa; Virgilio, Bruna; Melis, GianBenedetto; Mallarini, Giorgio (2009). "Mature and immature ovarian teratomas: CT, US and MR imaging characteristics". European Journal of Radiology. 72 (3): 454–463. doi:10.1016/j.ejrad.2008.07.044. ISSN 0720-048X.
  2. Outwater EK, Siegelman ES, Hunt JL (2001). "Ovarian teratomas: tumor types and imaging characteristics". Radiographics. 21 (2): 475–90. doi:10.1148/radiographics.21.2.g01mr09475. PMID 11259710.
  3. 3.0 3.1 Outwater, Eric K.; Siegelman, Evan S.; Hunt, Jennifer L. (2001). "Ovarian Teratomas: Tumor Types and Imaging Characteristics". RadioGraphics. 21 (2): 475–490. doi:10.1148/radiographics.21.2.g01mr09475. ISSN 0271-5333.
  4. 4.0 4.1 Shaaban, Akram M.; Rezvani, Maryam; Elsayes, Khaled M.; Baskin, Henry; Mourad, Amr; Foster, Bryan R.; Jarboe, Elke A.; Menias, Christine O. (2014). "Ovarian Malignant Germ Cell Tumors: Cellular Classification and Clinical and Imaging Features". RadioGraphics. 34 (3): 777–801. doi:10.1148/rg.343130067. ISSN 0271-5333.

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