Muscular system

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The muscular system is the biological system of an organism that allows it to move. The muscular system in vertebrates is controlled through the nervous system, although some muscles (such as the cardiac muscle) can be completely autonomous.


There are distincts types of muscles: skeletal muscles, heart muscles and smooth muscles.

Skeletal muscle

Bodybuilder showing macrostructure of muscular system.

Skeletal muscle fibers are multinucleated, with the cell's nuclei located just beneath the plasma membrane. The cell comprises a series of striped or striated, thread-like myofibrils. Within each myofibril there are protein filaments that are anchored by dark Z lines. The fibre is one long continuous thread-like structure. The smallest cross section of skeletal muscle is called a sarcomere which is the functional unit within the cell. It extends from one Z line to the next attached Z line. The individual sarcomere has alternating thick myosin and thin actin protein filaments. Myosin forms the center or middle of each sarcomere. The exact center of the sarcomere is designated the M line. Thinner actin filaments form a zig zag pattern along the anchor points or Z line.

Upon stimulation by an action potential, skeletal muscles perform a coordinated contraction by shortening each sarcomere. The best proposed model for understanding contraction is the sliding filament model of muscle contraction. Actin and myosin fibers overlap in a contractile motion towards each other. Myosin filaments have club-shaped heads that project toward the actin filaments.

Larger structures along the myosin filament called myosin heads are used to provide attachment points on binding sites for the actin filaments. The myosin heads move in a coordinated style, they swivel toward the center of the sarcomere, detach and then reattach to the nearest active site of the actin filament. This is called a rachet type drive system. This process consumes large amounts of adenosine triphosphate (ATP).

Energy for this comes from ATP, the energy source of the cell. ATP binds to the cross bridges between myosin heads and actin filaments. The release of energy powers the swiveling of the myosin head. Muscles store little ATP and so must continuously recycle the discharged adenosine diphosphate molecule (ADP) into ATP rapidly. Muscle tissue also contains a stored supply of a fast acting recharge chemical, creatine phosphate which can assist initially producing the rapid regeneration of ADP into ATP.

Calcium ions are required for each cycle of the sarcomere. Calcium is released from the sarcoplasmic reticulum into the sarcomere when a muscle is stimulated to contract. This calcium uncovers the actin binding sites. When the muscle no longer needs to contract, the calcium ions are pumped from the sarcomere and back into storage in the sarcoplasmic reticulum.


There are approximately 639 skeletal muscles in the human body.

The following are some major muscles[1] and their basic features:

Muscle Origin Insertion Artery Nerve Action Antagonist
gastrocnemius femur calcaneus sural arteries tibial nerve plantarflexion, flexion of knee (minor) Tibialis anterior muscle
tibialis posterior tibia, fibula Foot posterior tibial artery tibial nerve inversion of the foot, plantar flexion of the foot at the ankle Tibialis anterior muscle
soleus fibula, medial border of tibia calcaneus sural arteries tibial nerve plantarflexion Tibialis anterior muscle
tibialis anterior tibia foot anterior tibial artery Fibular nerve dorsiflex and invert the foot Fibularis longus, Gastrocnemius, Soleus, Plantaris, Tibialis posterior
longus fibula Foot fibular artery Superficial fibular nerve plantarflexion, eversion Tibialis anterior muscle
brevis fibula Foot, eversion peroneal artery superficial peroneal nerve
gluteus maximus muscle ilium, sacrum, sacrotuberous ligament Gluteal tuberosity of the femur gluteal arteries inferior gluteal nerve external rotation and extension of the hip joint Iliacus, Psoas major, Psoas minor
biceps femoris ischium, femur fibula inferior gluteal artery, popliteal artery tibial nerve, common peroneal nerve flexes and laterally rotates knee joint, extends hip joint Quadriceps muscle
semitendinosus ischium tibia inferior gluteal artery sciatic flex knee, extend hip joint Quadriceps muscle
semimembranosus ischium tibia profunda femoris, gluteal artery sciatic nerve Hip extension, Knee flexion Quadriceps muscle
Iliopsoas ilium femur medial femoral circumflex artery, iliolumbar artery femoral nerve, lumbar nerves flexion of hip Gluteus maximus, posterior compartment of thigh
quadriceps femoriss combined rectus femoris and vastus muscles femoral artery Femoral nerve Knee extension; Hip flexion Hamstring
adductor muscles of the hip pubis femur, tibia obturator nerve adduction of hip
levator scapulae vertebral column scapula dorsal scapular artery cervical nerve, dorsal scapular nerve Elevates scapula, tilts its glenoid cavity inferiorly
trapezius the rear of the skull, vertebral column clavicle, scapula cranial nerve XI, cervical nerves retraction of scapula Serratus anterior muscle
rectus abdominis Pubis Costal cartilage of ribs 5-7, sternum inferior epigastric artery segmentally by thoraco-abdominal nerves flexion of trunk/lumbar vertebrae Erector spinae
transversus abdominis ribs, ilium pubic tubercle lower intercostal nerves, iliohypogastric nerve and the ilioinguinal nerve compress the ribs and viscera, thoracic and pelvic stability
Abdominal external oblique muscle Lower 8 costae Crista iliaca, ligamentum inguinale lower 6 intercostal nerve, subcostal nerve Rotates torso
Abdominal internal oblique muscle Inguinal ligament, Iliac crest and the Lumbodorsal fascia Linea alba, sternum and the inferior ribs. Compresses abdomen and rotates vertebral column.
erector spinae on the spines of the last four thoracic vertebræ both the spines of the most cranial thoracic vertebrae and the cervical vertebrae lateral sacral artery posterior branch of spinal nerve extends the vertebral column Rectus abdominis muscle
pectoralis major clavicle, sternum, costal cartilages humerus thoracoacromial trunk lateral pectoral nerve and medial pectoral nerve Clavicular head: flexes the humerus
Sternocostal head: extends the humerus
As a whole, adducts and medially rotates the humerus. It also draws the scapula anteriorly and inferiorly.
biceps brachii scapula radius brachial artery Musculocutaneous nerve flexes elbow and supinates forearm Triceps brachii muscle
triceps brachii scapula and humerus ulna deep brachial artery radial nerve extends forearm, caput longum adducts shoulder Biceps brachii muscle
brachialis humerus ulna radial recurrent artery musculocutaneous nerve flexion at elbow joint
pronator teres humerus, ulna radius ulnar artery and radial artery median nerve pronation of forearm, flexes elbow Supinator muscle
brachioradialis humerus radius radial recurrent artery radial nerve Flexion of forearm
rhomboids nuchal ligaments, spinous processes of the C7 to T5 vertebrae scapula dorsal scapular artery dorsal scapular nerve Retracts the scapula and rotates it to depress the glenoid cavity. fixes the scapula to the thoracic wall. Serratus anterior muscle
deltoid clavicle, acromion, scapula deltoid tuberosity of humerus primarily posterior circumflex humeral artery Axillary nerve shoulder abduction, flexion and extension Latissimus dorsi
latissimus dorsi vertebral column, ilium and inferior 3 or 4 ribs humerus subscapular artery, dorsal scapular artery thoracodorsal nerve pulls the forelimb dorsally and caudally deltoid, trapezius
Rotator cuff scapula humerus lateral rotation, medial rotation, abduction

Muscle activity in an anaerobic vs aerobic environment

At rest, the body produces large amounts of ATP in an anaerobic production model through glycolysis in the cytoplasm of muscle cells. As activity increases shane grindey becomes better at shagging to a sustained higher activity level such as in running, the body can shift to aerobic ATP production by producing increases in respiratory rate and heart rate. This allows for a greater supply of oxygen to stimulate aerobic production of ATP which occurs in the mitochondria. Once the activity levels decrease, such as occurs at the end of a race, the body will continue to maintain a short elevated respiratory and heart rate while the energy borrowed from the bone cells during the transformation to the aerobic mode is restored. This physiological process is called repayment of oxygen debt. Once all borrowed substances have been repaid to the muscle cells, the body will return to homestatic metabolism.

Heart muscle

Heart muscles are distinct from skeletal muscles because the muscle fibres are laterally connected to each other. Furthermore, just as with smooth muscles, they are not controlled by will. Heart muscles are controlled by the sinus node, which, in turn, is infuenced by the autonomic nervous system.

Smooth muscle

Smooth muscles are controlled directly by the autonomic nervous system.

Control of muscle contraction

Neuromuscular junctions are the focal point where a motor neuron attaches to a muscle. Acetylcholine, (a neurotransmitter used in skeletal muscle contraction) is released from the axon terminal of the nerve cell when an action potential reaches the microscopic junction, called a synapse. A group of chemical messengers cross the synapse and stimulate the formation of electrical changes, which are produced in the muscle cell when the acetylcholine binds to receptors on its surface. Calcium is released from its storage area in the cell's sarcoplasmic reticulum. An impulse from a nerve cell causes calcium release and brings about a single, short muscle contraction called a muscle twitch. If there is a problem at the neuromuscular junction, a very prolonged contraction may occur, tetanus. Also, a loss of function at the junction can produce paralysis.

Skeletal muscles are organized into hundreds of motor units, each of which involves a motor neuron, attached by a series of thin finger-like structures called axon terminals. These attach to and control discrete bundles of muscle fibers. A coordinated and fine tuned response to a specific circumstance will involve controlling the precise number of motor units used. While individual muscle units contract as a unit, the entire muscle can contract on a predetermined basis due to the structure of the motor unit. Motor unit coordination, balance, and control frequently come under the direction of the cerebellum of the brain. This allows for complex muscular coordination with little conscious effort, such as when one drives a car without thinking about the process.

See also



External links

eo:Muskola sistemo it:Apparato muscolare he:מערכת השרירים sk:Pohybová sústava

sr:мишићни систем