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| {{Infobox_Disease |
| | #REDIRECT[[Gallbladder cancer]] |
| Name = {{PAGENAME}} |
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| Image = |
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| Caption = |
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| DiseasesDB = |
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| ICD10 = C23–C24 |
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| ICD9 = {{ICD9|156}} |
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| ICDO = |
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| OMIM = |
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| MedlinePlus = |
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| eMedicineSubj = |
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| }}
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| {{Gallbladder adenocarcinoma}}
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| {{CMG}}
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| ==[[Gallbladder adenocarcinoma overview|Overview]]==
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| ==Demographics==
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| Gallbladder adenocarcinoma predominantly affects older persons with long-standing [[cholecystolithiasis]].
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| ==Risk Factors==
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| * Age
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| * Gallstones and gallbladder inflammation
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| * Family history
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| * Porcelain gallbladder
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| * Cigarette smoking and other chemicals
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| * Abnormalities of the pancreas and bile duct
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| * Gallbladder polyps
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| * Obesity
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| * Diet
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| * Race
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| * Typhoid
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| * Hormone replacement therapy
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| ==Diagnosis==
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| <gallery>
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| Image:Gallbladder-adenocarcinoma-001.jpg|CT: Gallbladder adenocarcinoma
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| Image:Gallbladder-adenocarcinoma-002.jpg|CT: Gallbladder adenocarcinoma
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| Image:Gallbladder-adenocarcinoma-003.jpg|CT: Gallbladder adenocarcinoma
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| Image:Gallbladder-adenocarcinoma-004.jpg|CT: Gallbladder adenocarcinoma
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| Image:Gallbladder-adenocarcinoma-005.jpg|CT: Gallbladder adenocarcinoma
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| </gallery>
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| ===Case Example===
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| <gallery>
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| Image:Gallbladder adenocarcinoma 001.jpg|69 year old women with two month history of right upper quadrant pain . Large heterogenous, hypovascular liver mass which abuts an abnormal - appearing gallbladder
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| Image:Gallbladder adenocarcinoma 002.jpg|Diagnostic considerations here would include, first, a locally invasive gallbladder adenocarcinoma and second, an occult colon carcinoma.
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| Image:Gallbladder adenocarcinoma 003.jpg|Cholangiocarcinoma is considered less likely due to the lack of biliary obstruction.
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| Image:Gallbladder adenocarcinoma 004.jpg|Adenopathies
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| Image:Gallbladder adenocarcinoma 005.jpg|3.5 cm simple cyst associated with the upper pole of the right kidney.
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| </gallery>
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| ==Differential Diagnosis==
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| ===Squamous cell gallbladder cancer===
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| Squamous cell cancers develop from the skin-like cells that form the lining of the gallbladder, along with the gland cells. Doctors treat these cancers in the same way as adenocarcinomas.
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| ===Adenosquamous gallbladder cancer===
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| Adenosquamous carcinomas are cancers that have both squamous cancer cells and glandular cancer cells. Your doctor may call this a 'mixed histology'. Doctors treat these cancers in the same way as adenocarcinomas.
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| ===Small cell cancer of the gallbladder===
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| Small cell carcinomas are also called oat cell carcinomas. They are called this because the cancer cells are a distinctive oat shape.
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| ===Gallbladder sarcomas===
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| Sarcoma is the name for a cancer that affects the supportive or protecting tissues of the body – also called the connective tissues. Muscles, blood vessels and nerves are all connective tissues. A cancer that begins in the muscle layer of the gallbladder is a sarcoma.
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| ==Histopathological Findings==
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| <gallery>
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| Image:Gallbladder adenocarcinoma (2) histopathology.jpg|Gallbladder adenocarcinoma histopathology
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| Image:Gallbladder adenocarcinoma (3) lymphatic invasion histopathology.jpg|Gallbladder adenocarcinoma: Lymphatic invasion histopathology
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| </gallery>
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| ==See Also==
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| *[[Cholangiocarcinoma]]
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| *[[Gallbladder wall thickening]]
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| *[[Gallbladder cancer]]
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| ==Additional Resources==
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| * [http://www.cancer.gov/cancerinfo/types/gallbladder/ Gallbladder cancer at National Cancer Institute of USA]
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| {{Digestive system neoplasia}}
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| {{Symptoms and signs}}
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| {{SIB}}
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| [[Category:Oncology]]
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| [[Category:Gastroenterology]]
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