Polychondritis

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Polychondritis
DiseasesDB 10248
eMedicine med/2000  derm/375

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Polychondritis is an auto-immune disease in which the human body's immune system begins to attack and destroy the cartilage tissues in the body.

All cartilage areas can be affected, though in many cases the disease will affect several areas where cartilage is found in the body, and leave others entirely alone. Parts of the body with cartilage, and therefore potentially affected by polychondritis, include the ears, nose, throat, heart valves and of course all areas where musculo-skeletal tissues are connected by cartilage. Specific resultant conditions may include Type 3 Tracheomalacia and Vasculitis.

Reasons for disease onset are not known. Treatment plans typically involve suppression of the immune system with medicines, which often result in a side effect of increasing the risk of other infections.

While the disease can come on at various times, most frequent time for onset is in the late 40's to early 50's. Some literature reports a slightly higher occurrence in females than males, while other literature asserts that sex is apparently not a statistically significant factor in the occurrence rate of the disease. Polychondritis is one of many subclasses of disease in the area of Rheumatology.

Polychondritis is classified in Chapter 13 of the International Statistical Classification of Diseases and Related Health Problems: ICD-10 Chapter XIII: Diseases of the musculoskeletal system and connective tissue. It is also known as Relapsing polychondritis, Chronic atrophic polychondritis, Meyenburg-Altherr-Uehlinger syndrome, von Meyenburg's disease, Generalized chondromalacia, or Systemic chondromalacia.

Diagnosis

Physical Examination

skin

Ear

References

  1. 1.0 1.1 1.2 1.3 1.4 "Dermatology Atlas".


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| group5 = Clinical Trials Involving Polychondritis | list5 = Ongoing Trials on Polychondritis at Clinical Trials.govTrial results on PolychondritisClinical Trials on Polychondritis at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Polychondritis | list6 = US National Guidelines Clearinghouse on PolychondritisNICE Guidance on PolychondritisNHS PRODIGY GuidanceFDA on PolychondritisCDC on Polychondritis


| group7 = Textbook Information on Polychondritis | list7 = Books and Textbook Information on Polychondritis


| group8 = Pharmacology Resources on Polychondritis | list8 = AND (Dose)}} Dosing of PolychondritisAND (drug interactions)}} Drug interactions with PolychondritisAND (side effects)}} Side effects of PolychondritisAND (Allergy)}} Allergic reactions to PolychondritisAND (overdose)}} Overdose information on PolychondritisAND (carcinogenicity)}} Carcinogenicity information on PolychondritisAND (pregnancy)}} Polychondritis in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Polychondritis


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Polychondritis | list9 = AND (pharmacogenomics)}} Genetics of PolychondritisAND (pharmacogenomics)}} Pharmacogenomics of PolychondritisAND (proteomics)}} Proteomics of Polychondritis


| group10 = Newstories on Polychondritis | list10 = Polychondritis in the newsBe alerted to news on PolychondritisNews trends on Polychondritis


| group11 = Commentary on Polychondritis | list11 = Blogs on Polychondritis

| group12 = Patient Resources on Polychondritis | list12 = Patient resources on PolychondritisDiscussion groups on PolychondritisPatient Handouts on PolychondritisDirections to Hospitals Treating PolychondritisRisk calculators and risk factors for Polychondritis


| group13 = Healthcare Provider Resources on Polychondritis | list13 = Symptoms of PolychondritisCauses & Risk Factors for PolychondritisDiagnostic studies for PolychondritisTreatment of Polychondritis

| group14 = Continuing Medical Education (CME) Programs on Polychondritis | list14 = CME Programs on Polychondritis

| group15 = International Resources on Polychondritis | list15 = Polychondritis en EspanolPolychondritis en Francais

| group16 = Business Resources on Polychondritis | list16 = Polychondritis in the MarketplacePatents on Polychondritis

| group17 = Informatics Resources on Polychondritis | list17 = List of terms related to Polychondritis


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