In enzymology, a N-sulfoglucosamine-3-sulfatase (EC 220.127.116.11) is an enzyme that catalyzes the chemical reaction of cleaving off the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.
This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is N-sulfo-3-sulfoglucosamine 3-sulfohydrolase. This enzyme is also called chondroitinsulfatase. This enzyme participates in the degradtaion of glycan structures.
- IUBMB entry for 18.104.22.168
- BRENDA references for 22.214.171.124 (Recommended.)
- PubMed references for 126.96.36.199
- PubMed Central references for 188.8.131.52
- Google Scholar references for 184.108.40.206
- Bruce JS, McLean MW, Long WF, Williamson FB (1985). "Flavobacterium heparinum 3-O-sulphatase for N-substituted glucosamine 3-O-sulphate". Eur. J. Biochem. 148: 359&ndash, 65. PMID 3987694.
- Leder IG (1980). "A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamino-alphs-D-glucopyranoside 3-sulfate". Biochem. Biophys. Res. Commun. 94: 1183&ndash, 9. PMID 7396957.
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