Sandbox dfd
1. BEFORE YOU START
1.1 Resources
1.1.1 DailyMed
- 1.1.1.1 DailyMed is a public service provided by the National Library of Medicine (NLM) that encompasses FDA approved labels (package inserts) of marketed drugs.
1.1.2 Drugs@FDA
- 1.1.2.1 Drugs@FDA is a searchable catalog of FDA approved drug products (both prescription and over the counter) which is also useful for confirmation of the marketing status.
1.1.3 Pillbox
- 1.1.3.1 Pillbox is developed to aid in the identification of unknown pills (oral solid dosage form medications). It combines images of pills with appearance and other information to enable users to visually search for and identify oral solid dosage form medications.
- 1.1.3.2 Once a pill has been identified, additional information is provided, including brand/generic name, ingredients, and the National Drug File identification number.
- 1.1.3.3 Links are provided to NLM drug information resources, such as drug labels from DailyMed and the Drug Information Portal, which searches NIH and FDA drug information resources.
1.1.4 Drug Information Portal
- 1.1.4.1 Drug Information Portal provides links to information on breastfeeding (LactMed), drug-induced liver injury (LiverTox), manufacturers drug label (DailyMed), clinical trials (ClinicalTrials.gov), and drug Identification and Image Display (Pillbox beta).
- 1.1.4.2 For detailed information, it also provides links to reviewed biological and physical data (HSDB), references from scientific journals (Medline/PubMed), references from toxicological journals (TOXLINE), biological activities and chemical structures (PubChem), biological activities against HIV/AIDS and other viruses (NIAID ChemDB), toxicological and chemical resources (ChemIDplus), information from the US Food & Drug Administration (Drugs@FDA), and information from the US Drug Enforcement Administration (DEA)
1.1.5 MedlinePlus
- 1.1.5.1 MedlinePlus is a service of the National Library of Medicine (NLM) which contains information for drugs, herbs, and supplements.
1.2 Generic name, active ingredient, formulation, combination, trade name, label
1.2.1 What is the generic name?
- 1.2.1.1 Search and confirm the generic name of the drug.
- 1.2.1.2 Use the generic name as the title of the landing page.
1.2.2 What is the active ingredient? Is there more than one formulation for the active ingredient?
- 1.2.2.1 Search and confirm the formulation(s) of the active ingredient.
- 1.2.2.2 If there is more than one formulation, place links (as <h3> headings) of each formulation on the top of the landing page.
1.2.3 Is the active ingredient provided as combinations with other active ingredients?
- 1.2.3.1 If the active ingredient is also provided as combinations with other active ingredients, place links (as <h3> headings) of each combination on the top of the landing page.
1.2.4 What is the trade name?
- 1.2.4.1 Search and confirm the trade names for the generic name. Please note that the trade name may be identical to the generic name in certain cases.
- 1.2.4.2 Search and confirm the trade names for each formulation and combination (if any). Different formulations may have identical trade names.
- 1.2.4.3 Include the trade names of each formulation and/or combination in parentheses.
- 1.2.4.4 Sort the list of formulations and/or combinations in alphabetical order.
1.2.5 Which label should be used?
- 1.2.5.1 Check the Marketing Start Date and the Revised date at the end of the label.
- 1.2.5.2 For a specific formulation of an active ingredient, use the label that is most recently updated as a reference.
1.2.6 Example
- For the generic name metoprolol, there are two formulations of the active ingredient: metoprolol succinate and metoprolol tartrate.
- The formulations, combinations, and trade names are as follows:
2. Creating or editing a drug page
2.1 Landing page
2.1.1 Go to WikiDoc.
2.1.2 Search with the generic name.
2.1.3 The generic name page should be organized as a landing page if multiple formulations or combinations exist.
2.1.4 At the top of the landing page, place the links (as <h3> headings) of formulations and/or combinations followed by trade names in parentheses (See Section 1.2 for instructions).
- 2.1.4.1 <h3> headings should begin and end with three "=" signs.
- 2.1.4.2 Example: ===[[Metoprolol succinate]] ([[Toprol XL]], [[Toprolxl XL]])===
2.1.5 Redirect the trade name pages to the generic name with formulation pages.
- 2.1.5.1 Example 1: Redirect Lopressor to Metoprolol tartrate.
- 2.1.5.2 Example 2: Redirect both Toprol XL and Toprolxl XL to Metoprolol succinate.
2.1.6 Create or edit the Overview section and Category section.
- 2.1.6.1 The Overview section should include information about the drug class, usage, and adverse reactions.
- 2.1.6.2 The Category section should include all applicable categories for the drug in alphabetical order.
- 2.1.6.3 The name of category should be identical to the official FDA category.
2.2 Using the Drug Project Form
2.2.1 To create a drug page, Go to Form:DrugProjectForm.
2.2.2 Use the appropriate title for the drug page.
- 2.2.2.1 If there is more than one formulation for a generic name, use the generic name with formuation as the title.
- 2.2.2.1.1 Example 1: Metoprolol succinate as the title.
- 2.2.2.1.2 Example 2: Metoprolol tartrate as the title.
- 2.2.2.2 If there are combinations with other active ingredients, use the combination of each ingredient separated by the "/" sign as the title.
- 2.2.2.2.1 Example 1: Metoprolol succinate/Hydrochlorothiazide as the title.
- 2.2.2.2.2 Example 2: Metoprolol tartrate/Arginine as the title.
2.2.3 Enter the title for the drug page in the field and left-click on the "Create or edit a Drug Page" button.
2.2.4 Follow the instructions under each tab to insert contents.
2.2.5 Left-click on the "Save" button after completing each tab to minimize the risk of losing progress.
2.2.6 Quality check the completed section before proceeding to the next section.