Phosphate nephropathy pathology

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The characteristic finding on the renal biopsy is the extensive deposition of calcium phosphate, mostly in the tubular lumen and less commonly in the peritubular interstitium. The calcium phosphates can be identified using von Kossa stain, also they lack birefringence under polarized light. Other findings can be divided on the basis of the time at which the biopsy is performed:

Early finding

Late finding