POU family

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POU (pronounced 'pow') is a family of proteins that have well-conserved homeodomains.

Function

POU proteins are eukaryotic transcription factors containing a bipartite DNA binding domain referred to as the POU domain.

The various members of the POU family have a wide variety of functions, all of which are related to the development of an organism.

Etymology

The acronym POU is derived from the names of three mammalian transcription factors:

Diversity

POU domain genes have been described in organisms as divergent as Caenorhabditis elegans, Drosophila, Xenopus, zebrafish and human but have not been yet identified in plants and fungi.

Genes

External links



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