Pimeloyl-CoA dehydrogenase

Jump to: navigation, search

In enzymology, a pimeloyl-CoA dehydrogenase (EC 1.3.1.62) is an enzyme that catalyzes the chemical reaction

pimeloyl-CoA + NAD+ 6-carboxyhex-2-enoyl-CoA + NADH + H+

Thus, the two substrates of this enzyme are pimeloyl-CoA and NAD+, whereas its 3 products are 6-carboxyhex-2-enoyl-CoA, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is pimeloyl-CoA:NAD+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

References

  • IUBMB entry for 1.3.1.62
  • BRENDA references for 1.3.1.62 (Recommended.)
  • PubMed references for 1.3.1.62
  • PubMed Central references for 1.3.1.62
  • Google Scholar references for 1.3.1.62
  • Gallus C, Schink B (1994). "Anaerobic degradation of pimelate by newly isolated denitrifying bacteria". Microbiology. 140: 409&ndash, 16. PMID 8180704.

External links

Gene Ontology (GO) codes

Template:1.3-enzyme-stub


Linked-in.jpg