Transient hypogammaglobulinemia of infancy

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Transient hypogammaglobulinemia of infancy
ICD-10 D80.7
ICD-9 279.09
eMedicine ped/2280 

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also sometimes IgA[1] and IgM.[2] (The ratios of immunoglobulins vary rapidly in all infants, and the term dysgammaglobulinemia, although theoretically applicable, isn't usually used in this context.)

It can result in increased infections, but it can also present without symptoms.[3]

Historical Perspective

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Pathophysiology

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Treatment

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References

  1. "Transient Hypogammaglobulinemia of Infancy: Immunodeficiency Disorders: Merck Manual Professional". Retrieved 2008-03-01. 
  2. Kiliç SS, Tezcan I, Sanal O, Metin A, Ersoy F (2000). "Transient hypogammaglobulinemia of infancy: clinical and immunologic features of 40 new cases". Pediatr Int. 42 (6): 647–50. PMID 11192522. 
  3. Hsueh KC, Chiu HH, Lin HC, Hsu CH, Tsai FJ (2005). "Transient hypogammaglobulinemia of infancy presenting as Staphylococcus aureus sepsis with deep neck infection". J Microbiol Immunol Infect. 38 (2): 141–4. PMID 15843860. 



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