Na-K-2Cl symporter

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solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Identifiers
SymbolSLC12A1
Entrez6557
HUGO10910
OMIM600839
RefSeqNM_000338
UniProtQ13621
Other data
LocusChr. 15 q15-q21
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
Identifiers
SymbolSLC12A2
Entrez6558
HUGO10911
OMIM600840
RefSeqNM_001046
UniProtP55011
Other data
LocusChr. 5 q23.3

The Na-K-2Cl symporter is a carrier protein that is inhibited by loop diuretics. There are two main genes depending on where the protein is expressed. NKCC2 is expressed in the ascending loop of Henle and NKCC1 is expressed in all other cells that use this function.

See also

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