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| __NOTOC__ | | __NOTOC__ |
| | {{Tick-borne encephalitis}} |
| {{CMG}} {{AE}} {{IMD}} | | {{CMG}} {{AE}} {{IMD}} |
| {{Tick-borne encephalitis}}
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| ==Overview== | | ==Overview== |
| Treatments for tick-borne encephalitis may be categorized according to a mainstay, phosphrenyl treatment, an antibiotic therapy, and homeopathic, herbal treatments. Phosphrenyl treatment is similar to interferon treatment for Hepatitis C, utilized as both a therapeutic and prophylactic agent. Antibiotic therapies are useful as many disease vectors responsible for transmission of tick-borne encephalitis also carry many other tick-borne diseases. An antibiotic therapy may be helpful in anticipating any potential tick-borne co-infections. Antibiotics have also been useful in deactivating certain characteristics of the virus. However certain antibiotic therapies have proven to activate the virus. Thus for this reason, certain antibiotics, such as [[streptomycin]], should not be prescribed during the course of infection. Homeopathic therapies, such as ledum, motherwort, and blackcurrant have inactivating effects on tick-borne encephalitis virus.
| | No specific treatment has been outlined for Tick-borne encephalitis. Progression of the illness may lead to stages and complications that require hospitalization and supportive treatment.<ref name="treat">Treatment. Centers for Disease Control and Prevention. http://www.cdc.gov/vhf/tbe/treatment/index.html Accessed March 10, 2016.</ref> |
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| ==Medical Therapy== | | ==Medical Therapy== |
| *The mainstay medical therapy for tick-borne encephalitis is [Phosphrenyl]] treatment. | | *No specific treatments or therapies have been developed for Tick-borne encephalitis virus. |
| *Phosphrenyl treatment including both a therapeutic and prophylactic agent for TBE[[interferon]] treatment. | | *Progression into stages and complication of the disease that result in [[meningeal]] and [[Encephalitis|encephalitic]] manifestations of the virus may require supportive care and hospitalization. |
| *This treatment may be likened to interferon treatment for [[Hepatitis C]].
| | *[[Corticosteroids]], [[Anti-inflammatory drug|anti-inflammatory therapy]], [[intubation]], and [[ventilator]] support may be necessary in supportive therapy.<ref name="treat">Treatment. Centers for Disease Control and Prevention. http://www.cdc.gov/vhf/tbe/treatment/index.html Accessed March 10, 2016.</ref> |
| *Antibiotic treatment may be necessary for potential tick-borne co-infections, such as [[phytotherapy]].<ref>Streptomycin--an activator of persisting tick-borne encephalitis virus.{{cite journal | author = Malenko G, Pogodina V, Karmysheva V | title = [Streptomycin--an activator of persisting tick-borne encephalitis virus] | journal = Vopr Virusol | volume = 29 | issue = 2 | pages = 217-23 | year = 1984 | month=Mar-Apr | id = PMID 6730440}}</ref><ref>Experimental phytotherapy of tick-borne encephalitis.{{cite journal | author = Fokina G, Frolova T, Roĭkhel' V, Pogodina V | title = [Experimental phytotherapy of tick-borne encephalitis] | journal = Vopr Virusol | volume = 36 | issue = 1 | pages = 18-21 | year = 1991 | month=Jan-Feb | id = PMID 1858353}}</ref><ref>Protective effect of a new antiviral preparation of phosprenyl in experimental tick-borne encephalitis.{{cite journal | author = Ozherelkov S, Timofeev A, Novikova G, Deeva A, Narovlianskiĭ A, Sanin A, Pronin A | title = [Protective effect of a new antiviral preparation of phosprenyl in experimental tick-borne encephalitis] | journal = Vopr Virusol | volume = 45 | issue = 1 | pages = 33-7 | year = 2000 | month=Jan-Feb | id = PMID 10695042}} </ref> | |
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| ===Antibiotics===
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| *Although the TBE virus cannot be eradicated from the body, it can be inactivated. It can also be activated.<ref> The search for antibiotics not exerting activating action in the persistence of the tick-borne encephalitis virus. {{cite journal | author = Malenko G, Pogodina V | title = [The search for antibiotics not exerting activating action in the persistence of the tick-borne encephalitis virus] | journal = Vopr Virusol | volume = 34 | issue = 2 | pages = 197-200 | year = . 1989 | month=Mar-Apr | id = PMID 2788330}}</ref>
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| *Certain antibiotics activate the TBE virus while others have no effect.
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| *TBE virus may be a coinfection with a Borrelia Burgdorferi infection, [[Lyme disease]], which needs treatment with antibiotics.
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| *The Russians studied this matter for years and their findings were as follows: gentamicin exerts no activating effect while streptomycin and ten other antibiotics activate the virus. <ref>Effect of gentamycin on persistence of tick-borne encephalitis.{{cite journal | author = Pogodina V, Malenko G, Karmysheva V, Frolova M | title = [Effect of gentamycin on persistence of tick-borne encephalitis] | journal = Vopr Virusol | volume = 44 | issue = 1 | pages = 35-9 | year = 1999 | month=Jan-Feb | id = PMID 10190241}}</ref>
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| ===Homeopathic===
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| *They also found that some herbs inactivated the TBE virus almost completely in mice, as follows: ledum, motherwort and blackcurrant.<ref>Strategy for choosing antibiotics for treating bacterial infections associated with chronic tick-borne encephalitis.{{cite journal | author = Malenko G, Pogodina V, Frolova M, Ivannikova T | title = [Strategy for choosing antibiotics for treating bacterial infections associated with chronic tick-borne encephalitis] | journal = Vopr Virusol | volume = 41 | issue = 3 | pages = 138-41 | year = 1996 | month=May-Jun | id = PMID 8928510}}</ref><ref>The efficacy of lincomycin in tick-borne encephalitis.{{cite journal | author = Votiakov V, Mishaeva N, Protas I, Ierusalimskiĭ A, Shutov A, Kovalenko V, Kichkil'deev N, Samoĭlova T, Drakina S, Zgirovskaia A | title = [The efficacy of lincomycin in tick-borne encephalitis] | journal = Klin Med (Mosk) | volume = 70 | issue = 1 | pages = 65-7 | year = 1992 | id = PMID 1608216}}</ref>
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| ==References== | | ==References== |
| {{Reflist|2}} | | {{Reflist|2}} |
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| | [[Category: Infectious Disease]] |