Methylquercetagetin 6-O-methyltransferase

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In enzymology, a methylquercetagetin 6-O-methyltransferase (EC 2.1.1.84) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone S-adenosyl-L-homocysteine + 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and 5,6,3',4'-tetrahydroxy-3,7-dimethoxyflavone, whereas its two products are S-adenosylhomocysteine and 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase. Other names in common use include flavonol 6-O-methyltransferase, flavonol 6-methyltransferase, 6-OMT, S-adenosyl-L-methionine:3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone, and 6-O-methyltransferase.

References

  • IUBMB entry for 2.1.1.84
  • BRENDA references for 2.1.1.84 (Recommended.)
  • PubMed references for 2.1.1.84
  • PubMed Central references for 2.1.1.84
  • Google Scholar references for 2.1.1.84
  • De Luca V, Ibrahim RK (1985). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases". Arch. Biochem. Biophys. 238: 596&ndash, 605. PMID 3994393.
  • De Luca V, Ibrahim RK (1985). "Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4'-O-methyltransferases". Arch. Biochem. Biophys. 238: 606&ndash, 18. PMID 3994394.

External links

The CAS registry number for this enzyme class is 96477-60-0.

Gene Ontology (GO) codes


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