Rizatriptan contraindications

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Rizatriptan
MAXALT® FDA Package Insert
Indications and Usage
Dosage and Administration
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
Nonclinical Toxicology
Clinical Studies
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Rizatriptan
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Contraindications

MAXALT is contraindicated in patients with:

  • Ischemic coronary artery disease (angina pectoris, history of myocardial infarction, or documented silent ischemia), or other significant underlying cardiovascular disease [see Warnings and Precautions (5.1)].
  • Coronary artery vasospasm including Prinzmetal's angina [see Warnings and Precautions (5.1)].
  • History of stroke or transient ischemic attack (TIA) [see Warnings and Precautions (5.4)].
  • Peripheral vascular disease (PVD) [see Warnings and Precautions (5.5)].
  • Ischemic bowel disease [see Warnings and Precautions (5.5)].
  • Uncontrolled hypertension [see Warnings and Precautions (5.8)].
  • Recent use (i.e., within 24 hours) of another 5-HT1 agonist, ergotamine-containing medication, or ergot-type medication (such as dihydroergotamine or methysergide) [see Drug Interactions (7.2 and 7.3)].
  • Hemiplegic or basilar migraine [see Indications and Usage (1)].
  • Concurrent administration or recent discontinuation (i.e., within 2 weeks) of a MAO-A inhibitor [see Drug Interactions (7.5) and Clinical Pharmacology (12.3)].
  • Hypersensitivity to MAXALT or MAXALT-MLT (angioedema and anaphylaxis seen) [see Adverse Reactions (6.2)].[1]

References

  1. "MAXALT (RIZATRIPTAN BENZOATE) TABLET MAXALT-MLT (RIZATRIPTAN BENZOATE) TABLET, ORALLY DISINTEGRATING [MERCK SHARP & DOHME CORP.]".

Adapted from the FDA Package Insert.