Post-streptococcal glomerulonephritis
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| Post-streptococcal glomerulonephritis Classification and external resources | |
| ICD-9 | 580.0 |
|---|---|
| DiseasesDB | 29306 |
| MedlinePlus | 000503 |
| eMedicine | med/889 |
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In nephrology, post-streptococcal glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys, following an streptococci infection. This condition is essentially defined as an inflammation of the kidneys.
A closely related term is "post-infectious glomerulonephritis", which accounts for infections by other agents. However, this term is used much less frequently.
Pathophysiology
The exact pathology remains unclear, but it is believed to be Type III hypersensitivity reaction. Immune complexes (antigen-antibody complexes formed during an infection) become lodged in the glomerular basement membrane. Complement activation leads to destruction of the basement membrane. It has also been proposed that specific antigens from certain nephrotoxic streptococcal infections have a high affinity for basement membrane proteins, giving rise to particularly severe, long lasting antibody response.
Presentation
Patients will present with acute nephritic syndrome, with the pentad of hypertension, decrease in glomerular filtration rate, hematuria, proteinuria and fluid retention.
Causes
Post-infectious glomerulonephritis can be a complication of streptococcal pharyngitis (strep throat).
Diagnosis
Diagnosis rarely requires a renal biopsy since there is usually a classical clinical presentation. There will be elevated levels of ASOT Ab and low complement levels in the blood.
External links
WikiDoc Research Resources for Post-streptococcal glomerulonephritis | |
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| Articles on Post-streptococcal glomerulonephritis | Most recent articles on Post-streptococcal glomerulonephritis • Most cited articles on Post-streptococcal glomerulonephritis • Review articles on Post-streptococcal glomerulonephritis • Articles on Post-streptococcal glomerulonephritis in N Eng J Med, Lancet, BMJ |
| Media (Slides, Video, Images, MP3) on Post-streptococcal glomerulonephritis | Powerpoint slides on Post-streptococcal glomerulonephritis • Images of Post-streptococcal glomerulonephritis • Photos of Post-streptococcal glomerulonephritis • Podcasts & MP3s on Post-streptococcal glomerulonephritis • Videos on Post-streptococcal glomerulonephritis |
| Evidence Based Medicine Regarding Post-streptococcal glomerulonephritis | Cochrane Collaboration on Post-streptococcal glomerulonephritis • Bandolier on Post-streptococcal glomerulonephritis • TRIP on Post-streptococcal glomerulonephritis |
| Cost Effectiveness of Post-streptococcal glomerulonephritis | Cost Effectiveness of Post-streptococcal glomerulonephritis |
| Clinical Trials Involving Post-streptococcal glomerulonephritis | Ongoing Trials on Post-streptococcal glomerulonephritis at Clinical Trials.gov • Trial results on Post-streptococcal glomerulonephritis • Clinical Trials on Post-streptococcal glomerulonephritis at Google |
| Guidelines / Policies / Government Resources (FDA/CDC) Regarding Post-streptococcal glomerulonephritis | US National Guidelines Clearinghouse on Post-streptococcal glomerulonephritis • NICE Guidance on Post-streptococcal glomerulonephritis • NHS PRODIGY Guidance • FDA on Post-streptococcal glomerulonephritis • CDC on Post-streptococcal glomerulonephritis |
| Textbook Information on Post-streptococcal glomerulonephritis | Books and Textbook Information on Post-streptococcal glomerulonephritis |
| Pharmacology Resources on Post-streptococcal glomerulonephritis | Dosing of Post-streptococcal glomerulonephritis • Drug interactions with Post-streptococcal glomerulonephritis • Side effects of Post-streptococcal glomerulonephritis • Allergic reactions to Post-streptococcal glomerulonephritis • Overdose information on Post-streptococcal glomerulonephritis • Carcinogenicity information on Post-streptococcal glomerulonephritis • Post-streptococcal glomerulonephritis in pregnancy • Pharmacokinetics of Post-streptococcal glomerulonephritis • |
| Genetics, Pharmacogenomics, and Proteinomics of Post-streptococcal glomerulonephritis | Genetics of Post-streptococcal glomerulonephritis • Pharmacogenomics of Post-streptococcal glomerulonephritis • Proteomics of Post-streptococcal glomerulonephritis |
| Newstories on Post-streptococcal glomerulonephritis | Post-streptococcal glomerulonephritis in the news • Be alerted to news on Post-streptococcal glomerulonephritis • News trends on Post-streptococcal glomerulonephritis |
| Commentary on Post-streptococcal glomerulonephritis | Blogs on Post-streptococcal glomerulonephritis |
| Patient Resources on Post-streptococcal glomerulonephritis | Patient resources on Post-streptococcal glomerulonephritis • Discussion groups on Post-streptococcal glomerulonephritis • Patient Handouts on Post-streptococcal glomerulonephritis • Directions to Hospitals Treating Post-streptococcal glomerulonephritis • Risk calculators and risk factors for Post-streptococcal glomerulonephritis |
| Healthcare Provider Resources on Post-streptococcal glomerulonephritis | Symptoms of Post-streptococcal glomerulonephritis • Causes & Risk Factors for Post-streptococcal glomerulonephritis • Diagnostic studies for Post-streptococcal glomerulonephritis • Treatment of Post-streptococcal glomerulonephritis |
| Continuing Medical Education (CME) Programs on Post-streptococcal glomerulonephritis | CME Programs on Post-streptococcal glomerulonephritis |
| International Resources on Post-streptococcal glomerulonephritis | Post-streptococcal glomerulonephritis en Espanol • Post-streptococcal glomerulonephritis en Francais |
| Business Resources on Post-streptococcal glomerulonephritis | Post-streptococcal glomerulonephritis in the Marketplace • Patents on Post-streptococcal glomerulonephritis |
| Informatics Resources on Post-streptococcal glomerulonephritis | List of terms related to Post-streptococcal glomerulonephritis |
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
