Thiomorpholine-carboxylate dehydrogenase

Jump to: navigation, search

In enzymology, a thiomorpholine-carboxylate dehydrogenase (EC 1.5.1.25) is an enzyme that catalyzes the chemical reaction

thiomorpholine 3-carboxylate + NAD(P)+ 3,4-dehydro-thiomorpholine-3-carboxylate + NAD(P)H + H+

The 3 substrates of this enzyme are thiomorpholine 3-carboxylate, NAD+, and NADP+, whereas its 4 products are 3,4-dehydro-thiomorpholine-3-carboxylate, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is thiomorpholine-3-carboxylate:NAD(P)+ 5,6-oxidoreductase. Other names in common use include ketimine reductase, and ketimine-reducing enzyme.

References

  • IUBMB entry for 1.5.1.25
  • BRENDA references for 1.5.1.25 (Recommended.)
  • PubMed references for 1.5.1.25
  • PubMed Central references for 1.5.1.25
  • Google Scholar references for 1.5.1.25
  • Nardini M, Ricci G, Caccuri AM, Solinas SP, Vesci L, Cavallini D (1988). "Purification and characterization of a ketimine-reducing enzyme". Eur. J. Biochem. 173: 689&ndash, 94. PMID 3371353.

External links

The CAS registry number for this enzyme class is 115232-54-7.

Gene Ontology (GO) codes

Template:1.5-enzyme-stub


Linked-in.jpg