Sarcomatoid carcinoma of the lung epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
Sarcomatoid carcinoma of the lung is a rare non-small cell lung cancer with aggressive characteristics. The prevalence of sarcomatoid carcinoma of the lung is approximately 0.4 cases per 100,000 individuals worldwide. The average age of patients being diagnosed is between 65 to 75 years, male to female ratio 4:1. The 3-year and 5-year survival rates for patients with sarcomatoid cancer of lung are 35.8 and 28.7%.
Epidemiology and Demographics
Incidence
Sarcomatoid carcinoma of the lung is a rare type of non-small cell lung cancer with aggressive characteristics. There is no sufficient information on the incidence rate of sarcomatoid carcinoma of the lung. Sarcomatoid carcinoma comprises of 0.3% to 1.3% of total lung malignancies.
Prevalence
- The prevalence of sarcomatoid carcinoma of the lung is approximately 0.4 cases per 100,000 individuals worldwide.[1]
- Sarcomatoid carcinoma comprises of 0.3% to 1.3% of total lung malignancies.[2]
- The overall prevalence of sarcomatoid carcinoma of the lung is 0.1% to 0.4% of all non-small cell lung malignancies.[3]
Case-fatality rate/Mortality rate
- The 3-year and 5-year survival rates for patients with sarcomatoid cancer of lung are 35.8 and 28.7%.[4].
Age
- Sarcomatoid carcinoma of the lung is more commonly diagnosed among patients aged 65 to 75 years old.[5]
- Sarcomatoid carcinoma of the lung is more commonly observed among elderly patients and adults.
- Biphasic blastoma subtype is an exception with average age of 35 years old patients being more commonly diagnosed.
Race
- There is no racial predilection to sarcomatoid carcinoma of the lung.
Gender
- Males are more commonly affected with sarcomatoid carcinoma of the lung than females. The male to female ratio is 4:1.[6][4][5]
- Biphasic blastoma subtype is an exception, that affects men and women equally.
Region
- Geographical location has no effect on the epidemiology of sarcomatoid carcinoma of the lung.
References
- ↑ Franks TJ, Galvin JR (2010). "Sarcomatoid carcinoma of the lung: histologic criteria and common lesions in the differential diagnosis". Arch. Pathol. Lab. Med. 134 (1): 49–54. doi:10.1043/2008-0547-RAR.1. PMID 20073605.
- ↑ Travis WD; Brambilla E; Müller-Hermelink K; Harris C; Kleihues C; Sobin P. https://www.iarc.fr/wp-content/uploads/2018/07/BB10.pdf
|chapterurl=missing title (help) (PDF). World Health Organization Classification of Tumours; Pathology and genetics of tumors of the lung, pleura, thymus, and heart. IARC Press. pp. 53–58. ISBN ISBN 92 832 2418 3 Check|isbn=value: invalid character (help). - ↑ Brambilla, E.; Travis, W.D.; Colby, T.V.; Corrin, B.; Shimosato, Y. (2001). "The new World Health Organization classification of lung tumours". European Respiratory Journal. 18 (6): 1059–1068. doi:10.1183/09031936.01.00275301. ISSN 0903-1936.
- ↑ 4.0 4.1 Roesel, Christian; Terjung, Sarah; Weinreich, Gerhard; Hager, Thomas; Chalvatzoulis, Eleftherios; Metzenmacher, Martin; Welter, Stefan (2016). "Sarcomatoid carcinoma of the lung: a rare histological subtype of non-small cell lung cancer with a poor prognosis even at earlier tumour stages". Interactive CardioVascular and Thoracic Surgery: ivw392. doi:10.1093/icvts/ivw392. ISSN 1569-9293.
- ↑ 5.0 5.1 Ouziane, Imane; Boutayeb, Saber; Mrabti, Hind; Lalya, Issam; Rimani, Mouna; Errihani, Hassan (2014). "Sarcomatoid carcinoma of the lung: A model of resistance of chemotherapy". North American Journal of Medical Sciences. 6 (7): 342. doi:10.4103/1947-2714.136920. ISSN 1947-2714.
- ↑ Petrov, D.B; Vlassov, V.I; Kalaydjiev, G.T; Plochev, M.A; Obretenov, E.D; Stanoev, V.I; Danon, S.E (2003). "Primary pulmonary sarcomas and carcinosarcomas – postoperative results and comparative survival analysis". European Journal of Cardio-Thoracic Surgery. 23 (4): 461–466. doi:10.1016/S1010-7940(03)00024-1. ISSN 1010-7940.